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Introduction to the Forensic Research via Omics Markers in Environmental Health Vulnerable Areas (FROM) study
Jung-Yeon Kwon, Woo Jin Kim, Yong Min Cho, Byoung-gwon Kim, Seungho Lee, Jee Hyun Rho, Sang‑Yong Eom, Dahee Han, Kyung-Hwa Choi, Jang-Hee Lee, Jeeyoung Kim, Sungho Won, Hee-Gyoo Kang, Sora Mun, Hyun Ju Yoo, Jung-Woong Kim, Kwan Lee, Won-Ju Park, Seongchul Hong, Young-Soub Hong
Epidemiol Health. 2024;e2024062.   Published online July 12, 2024
DOI: https://doi.org/10.4178/epih.e2024062    [Accepted]
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AbstractAbstract PDF
Abstract
OBJECTIVES
Exposure to humidifier disinfectants has been linked to respiratory diseases, including interstitial lung disease, asthma, and pneumonia. Consequently, numerous toxicological studies have explored respiratory damage as both a necessary and sufficient condition for these diseases. We systematically reviewed and integrated evidence from toxicological studies by applying the evidence integration method established in previous research to confirm the biological plausibility of the association between exposure and disease.
METHODS
We conducted a literature search focusing on polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT), the primary ingredients in humidifier disinfectants. We selected relevant studies based on their quality and the population, exposure, comparator, outcome (PECO) statements. These studies were categorized into 3 lines of evidence: hazard information, animal studies, and mechanistic studies. Based on a systematic review, we integrated the evidence to develop an aggregate exposure pathway–adverse outcome pathway (AEP-AOP) model for respiratory damage. The reliability and relevance of our findings were assessed by comparing them with the hypothesized pathogenic mechanisms of respiratory diseases.
RESULTS
The integration of each AEP-AOP component for PHMG and CMIT/MIT led to the development of an AEP-AOP model, wherein disinfectants released from humidifiers in aerosol or gaseous form reached target sites, causing respiratory damage through molecular initiating events and key events. The model demonstrated high reliability and relevance to the pathogenesis of respiratory diseases.
CONCLUSIONS
The AEP-AOP model developed in this study provides strong evidence that exposure to humidifier disinfectants causes respiratory diseases. This model demonstrates the pathways leading to respiratory damage, a hallmark of these conditions.
Summary
Data Profiles
Data resource profile: the Korean Community Health Status Indicators (K-CHSI) database
Hye-Eun Lee, Yeon-gyeong Kim, Jin-Young Jeong, Dong-Hyun Kim
Epidemiol Health. 2023;45:e2023016.   Published online February 2, 2023
DOI: https://doi.org/10.4178/epih.e2023016
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Korean Community Health Status Indicators (K-CHSI) is a model-based database containing annual data on health outcomes and determinants at the municipal level (<i>si/gun/gu</i>-level regions, including mid-sized cities, counties, and districts). K-CHSI’s health outcomes include overall mortality, disease incidence, prevalence rates, and self-reported health. Health determinants were measured in 5 domains: socio-demographic factors, health behaviors, social environment, physical environment, and the healthcare system. The data sources are 71 public databases, including Causes of Death Statistics, Cancer Registration Statistics, Community Health Survey, Population Census, and Census on Establishments and Statistics of Urban Plans. This dataset covers Korea’s 17 metropolitan cities and provinces, with data from approximately 250 municipal regions (<i>si/gun/gu</i>). The current version of the database (DB version 1.3) was built using 12 years of data from 2008 to 2019. All data included in K-CHSI may be downloaded via the Korea Community Health Survey site, with no login requirement (https://chs.kdca.go.kr/chs/recsRoom/dataBaseMain.do). K-CHSI covers extensive health outcomes and health determinants at the municipal level over a period of more than 10 years, which enables ecological and time-series analyses of the relationships among various health outcomes and related factors.
Summary
Korean summary
지역사회 건강관련요인 데이터베이스는 17개 광역시도와 약 250개 시군구의 건강 결과 및 결정 요인에 대한 연간 데이터를 포함하는 모델 기반 데이터베이스이다. 본 데이터베이스의 건강 결과에는 사망률, 질병 발생률, 유병률, 자가 보고 건강상태 등이 포함되며 건강 결정 요인은 인구사회학적 환경, 건강 행태, 사회적 환경, 물리적 환경, 보건의료 체계의 5개 영역으로 구성되었다. 데이터는 질병관리청 지역사회건강조사 사이트에서 로그인 없이 다운로드할 수 있다(https://chs.kdca.go.kr/chs/recsRoom/dataBaseMain.do).
Key Message
Korean Community Health Status Indicators (K-CHSI) is a model-based database containing annual data on health outcomes and determinants from 17 metropolitan cities and provinces, with data from approximately 250 municipal regions (si/gun/gu). K-CHSI’s health outcomes include overall mortality, disease incidence, prevalence rates, and self-reported health. Health determinants were measured in 5 domains: socio-demographic factors, health behaviors, social environment, physical environment, and the healthcare system. The data included in K-CHSI may be downloaded via the Korea Community Health Survey site, with no login requirement (https://chs.kdca.go.kr/chs/recsRoom/dataBaseMain.do).
The National Hospice and Palliative Care registry in Korea
Kyuwoong Kim, Bohyun Park, Bonju Gu, Eun Jeong Nam, Sue Hyun Kye, Jin Young Choi
Epidemiol Health. 2022;44:e2022079.   Published online September 21, 2022
DOI: https://doi.org/10.4178/epih.e2022079
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  • 5 Web of Science
  • 7 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
The National Hospice and Palliative Care (NHPC) registry is a nationwide database in Korea that systematically collects information on terminally ill cancer patients receiving inpatient hospice care. From 2018 to 2020, a total of 47,911 patients were enrolled in the NHPC registry from hospitals providing inpatient hospice care. The NHPC database mainly contains the socio-demographic and clinical information of the registered patients. Among these patients, approximately 75% were 60 years or older, and the ratio of males to females was 1:1.41. Lung, liver, colorectal, pancreatic, and gastric cancer made up nearly 90% of the cancer sites among the registered patients. Upon their initial admission to the hospice ward, around 80% of the patients were aware of their terminal illness. About half of the patients had mild pain at the time of the initial admission to the hospice ward, and the duration of hospice care was 14 days (interquartile range, 6-30) in 2019 and 2020. The NHPC registry aims to provide national statistics on inpatient hospice care to assist health policy-making.
Summary
Korean summary
본 논문에서 소개된 국가 호스피스·완화의료 등록시스템은 국내 입원형 호스피스 환자의 인구사회학적 특성과 임상정보에 관한 정보를 포함하고 있습니다. 등록시스템은 국내 호스피스·완화의료 현황에 대한 국가통계 생산, 근거기반 호스피스·완화의료 정책 개발 및 연구 등에 활용될 수 있습니다.
Key Message
The National Hospice and Palliative Care registry contains information on demographics and clinical information of patients receiving inpatient hospice care in Korea. Along with its primary purpose to provide national statistics on the current status of hospice care in the country, the registry could also be used for evidence-based health policy or research pertaining to hospice in Korea.

