Epidemiology and Health

Mohammad Ali