Citations

Citations to this article as recorded by  
  • For the Universal Right to Access Quality End-of-Life Care in Korea: Broadening Our Perspective After the 2018 Life-Sustaining Treatment Decisions Act
    Hye Yoon Park, Min Sun Kim, Shin Hye Yoo, Jung Lee, In Gyu Song, So Yeon Jeon, Eun Kyung Choi
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Differences in end-of-life care patterns between types of hospice used for cancer patients: a retrospective cohort study
    Il Yun, Eun-Cheol Park, Chung Mo Nam, Jaeyong Shin, Suk-Yong Jang, Sung-In Jang
    BMC Palliative Care.2024;[Epub]     CrossRef
  • Inpatient Hospice Care in Korea during the COVID-19 Pandemic: A Preliminary Study
    Youn Seon Choi, Sun Wook Hwang, In Cheol Hwang
    Journal of Hospice and Palliative Care.2024; 27(2): 82.     CrossRef
  • Decreased aggressive care at the end of life among advanced cancer patients in the Republic of Korea: a nationwide study from 2012 to 2018
    Sara Kwon, Kyuwoong Kim, Bohyun Park, So-Jung Park, Hyun Jung Jho, Jin Young Choi
    BMC Palliative Care.2024;[Epub]     CrossRef
  • Advance Care Planning in South Korea
    Yu Jung Kim, Sun-Hyun Kim
    Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen.2023; 180: 68.     CrossRef
  • Changes in the Place of Death of Patients With Cancer After the Introduction of Insurance-Covered, Home-Based Hospice Care in Korea
    Il Yun, Sung-In Jang, Eun-Cheol Park, Suk-Yong Jang
    JAMA Network Open.2023; 6(11): e2341422.     CrossRef
  • Application of Acceptance and Commitment Therapy (ACT) in Hospice and Palliative Care Settings
    So-Young Park
    The Journal of Hospice and Palliative Care.2023; 26(3): 140.     CrossRef
Integrated dataset of the Korean Genome and Epidemiology Study cohort with estimated air pollution data
Hae Dong Woo, Dae Sub Song, Sun Ho Choi, Jae Kyung Park, Kyoungho Lee, Hui-Young Yun, Dae-Ryun Choi, Youn-Seo Koo, Hyun-Young Park
Epidemiol Health. 2022;44:e2022071.   Published online September 7, 2022
DOI: https://doi.org/10.4178/epih.e2022071
  • 7,262 View
  • 245 Download
  • 4 Web of Science
  • 4 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Public concern about the adverse health effects of air pollution has grown rapidly in Korea, and there has been increasing demand for research on ways to minimize the health effects of air pollution. Integrating large epidemiological data and air pollution exposure levels can provide a data infrastructure for studying ambient air pollution and its health effects. The Korean Genome and Epidemiology Study (KoGES), a large population-based study, has been used in many epidemiological studies of chronic diseases. Therefore, KoGES cohort data were linked to air pollution data as a national resource for air pollution studies. Air pollution data were produced using community multiscale air quality modeling with additional adjustment of monitoring data, satellite-derived aerosol optical depth, normalized difference vegetation index, and meteorological data to increase the accuracy and spatial resolution. The modeled air pollution data were linked to the KoGES cohort based on participants’ geocoded residential addresses in grids of 1 km (particulate matter) or 9 km (gaseous air pollutants and meteorological variables). As the integrated data become available to all researchers, this resource is expected to serve as a useful infrastructure for research on the health effects of air pollution.
Summary
Korean summary
대기오염이 건강에 미치는 정도를 파악하고 이를 최소화하는 과학적 근거 생산 마련을 위하여 한국인유전체역학조사사업(KoGES) 자료와 대기오염 및 기상 자료를 연계하여 연구 기반을 마련하고자 하였다. 배출량, 기상자료 및 공기의 확산 등을 고려하는 화학수송모델(CMAQ)을 통하여 2005년에서 2017년 사이의 대기오염 및 기상자료를 예측하였으며, 이후 관측소 자료 및 인공위성자료인 에어로졸 광화학두께(AOD)를 추가 적용하여 최종 생산하였다. 미세먼지 자료는 1 km 격자로 기체상 오염물질 및 기상 자료는 9 km 격자 단위로 구성되었다. 생산된 자료는 KoGES 참여자의 주소를 기반으로 연계하여 최종 KoGES-대기오염 연계DB를 구축하였으며, 구축된 자료를 이용하여 KoGES 참여자의 대기오염 노출 수준을 공간적 시간적 분포로 살펴보았다. 구축된 자료는 내외부 연구자에게 공개가 되고 있어 대기오염에 의한 건강영향평가 및 피해를 최소화하는 방안 마련 연구를 위한 좋은 기반 자료가 될 것으로 기대된다.
Key Message
The Korean Genome and Epidemiology Study (KoGES) cohort were linked to air pollution data as a national resource for studying air pollution and its health effect. Air pollution data (2005~2017) were produced using community multiscale air quality modeling with additional adjustment of monitoring data, satellite-derived aerosol optical depth, normalized difference vegetation index, and meteorological data to increase the accuracy and spatial resolution. The modelled air pollution data were linked to the cohort based on participants’ geocoded residential addresses in grids of 1 km (particulate matter) or 9 km (gaseous air pollutants and meteorological variables).

Citations

Citations to this article as recorded by  
  • Association between short-term exposure to ambient air pollutants and biomarkers indicative of inflammation and oxidative stress: a cross-sectional study using KoGES-HEXA data
    Ji Hyun Kim, Hae Dong Woo, Jane J Lee, Dae Sub Song, Kyoungho Lee
    Environmental Health and Preventive Medicine.2024; 29: 17.     CrossRef
  • Exposure to ambient air pollution mixture and senescence-associated secretory phenotype proteins among middle-aged and older women
    Eunseon Gwak, Ji-Won Shin, Sun Young Kim, Jong Tae Lee, Ok Hee Jeon, Seung-Ah Choe
    Environmental Research.2024; : 119642.     CrossRef
  • Edible mushroom intake and risk of all-cause and cause-specific mortality: results from the Korean Genome and Epidemiology Study (KoGES) Cohort
    Hyein Jung, JiAe Shin, Kyungjoon Lim, Sangah Shin
    Food & Function.2023; 14(19): 8829.     CrossRef
  • Association between ambient particulate matter levels and hypertension: results from the Korean Genome and Epidemiology Study
    Sewhan Na, Jong-Tae Park, Seungbeom Kim, Jinwoo Han, Saemi Jung, Kyeongmin Kwak
    Annals of Occupational and Environmental Medicine.2023;[Epub]     CrossRef
The Korea National Health and Nutrition Examination Survey data linked Cause of Death data
Sungha Yun, Kyungwon Oh
Epidemiol Health. 2022;44:e2022021.   Published online February 9, 2022
DOI: https://doi.org/10.4178/epih.e2022021
  • 15,326 View
  • 703 Download
  • 10 Web of Science
  • 9 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea National Health and Nutrition Examination Survey (KNHANES) is a national health survey that is conducted annually to assess the health and and health-related behaviors of Korean population. To utilize KNHANES data to studies of mortality risk factors, the Korea Disease Control and Prevention Agency (KDCA) constructed a database linking KNHANES data to cause-of-death statistics in Statistics Korea, made available to researchers since 2020. The KNHANES data were linked to the Cause of Death Statistics based on resident registration numbers for subjects aged 19 years or older who agreed to link the data. The linkage rate between 2007-2015 National Health and Nutrition Examination Survey and 2007-2019 Cause of Death Statistics was 97.1%. In the linked dataset, the total death rate was 6.6%, of which neoplasms accounted for the highest death rate (32.1%), followed by circulatory system disease (22.7%) and respiratory system disease (11.5%). The linked dataset was made available through the Research Data Center of the KDCA after a review of the research proposal, and will be made available after periodical updates.
Summary
Korean summary
1. 국민건강영양조사 자료가 사망 위험요인 규명 연구에 활용되도록 통계청의 사망원인통계와 연계자료 구축함 2. 2007~2015년 국민건강영양조사와 2007~2019년 사망원인통계의 연계율은 97.1%이었음 3. 국민건강영양조사-사망원인통계 연계자료는 2020년부터 연구자에게 질병관리청 내 학술연구자료처리실를 통해 제공되고 있음
Key Message
1. To utilize the Korea National Health and Nutrition Examination Survey (KNHANES) data to studies of mortality risk factors, the data were linked to the Cause of Death Statistics in the Statistics Korea. 2. The linkage rate between the 2007-2015 KNHANES and the 2007-2019 Cause of Death Statistics was 97.1%. 3. The Korea National Health and Nutrition Examination Survey data linked Cause of Death data have been provided to researchers through the Research Data Center in the Korea Disease Control and Prevention Agency (KDCA) since 2020.

Citations

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  • Chronic Disease Patterns and Their Relationship With Health-Related Quality of Life in South Korean Older Adults With the 2021 Korean National Health and Nutrition Examination Survey: Latent Class Analysis
    Mi-Sun Lee, Hooyeon Lee
    JMIR Public Health and Surveillance.2024; 10: e49433.     CrossRef
  • Toloese Generates Nitric Oxide through Natural Radiation of Far Infrared Rays, Reducing Serum Glucose, Cholesterol, and Triglycerides
    Min-Ho Yeo, Young-Hyeon Lee, Mi-Jin Ryu, Yong-Hak Choi, Hye-Sook Kim, Kyung-Soo Chang
    Healthcare.2024; 12(12): 1227.     CrossRef
  • Computational method of the cardiovascular diseases classification based on a generalized nonlinear canonical decomposition of random sequences
    Igor Atamanyuk, Yuriy Kondratenko, Valerii Havrysh, Yuriy Volosyuk
    Scientific Reports.2023;[Epub]     CrossRef
  • The Association between Advanced Liver Fibrosis and Mortality Is Modified by Dietary Quality among Korean Adults: Results from the Korea National Health and Nutrition Examination Survey with Mortality Data
    Juhee Lee, Garam Jo, Dahyun Park, Hee Ju Jun, Jae Hyun Bae, Min-Jeong Shin
    Nutrients.2023; 15(6): 1501.     CrossRef
  • Association of dietary sodium intake with impaired fasting glucose in adult cancer survivors: A population-based cross-sectional study
    Kyuwoong Kim, Hamee Kim, Tae Joon Jun, Young-Hak Kim, Dong Keon Yon
    PLOS ONE.2023; 18(5): e0286346.     CrossRef
  • Fibrosis-4 Index Predicts Long-Term All-Cause, Cardiovascular and Liver-Related Mortality in the Adult Korean Population
    Young-Gyun Seo, Stergios A. Polyzos, Kyung-Hee Park, Christos S. Mantzoros
    Clinical Gastroenterology and Hepatology.2023; 21(13): 3322.     CrossRef
  • The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study
    Jae Yeol Kim, Jae-Woo Jung, Min-Jong Kang, Deog Kyeom Kim, Hayoung Choi, Young-Jae Cho, Seung Hun Jang, Chang-Hoon Lee, Yeon Mok Oh, Ji Sook Park
    The Korean Journal of Internal Medicine.2023; 38(5): 714.     CrossRef
  • The Korea Cohort Consortium: The Future of Pooling Cohort Studies
    Sangjun Lee, Kwang-Pil Ko, Jung Eun Lee, Inah Kim, Sun Ha Jee, Aesun Shin, Sun-Seog Kweon, Min-Ho Shin, Sangmin Park, Seungho Ryu, Sun Young Yang, Seung Ho Choi, Jeongseon Kim, Sang-Wook Yi, Daehee Kang, Keun-Young Yoo, Sue K. Park
    Journal of Preventive Medicine and Public Health.2022; 55(5): 464.     CrossRef
  • Self-perceived Weight and Mortality in Korean Adults Based on the Korea National Health and Nutrition Examination Survey Data Linked to Cause of Death Statistics
    Kayoung Lee
    Journal of Obesity & Metabolic Syndrome.2022; 31(4): 313.     CrossRef
Data resource profile: the Korea National Hospital Discharge In-depth Injury Survey
Yeon-Kyeng Lee, Sung Ok Hong, Soo-Jung Park, Mijin Park, Kyunghae Wang, Mini Jo, Jeongah Oh, Sin Ae Lee, Hyeon Ju Lee, Jungeun Oh, Dosang Lim, Sanghui Kweon, Youngtaek Kim
Epidemiol Health. 2021;43:e2021052.   Published online August 17, 2021
DOI: https://doi.org/10.4178/epih.e2021052
  • 9,913 View
  • 114 Download
  • 7 Web of Science
  • 7 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
The Korea National Hospital Discharge In-depth Injury Survey (KNHDIS), which was started in 2005, is a national probability survey of general hospitals in Korea with 100 or more beds conducted by the Korea Disease Control and Prevention Agency (KDCA). The KNHDIS captures approximately 9% of discharged cases from sampled hospitals using a 2-stage stratified cluster sampling scheme, among which 13% are injury related cases, defined as S00-T98 (injury, poisoning, and certain other consequences of external causes) using International Classification of Diseases, 10th revision codes. The KNHDIS collects information on characteristics of injury-related discharges in order to understand the scale of injuries, identify risk factors, and provide data supporting prevention policies and intervention strategies. The types of data captured include the hospitals’ information, detailed clinical information, and injury-related codes such as the mechanism, activities undertaken when injured (sports, leisure activities, work, treatment, and education), external causes of the injury, and location of the occurrence of the injury based on the International Classification of External Causes of Injuries. Furthermore, the means of transportation, risk factors for suicide, and toxic substances are recoreded. Annual reports of the KNHDIS are publicly accessible to browse via the KDCA website (http://www.kdca.go.kr) and microdata are available free of charge upon request via email (kcdcinjury@korea.kr).
Summary
Korean summary
퇴원손상심층조사는 손상발생 규모 및 손상 퇴원환자의 발생 추이를 파악하고자 2005년 도입된국가 단위 통계를 산출하는 표본 조사 사업이다. 본 연구는 퇴원손상심층조사의 표본설계, 조사방법, 조사항목과 함께 그간의 조사결과의 활용도 등 성과에 대해 살펴보았다. 조사결과는 국가 손상예방관리를 위한 기초자료로 활용되고 있으며, 조사 원자료는 공개하고 있다.
Key Message
The Korea National Hospital Discharge In-depth Injury Survey (KNHDIS), started in 2005, is a national probability survey of general hospitals in Korea with 100 or more beds conducted by the Korea Disease Control and Prevention Agency. The KNHDIS collects information on characteristics of injury-related discharges to understand the scale of injuries, identify risk factors, and provide data supporting prevention policies. The data captured including the hospitals’ information, and injury-related codes based on the International Classification of External Causes of Injuries. Annual reports of the KNHDIS are publicly accessible from KDCA website and microdata are available upon request via email.

Citations

Citations to this article as recorded by  
  • Temporal trends and the association between self-rated oral health and falls in community-dwelling older adults in South Korea: a secondary analysis of survey data
    Hyun-Ju Seo, Soon-Ki Ahn, Min-Jung Choi
    BMJ Open.2024; 14(4): e081549.     CrossRef
  • Assessing Trends in Hospitalizations for Breast Cancer among Women in Korea: A Utilization of the Korea National Hospital Discharge In-depth Injury Survey (2006–2020)
    Jieun Hwang, Jeong-Hoon Jang
    Journal of Epidemiology and Global Health.2024; 14(2): 411.     CrossRef
  • Predictive model for early functional outcomes following acute care after traumatic brain injuries: A machine learning-based development and validation study
    Meng Zhang, Moning Guo, Zihao Wang, Haimin Liu, Xue Bai, Shengnan Cui, Xiaopeng Guo, Lu Gao, Lingling Gao, Aimin Liao, Bing Xing, Yi Wang
    Injury.2023; 54(3): 896.     CrossRef
  • Area-Level Socioeconomic Inequalities in Intracranial Injury-Related Hospitalization in Korea: A Retrospective Analysis of Data From Korea National Hospital Discharge Survey 2008–2015
    Hang A Park, Federico E. Vaca, Kyunghee Jung-Choi, Hyesook Park, Ju Ok Park
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Comorbidity Patterns and Management in Inpatients with Endocrine Diseases by Age Groups in South Korea: Nationwide Data
    Sung-Soo Kim, Hun-Sung Kim
    Journal of Personalized Medicine.2023; 14(1): 42.     CrossRef
  • Estimated trends in hospitalizations due to occupational injuries in Korea based on the Korean National Hospital Discharge In-depth Injury Survey (2006-2019)
    Seonguk Baek, Won-Tae Lee, Min-Seok Kim, Myeong-Hun Lim, Jin-Ha Yoon
    Epidemiology and Health.2023; : e2023042.     CrossRef
  • The Association between Comorbidities and Comorbid Injuries on Treatment Outcome in Pediatric and Elderly Patients with Injuries in Korea: An Observational Study
    Kyunghee Lee, Jieun Hwang
    International Journal of Environmental Research and Public Health.2022; 19(10): 6277.     CrossRef
Establishment of the Korea National Health and Nutrition Examination Survey air pollution study dataset for the researchers on the health impact of ambient air pollution
Myung-Jae Hwang, Jisun Sung, Miryoung Yoon, Jong-Hun Kim, Hui-Young Yun, Dae-Ryun Choi, Youn-Seo Koo, Kyungwon Oh, Sungha Yun, Hae-Kwan Cheong
Epidemiol Health. 2021;43:e2021015.   Published online February 8, 2021
DOI: https://doi.org/10.4178/epih.e2021015
  • 15,280 View
  • 400 Download
  • 6 Web of Science
  • 7 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
To provide a nationwide representative dataset for the study on health impact of air pollution, we combined the data from the Korea National Health and Nutrition Examination Survey with the daily air quality and weather data by matching the date of examination and the residential address of the participants. The database of meteorological factors and air quality as sources of exposure data were estimated using the Community Multiscale Air Quality model. The linkage dataset was merged by three ways; administrative district, <i>si-gun-gu</i> (city, county, and district), and geocode (in latitude and longitude coordinate units) based on the participants’ residential address, respectively. During the study period, the exposure dataset of 85,018 individuals (38,306 men and 46,712 women) whose examination dates were recorded were obtained. According to the definition of exposure period, the dataset was combined with the data on short-term, mid-term, and long-term exposure to air pollutants and the meteorological indices. Calculation of the daily merged dataset’s average air pollution linked by <i>si-gun-gu</i> and geocode units showed similar results. This study generated a daily average of meteorological indices and air pollution exposure dataset for all regions including rural and remote areas in Korea for 11 years. It is expected to provide a platform for the researchers studying the health impact of air pollution and climate change on the representative population and area, which may facilitate the establishment of local health care plans by understanding the residents’ health status at the local as well as national level.
Summary
Korean summary
-2007년부터 2017년까지 11년간 국민건강영양조사의 검진조사 대상자의 검진일자와 지리정보를 기준으로 85,018명에 대해 기상 및 대기오염 모델링 자료를 결합하여 조사 대상자의 거주지주소를 이용하여 시·군·구 단위와 주소 기반 위경도 좌표를 기준으로 각각 노출자료를 결합함. -대기오염의 단기노출, 중기노출, 장기노출의 건강영향을 평가하기 위해 지연효과(lag effect)를 적용하여 각 건강자료와 결합함. -기상 및 대기오염 모델링 자료와 연계된 국민건강영양조사의 활용을 위한 data profile을 제시함.
Key Message
-We built a dataset for air pollution research by combining meteorological and air pollution modeling data through CMAQ for 85,018 individuals based on the date of examination and geographic information of the Korea National Health and Nutrition Examination Survey participants for 11 years, from 2007 to 2017. -Each exposure data was combined based on si-gun-gu (city, county, and district) and geocode (in latitude and longitude coordinate units) based on the participants’ residential address. -To evaluate the health effects of short-, medium- and long-term air pollution exposure, the lag values of days, months, and years was applied and combined with each health data. -A data profile was presented for the Korea National Health and Nutrition Examination Survey linked to meteorological and air pollution modeling data.

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  • Joint effect of long-term exposure to ambient air pollution on the prevalence of chronic obstructive pulmonary disease using the Korea National Health and Nutrition Examination Survey 2010–2019
    Eunjin Kwon, Taiyue Jin, Young-Ah You, Byungmi Kim
    Chemosphere.2024; 358: 142137.     CrossRef
  • Associations between short-term exposure to air pollution and thyroid function in a representative sample of the Korean population
    Kyoung-Nam Kim, SoHyun Park, Junseo Choi, Il-Ung Hwang
    Environmental Research.2024; 252: 119018.     CrossRef
  • Association between short- and medium-term exposure to air pollutants and depressive episode using comprehensive air quality index among the population in South Korea
    Yohwan Lim, Yunseo Choi, Eunseok Kang, Yeojin Jeong, Jihyeon Park, Hyun Wook Han
    Journal of Affective Disorders.2024; 356: 307.     CrossRef
  • Association between ambient particulate matter levels and hypertension: results from the Korean Genome and Epidemiology Study
    Sewhan Na, Jong-Tae Park, Seungbeom Kim, Jinwoo Han, Saemi Jung, Kyeongmin Kwak
    Annals of Occupational and Environmental Medicine.2023;[Epub]     CrossRef
  • Effect of Short- to Long-Term Exposure to Ambient Particulate Matter on Cognitive Function in a Cohort of Middle-Aged and Older Adults: KoGES
    Jane J. Lee, Ji Hyun Kim, Dae Sub Song, Kyoungho Lee
    International Journal of Environmental Research and Public Health.2022; 19(16): 9913.     CrossRef
  • Long-Term Effects of Ambient Particulate and Gaseous Pollutants on Serum High-Sensitivity C-Reactive Protein Levels: A Cross-Sectional Study Using KoGES-HEXA Data
    Ji Hyun Kim, Hae Dong Woo, Sunho Choi, Dae Sub Song, Jung Hyun Lee, Kyoungho Lee
    International Journal of Environmental Research and Public Health.2022; 19(18): 11585.     CrossRef
  • Effects of exposure to ambient air pollution on pulmonary function impairment in Korea: the 2007-2017 Korea National Health and Nutritional Examination Survey
    Soo Beom Choi, Sungha Yun, Sun-Ja Kim, Yong Bum Park, Kyungwon Oh
    Epidemiology and Health.2021; 43: e2021082.     CrossRef
Data resource profile: the allergic disease database of the Korean National Health Insurance Service
Sunyong Yoo, Dong-Wook Kim, Young-Eun Kim, Jong Heon Park, Yeon-Yong Kim, Kyu-dong Cho, Mi-Ji Gwon, Jae-In Shin, Eun-Joo Lee
Epidemiol Health. 2021;43:e2021010.   Published online January 21, 2021
DOI: https://doi.org/10.4178/epih.e2021010
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Researchers have been interested in probing how the environmental factors associated with allergic diseases affect the use of medical services. Considering this demand, we have constructed a database, named the Allergic Disease Database, based on the National Health Insurance Database (NHID). The NHID contains information on demographic and medical service utilization for approximately 99% of the Korean population. This study targeted 3 major allergic diseases, including allergic rhinitis, atopic dermatitis, and asthma. For the target diseases, our database provides daily medical service information, including the number of daily visits from 2013 and 2017, categorized by patients’ characteristics such as address, sex, age, and duration of residence. We provide additional information, including yearly population, a number of patients, and averaged geocoding coordinates by <i>eup, myeon</i>, and <i>dong</i> district code (the smallest-scale administrative units in Korea). This information enables researchers to analyze how daily changes in the environmental factors of allergic diseases (e.g., particulate matter, sulfur dioxide, and ozone) in certain regions would influence patients’ behavioral patterns of medical service utilization. Moreover, researchers can analyze long-term trends in allergic diseases and the health effects caused by environmental factors such as daily climate and pollution data. The advantages of this database are easy access to data, additional levels of geographic detail, time-efficient data-refining and processing, and a de-identification process that minimizes the exposure of identifiable personal information. All datasets included in the Allergic Disease Database can be downloaded by accessing the National Health Insurance Service data sharing webpage (https://nhiss.nhis.or.kr).
Summary
Korean summary
알레르기질환DB는 환경적 변화와 의료이용 연관성 연구를 지원하기 위해 만들어진 누구나 다운로드 가능한 공개용DB이다. 알레르기질환DB는 한국 전국민의 사회인구학적 특성 및 의료이용 정보가 구축되어 있는 국민건강보험공단의 국민건강정보DB를 활용하여 구축되었다. 알레르기질환DB는 2013년~2017년 알레르기성 비염, 아토피, 천식 상병코드로 청구된 의료이용 정보를 제공하고 있으며, 이를 활용하여 특정 지역에 다양한 환경적 변화와 의료이용과의 연관성 연구 등에 활발히 활용될 것으로 기대된다.
Key Message
The Allergic Disease Database based on the National Health Insurance Data is constructed for analyzing how environmental factors affect the use of medical services. The database provides most Korean medical service information of allergic diseases, such as allergic rhinitis, atopic dermatitis, and asthma from 2013 and 2017. This information enables researchers to study how daily changes of environmental factors in certain regions would influence patients’ behavioral patterns of medical service utilization. Moreover, researchers can analyze the long-term trend of allergic diseases, and health effects caused by environmental factors such as daily climate and pollution data.

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  • Evaluation of the Regulatory Required Post-Authorization Safety Study for Propacetamol: Nested Case-Control and Case-Time-Control Studies
    Sungho Bea, Dongwon Yoon, Han Eol Jeong, Juhong Jung, Seung-Mok Park, Juhee Jeon, Young-Min Ye, Jae-Hyun Lee, Ju-Young Shin
    Yonsei Medical Journal.2024; 65(2): 120.     CrossRef
  • The relationship between exposure to environmental noise and risk of atopic dermatitis, asthma, and allergic rhinitis
    Yongho Lee, Seunghyun Lee, Seula Park, Seong-Kyu Kang, June-Hee Lee, Dong-Wook Lee, Won-Jun Choi, Wanhyung Lee
    Ecotoxicology and Environmental Safety.2023; 268: 115677.     CrossRef
  • Increased risk of cataract surgery in patients with allergic disease: a population based cohort study
    Ji-Sun Paik, Kyungdo Han, Gahee Nam, Sun-Kyoung Park, Ho Sik Hwang, Yoon Hong Chun, Kyung-Sun Na
    Scientific Reports.2022;[Epub]     CrossRef
Family tree database of the National Health Information Database in Korea
Yeon-Yong Kim, Hae-young Hong, Kyu-Dong Cho, Jong Heon Park
Epidemiol Health. 2019;41:e2019040.   Published online October 1, 2019
DOI: https://doi.org/10.4178/epih.e2019040
  • 13,700 View
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  • 6 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
We constructed the family tree database (DB) by using a new family code system that can logically express interpersonal family relationships and by comparing and complementing health insurance eligibility data and resident register data of the National Health Information Database (NHID). In the family tree DB, Parents and grandparents are matched for more than 95% of those who were born between 2010 and 2017. Codes for inverse relationships and extended relationships are generated using sequences of the three-digit basic family codes. The family tree DB contains variables such as sex, birth year, family relations, and degree of kinship (maximum of 4) between subjects and family members. Using the family tree DB, we find that prevalence rates of hypertension, diabetes, ischemic heart disease, cerebrovascular disease, and cancer are higher for those with family history. The family tree DB may omit some relationships due to incomplete past data, and some family relations cannot be uniquely determined because the source data only contain relationships between head and members of the household. The family tree DB is a part of the NHID, and researchers can submit requests for data on the website at http://nhiss.nhis.or.kr. Requested data will be provided after approval from the data service review board. However, the family tree DB can be limitedly provided for studies with high public value in order to maximize personal information protection.
Summary
Korean summary
가족관계도(family tree) DB는 건강보험공단이 보유하는 건강보험 가입자정보와 행정전산망 정보를 바탕으로 가공·구축된 자료다. 4촌까지의 가족 관계를 파악할 수 있으며, 세대주 중심의 관계코드가 아닌 개인 단위의 논리적 기호로 구성된 관계코드를 통해 촌수, 계통, 성별을 구분하도록 하였다. 이를 바탕으로 의학적, 사회정책적으로 다양한 연구가 가능하다.

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    Jae Young Kim, Sung-youn Chun, Hyunsun Lim, Tae Ik Chang
    Scientific Reports.2023;[Epub]     CrossRef
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    Seon‐Mi Kim, Yujin Jeong, Yae Lim Kim, Minjung Kang, Eunjeong Kang, Hyunjin Ryu, Yunmi Kim, Seung Seok Han, Curie Ahn, Kook‐Hwan Oh
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  • Genograma y árbol genealógico
    María Yanes-Rodríguez, María Concepción Cruz-Cánovas, Enrique José Gamero-de-Luna
    Medicina de Familia. SEMERGEN.2022; 48(3): 200.     CrossRef
  • National General Health Screening Program in Korea: history, current status, and future direction
    Dong Wook Shin, Juhee Cho, Jae Hyun Park, BeLong Cho
    Precision and Future Medicine.2022; 6(1): 9.     CrossRef
  • Clinical Study Using Healthcare Claims Database
    Jin-Su Park, Chan Hee Lee
    Journal of Rheumatic Diseases.2021; 28(3): 119.     CrossRef
  • Comparison between calcium channel blocker with angiotensin converting enzyme inhibitor or angiotensin II type 1 receptor blocker combination on the development of new-onset diabetes in hypertensive Korean patients
    Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Dong Oh Kang, Won Young Jang, Woohyeun Kim, Ju Yeol Baek, Woong Gil Choi, Tae Soo Kang, Jihun Ahn, Sang-Ho Park, Sung Hun Park, Ji Yeon Hong, Ji Young Park, Min-
    Journal of Diabetes & Metabolic Disorders.2020; 19(1): 405.     CrossRef
National Epidemiologic Survey of Thyroid cancer (NEST) in Korea
Chang-Mo Oh, Hyun-Joo Kong, Eunyang Kim, Hyejin Kim, Kyu-Won Jung, Sohee Park, Young-Joo Won
Epidemiol Health. 2018;40:e2018052.   Published online October 26, 2018
DOI: https://doi.org/10.4178/epih.e2018052
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AbstractAbstract PDF
Abstract
The Korea Central Cancer Registry conducted the National Epidemiologic Survey of Thyroid cancer (NEST) to investigate changes in the epidemiological and clinical characteristics of thyroid cancer patients between 1999 and 2008. The NEST was designed to collect representative samples of patients with thyroid cancer diagnosed in the years 1999, 2005, and 2008 using a proportionally stratified and systematic random sampling method. Among 42,891 participants diagnosed with thyroid cancer, 5,796 participants were included in the final study population. This survey collected information on diagnostic methods and date, route of diagnosis, prior medical history and history of thyroid-related disease, tumor, lymph node, metastasis and collaborative stage, and treatment. The NEST dataset was also linked to the cause-of-death database from Statistics Korea. The mean age of the study participants was 46.9 years. The ratio of men to women was 1:5.5. In the analysis of the histologic type of cancer, the proportion of papillary thyroid carcinoma showed an increasing trend (p<0.01). In contrast, the proportion of distant metastasis and the mean tumor size of thyroid cancers showed decreasing trends over time (p<0.01, respectively).
Summary

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  • Hashimoto Thyroiditis and Mortality in Patients with Differentiated Thyroid Cancer: The National Epidemiologic Survey of Thyroid Cancer in Korea and Meta-Analysis
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    Endocrinology and Metabolism.2024; 39(2): 310.     CrossRef
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The current status of health data on Korean children and adolescents
Eunyoung Lee, Dahye Baik, Yoon Park, Moran Ki
Epidemiol Health. 2017;39:e2017059.   Published online December 26, 2017
DOI: https://doi.org/10.4178/epih.e2017059
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Childhood and adolescence are critical periods that affect adults’ health status. Therefore, the factors influencing the health of children and adolescents should be analyzed. In Korea, a wide range of youth-related health data has been obtained, both on the regional level and on the national level. This report summarizes the current status of studies related to the health of Korean children and adolescents. Data for which open access is offered include the Korea Youth Risk Behavior Web-based Study, the Panel Study on Korean Children, the Korean Youth Panel Survey, the Korean Children and Youth Panel Survey, and the Student Health Examination. In addition, the Health Examination of Korean Youth Outside of School, the Korean Children and Adolescents Obesity Cohort Study, the Korean Children’s Environmental Health Study, the Korea Youth Media Use and Harmful Environment Survey, the Comprehensive Survey of Korean Youth, and the Multicultural Adolescents Panel Study are summarized.
Summary
Korean summary
청소년시기는 성인의 건강상태에 영향을 미치는 중요한 시기이다. 따라서 청소년의 건강에 영향을 미치는 여러 가지 요소들에 대한 분석이 필요하다. 한국에서 청소년건강과 관련한 데이터는 지역 단위에서뿐 아니라 국가 단위에서도 수집되고 있다. 해당 데이터가 공개되고 있는 것으로는 청소년건강행태온라인조사, 한국아동패널, 한국청소년패널조사, 한국아동ㆍ청소년패널조사, 학교건강검사가 있다. 이외에도 학교 밖 청소년 건강검진조사, 소아비만 및 대사질환 코호트, 어린이 환경 보건 출생코호트, 청소년 매체이용 및 유해환경 실태조사, 청소년 종합실태조사, 다문화청소년패널조사를 요약하였다.

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  • Dietary intake and nutritional status of Korean children and adolescents: a review of national survey data
    Minji Kang, So Yoon Choi, Minyoung Jung
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  • Benefits of cooperation among large-scale cohort studies and human biomonitoring projects in environmental health research: An exercise in blood lead analysis of the Environment and Child Health International Birth Cohort Group
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National Infectious Diseases Surveillance data of South Korea
Sunhee Park, Eunhee Cho
Epidemiol Health. 2014;36:e2014030.   Published online November 11, 2014
DOI: https://doi.org/10.4178/epih/e2014030
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea Centers for Disease Control and Prevention (KCDC) operate infectious disease surveillance systems to monitor national disease incidence. Since 1954, Korea has collected data on various infectious diseases in accordance with the Infectious Disease Control and Prevention Act. All physicians (including those working in Oriental medicine) who diagnose a patient with an infectious disease or conduct a postmortem examination of an infectious disease case are obliged to report the disease to the system. These reported data are incorporated into the database of the National Infectious Disease Surveillance System, which has been providing web-based real-time surveillance data on infectious diseases since 2001. In addition, the KCDC analyzes reported data and publishes the Infectious Disease Surveillance Yearbook annually.
Summary
Korean summary
감염병웹통계(http://is.cdc.go.kr)에서는 전수감시 대상 54종 감염병에 대한지역별, 성별, 연령별, 감염지역별, 기간별, 전년대비 주간 발생현황 등 실시간 기간 검색이 가능하며, 검색된 통계를 표 또는 다양한 그래프로 볼 수 있으며, 또한 이러한 자료들은 엑셀로 다운로드하여 사용이 가능하다. 표본감시 대상 24종 감염병의 통계도 제공되고 있다.

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National Infectious Diseases Surveillance data of South Korea
Korean J Epidemiol. 2014;e2014030.   Published online November 11, 2014
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AbstractAbstract
Abstract
The Korea Centers for Disease Control and Prevention (KCDC) operate infectious disease surveillance systems to monitor national disease incidence. Since 1954, Korea has collected data on various infectious diseases in accordance with the Infectious Disease Control and Prevention Act. All physicians (including those working in oriental medicine) who diagnose a patient with an infectious disease or conduct a postmortem examination of an infectious disease case are obliged to report the disease to the system. These reported data are incorporated into the database of the National Infectious Disease Surveillance System (NIDSS), which has been providing web-based real-time surveillance data on infectious diseases since 2001. In addition, the KCDC analyzes reported data and publishes the Infectious Disease Surveillance Yearbook annually.
Summary
A guide for the utilization of Health Insurance Review and Assessment Service National Patient Samples
Logyoung Kim, Jee-Ae Kim, Sanghyun Kim
Epidemiol Health. 2014;36:e2014008.   Published online July 30, 2014
DOI: https://doi.org/10.4178/epih/e2014008
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AbstractAbstract PDFSupplementary Material
Abstract
The claims data of the Health Insurance Review and Assessment Service (HIRA) is an important source of information for healthcare service research. The claims data of HIRA is collected when healthcare service providers submit a claim to HIRA to be reimbursed for a service that they provided to patients. To improve the accessibility of healthcare service researchers to claims data of HIRA, HIRA has developed the Patient Samples which are extracted using a stratified randomized sampling method. The Patient Samples of HIRA consist of five tables: a table for general information (Table 20) containing socio-demographic information such as gender, age and medical aid, indicators for inpatient and outpatient services; a table for specific information on healthcare services provided (Table 30); a table for diagnostic information (Table 40); a table for outpatient prescriptions (Table 53) and a table for information on healthcare service providers (Table of providers). Researchers who are interested in using the Patient Sample data for research can apply via HIRA’s website (https://www.hira.or.kr).
Summary

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    Medicina.2023; 59(9): 1505.     CrossRef
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    Yonsei Medical Journal.2023; 64(9): 549.     CrossRef
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    Journal of Pain Research.2023; Volume 16: 3197.     CrossRef
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    Intestinal Research.2023; 21(4): 500.     CrossRef
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    Korean Journal of Clinical Pharmacy.2023; 33(3): 168.     CrossRef
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    Modern Rheumatology.2022; 32(1): 149.     CrossRef
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    The World Journal of Men's Health.2022; 40(3): 481.     CrossRef
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    The Journal of Arthroplasty.2021; 36(2): 542.     CrossRef
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    Suhyun Jang, Sohyun Jeong, Eunjeong Kang, Sunmee Jang
    Pharmacoepidemiology and Drug Safety.2021; 30(1): 17.     CrossRef
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    Yunjung Choi, Chang Hun Lee, In Hee Kim, Eun Hae Park, SoJeong Park, Wan-Hee Yoo
    Clinical Rheumatology.2021; 40(5): 2037.     CrossRef
  • Underutilization of gastrointestinal prophylaxis in high-risk chronic nonsteroidal anti-inflammatory drug users in Korea
    Woo-Youn Kim, Suhyun Lee, Kwanghee Jun, Young-Mi Ah, Ju-Yeun Lee
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  • Chronic obstructive pulmonary disease research by using big data
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    The Clinical Respiratory Journal.2021; 15(3): 257.     CrossRef
  • Trends in Pediatric Meningitis in South Korea during 2009 to 2017: Analysis of the Health Insurance Review and Assessment Service Database
    Jin Woo Kim, Soo Ahn Chae, Su Yeong Kim, Na Mi Lee, Dae Yong Yi, Sin Weon Yun, In Seok Lim
    Annals of Child Neurology.2021; 29(1): 30.     CrossRef
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    Young-Joon Kang, Se Jeong Oh, Hoon Choi, Shijin Cho, Chang-Hyun Shin, Chaiwon Kim, Joohyun Woo, JungSun Lee, Heung Kyu Park, Han-Byoel Lee, Woo Chul Noh, Yong-Seok Kim
    Breast Cancer Research and Treatment.2021; 186(1): 125.     CrossRef
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    Joint Bone Spine.2021; 88(3): 105128.     CrossRef
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    Dongwon Yoon, Ji-Ho Lee, Hyesung Lee, Ju-Young Shin
    BMJ.2021; : m4931.     CrossRef
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    Bon San Koo, Yu-Cheol Lim, Min-Young Lee, Ja-Young Jeon, Hyun-Jeong Yoo, In-Sun Oh, Ju-Young Shin, Tae-Hwan Kim
    Modern Rheumatology.2021; 31(6): 1192.     CrossRef
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    Young‐Sun Min, Sungho Lee, Mingi Kim, Yeon‐Soon Ahn
    American Journal of Industrial Medicine.2021; 64(4): 245.     CrossRef
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    Seong Min Oh, Kyung-Lak Son, Seok-Jin Choi, Mi Hyun Lee, So Young Yoon, Yu Jin Lee
    Journal of Clinical Sleep Medicine.2021; 17(5): 1051.     CrossRef
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  • Epidemiological characteristics of cancers in patients with end-stage kidney disease: a Korean nationwide study
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    Jung Ho Kim, Jiyeon Suh, Woon Ji Lee, Heun Choi, Jong-Dae Kim, Changsoo Kim, Jun Yong Choi, Ryeojin Ko, Heewon Kim, Jeehyun Lee, Joon Sup Yeom
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    Hankil Lee, Beom Kyung Kim, Sungin Jang, Sang Hoon Ahn
    Clinical and Translational Gastroenterology.2021; 12(2): e00299.     CrossRef
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    Mo-Yeol Kang, Jiyoun Jung, Jung-Wan Koo, Inah Kim, Hyoung-Ryoul Kim, Jun-Pyo Myong
    The Korean Journal of Internal Medicine.2021; 36(Suppl 1): S18.     CrossRef
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    Eileen L Yoon, Jin-Sung Yuk
    The Journal of Clinical Endocrinology & Metabolism.2021; 106(6): 1773.     CrossRef
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    Korean Journal of Clinical Pharmacy.2021; 31(1): 35.     CrossRef
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    Journal of Breast Cancer.2021; 24(3): 280.     CrossRef
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    International Journal of Environmental Research and Public Health.2021; 18(15): 8152.     CrossRef
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    Healthcare.2021; 9(10): 1304.     CrossRef
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    Medicine.2021; 100(40): e27439.     CrossRef
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    Journal of Clinical Medicine.2021; 10(20): 4647.     CrossRef
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    Allergy, Asthma & Immunology Research.2021; 13(6): 908.     CrossRef
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    Clinical & Experimental Thrombosis and Hemostasis.2021; 7(1): 14.     CrossRef
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    Journal of Retina.2021; 6(2): 84.     CrossRef
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    Healthcare.2021; 10(1): 7.     CrossRef
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    Journal of the Neurological Sciences.2021; 420: 117212.     CrossRef
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    Psychiatry Research.2021; 298: 113744.     CrossRef
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    Expert Review of Pharmacoeconomics & Outcomes Research.2020; 20(1): 139.     CrossRef
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    Clinical Pharmacology & Therapeutics.2020; 107(3): 530.     CrossRef
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  • Update on the prevalence and incidence of rheumatoid arthritis in Korea and an analysis of medical care and drug utilization
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  • The prevalence and treatment pattern of clinically diagnosed pelvic organ prolapse: a Korean National Health Insurance Database-based cross-sectional study 2009–2015
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  • Incidence of venous thromboembolism in Korea from 2009 to 2013
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  • Integrating and analyzing medical and environmental data using ETL and Business Intelligence tools
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    International Journal of Biometeorology.2018; 62(6): 1085.     CrossRef
  • The incidence of unexpected uterine malignancy in women undergoing hysteroscopic myomectomy or polypectomy: A national population-based study
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    European Journal of Obstetrics & Gynecology and Reproductive Biology.2018; 224: 12.     CrossRef
  • Measuring the effect of nurse staffing on patient outcomes: A comment on Kim & Bae (2018)
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    International Journal of Nursing Studies.2018; 82: 11.     CrossRef
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  • Nationwide Epidemiologic Study of Atypical Antipsychotic Use Among Pediatric Population with Mental Illness in Korea
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  • Tuberculosis infection via the emergency department among inpatients in South Korea: a propensity-score matched analysis of the National Inpatient Sample
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  • Administration of oral fluoroquinolone and the risk of rhegmatogenous retinal detachment: A nationwide population-based study in Korea
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  • Estimation of cost savings between 2011 and 2014 attributed to infliximab biosimilar in the South Korean healthcare market: real‐world evidence using a nationwide database
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    International Journal of Rheumatic Diseases.2018; 21(6): 1227.     CrossRef
  • Osteoporosis and fracture after gastrectomy for stomach cancer
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    Medicine.2018; 97(17): e0532.     CrossRef
  • Temporal relationship between antibiotic use and respiratory virus activities in the Republic of Korea: a time-series analysis
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  • The prevalence of primary hyperparathyroidism in Korea: a population-based analysis from patient medical records
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    International Journal of Medical Informatics.2018; 116: 1.     CrossRef
  • Impact of the Health Insurance Coverage Policy on Oral Anticoagulant Prescription among Patients with Atrial Fibrillation in Korea from 2014 to 2016
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  • Cumulative Dose Threshold for the Chemopreventive Effect of Aspirin Against Gastric Cancer
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  • Hospital-Acquired Pneumonia among Inpatients via the Emergency Department: A Propensity-Score Matched Analysis
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  • Incidence of Adhesive Bowel Obstruction After Colon Cancer Surgery and its Risk Factors
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  • Rethinking the Role of the Public Health Clinic: Comparison of Outpatient Utilization in the Public Health Clinics and Private Clinics in Korea
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  • Breast reconstruction statistics in Korea from the Big Data Hub of the Health Insurance Review and Assessment Service
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  • Association networks in a matched case-control design – Co-occurrence patterns of preexisting chronic medical conditions in patients with major depression versus their matched controls
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  • Building Linked Big Data for Stroke in Korea: Linkage of Stroke Registry and National Health Insurance Claims Data
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  • Identification of target risk groups for population-based Clostridium difficile infection prevention strategies using a population attributable risk approach
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  • Is cupping therapy effective in patients with neck pain? A systematic review and meta-analysis
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  • Evaluation of the predictors of readmission in Korean patients with heart failure
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  • Safety of resuming biologic DMARDs in patients who develop tuberculosis after anti-TNF treatment
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  • Health Care Utilization and Direct Costs in Mild, Moderate, and Severe Adult Asthma: A Descriptive Study Using the 2014 South Korean Health Insurance Database
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  • Participation inequality in the National General Health Examination based on enterprise size
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  • Epidemiology of Chronic Urticaria in Korea Using the Korean Health Insurance Database, 2010-2014
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  • Prescription Trends of Psychotropics in Children and Adolescents with Autism Based on Nationwide Health Insurance Data
    Minha Hong, Seung Yup Lee, Juhee Han, Jin Cheol Park, Yeon Jung Lee, Ram Hwangbo, Hyejung Chang, Seong Woo Cho, Soo-Young Bhang, Bongseog Kim, Jun-Won Hwang, Geon Ho Bahn
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  • Seasonal Cycle and Relationship of Seasonal Rhino- and Influenza Virus Epidemics With Episodes of Asthma Exacerbation in Different Age Groups
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  • Analysis of medical service use of knee osteoarthritis and knee meniscal and ligament injuries in Korea: a cross-sectional study of national patient sample data
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  • The Use Pattern and Clinical Impact of New Antiplatelet Agents Including Prasugrel and Ticagrelor on 30-day Outcomes after Acute Myocardial Infarction in Korea: Korean Health Insurance Review and Assessment Data
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    Evidence-Based Complementary and Alternative Medicine.2017; 2017: 1.     CrossRef
  • A national pharmacoepidemiological study of antibiotic use in Korean paediatric outpatients
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  • Warfarin Use in Patients With Atrial Fibrillation Undergoing Hemodialysis
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  • Medical service use and usual care of common shoulder disorders in Korea: a cross-sectional study using the Health Insurance Review and Assessment Service National Patient Sample
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  • Comparison of Survival Outcomes in Women with Unsuspected Uterine Malignancy Diagnosed After Laparotomic Versus Laparoscopic Myomectomy: A National, Population-Based Study
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  • The Clinical Status of Radiation Therapy in Korea in 2009 and 2013
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  • Graves Disease Is Associated With Endometriosis
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  • Higher prevalence of dementia in patients with schizophrenia: A nationwide population‐based study
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    Asia-Pacific Psychiatry.2016; 8(2): 145.     CrossRef
  • Utilization of Western and Traditional Korean Medicine for Children and Adolescents with Mental Disorders: a Nationwide Population-based Study from 2010 to 2012
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  • Network analysis of human diseases using Korean nationwide claims data
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  • Analysis of Surgical Pathology Data in the HIRA Database: Emphasis on Current Status and Endoscopic Submucosal Dissection Specimens
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  • The Incidence of Unexpected Uterine Malignancy in Women Undergoing Hysterectomy for a Benign Condition: A National Population-Based Study
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  • Association between pregnancy and adnexal torsion
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  • Incidence and Risk Factors Associated With Hospitalization for Variant Angina in Korea
    Hack-Lyoung Kim, Sang Hyung Lee, Jayeun Kim, Hyun Joo Kim, Woo-Hyun Lim, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim, Jin Yong Lee
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  • Incidence, Survival and Prevalence Statistics of Classical Myeloproliferative Neoplasm in Korea
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  • The incidence rates of endometrial hyperplasia and endometrial cancer: a four-year population-based study
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  • Risk of hospitalization for hypoglycemia among older Korean people with diabetes mellitus
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  • Prevalence and socio-economic burden of heart failure in an aging society of South Korea
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  • The Diagnostic Distribution of Psychiatric Disorders among the Population Under 19 Years Old: Based on the National Insurance Data
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  • Finding the Primary Care Providers in the Specialist-Dominant Primary Care Setting of Korea: A Cluster Analysis
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  • National trends in carotid endarterectomy and stenting in Korea from 2004 to 2013
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  • National trends for open and endovascular repair of aneurysms in Korea: 2004-2013
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  • Evaluation of use and cost of medical care of common lumbar disorders in Korea: cross-sectional study of Korean Health Insurance Review and Assessment Service National Patient Sample data
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  • Rapid Increase of Health Care Utilization and Cost due to Benign Prostatic Hyperplasia in Korean Men: Retrospective Population-based Analysis Using the Health Insurance Review and Assessment Service Data
    Hwancheol Son, Juhyun Park, Sang Hoon Song, Jung Yoon Kang, Sung Kyu Hong, Hyun Moo Lee, Sun-Hee Kim, Byung-Joo Park, Hyung-Lae Lee, Kyung Seop Lee
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  • Unexpected uterine malignancy in women who have undergone myomectomy
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    International Journal of Gynecology & Obstetrics.2015; 129(3): 270.     CrossRef
  • High rate of nickel allergy in women with endometriosis: A 3‐year population‐based study
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  • Difference in Healthcare Utilization for Percutaneous Transluminal Coronary Angioplasty Inpatients by Insurance Types: Propensity Score Matching Analysis
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    Health Policy and Management.2015; 25(1): 3.     CrossRef
  • Correlation between Drug Market Withdrawals and Socioeconomic, Health, and Welfare Indicators Worldwide
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  • Frontal Lobe Function and Risk of Hip Fracture in Patient With Alzheimer Disease
    Hyun Woong Roh, Chang Hyung Hong, SooJin Lee, Yunhwan Lee, Kang Soo Lee, Ki Jung Chang, Byoung Hoon Oh, Seong Hye Choi, Seong Yoon Kim, Joung Hwan Back, Young Ki Chung, Ki Young Lim, Jai Sung Noh, Sang Joon Son
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  • National trends for the treatment of peripheral arterial disease in Korea between 2004 and 2013
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  • Diabetes Mellitus and Site-specific Colorectal Cancer Risk in Korea: A Case-control Study
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  • Association between Aspirin Therapy and Clinical Outcomes in Patients with Non-Obstructive Coronary Artery Disease: A Cohort Study
    In-Chang Hwang, Joo-Yeong Jeon, Younhee Kim, Hyue Mee Kim, Yeonyee E. Yoon, Seung-Pyo Lee, Hyung-Kwan Kim, Dae-Won Sohn, Jidong Sung, Yong-Jin Kim, Michael J Lipinski
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  • Co-Medication of Statins with Contraindicated Drugs
    Bo Ram Yang, Jong-Mi Seong, Nam-Kyong Choi, Ju-Young Shin, Joongyub Lee, Ye-Jee Kim, Mi-Sook Kim, Soyoung Park, Hong Ji Song, Byung-Joo Park, Stephan Henrik Schirmer
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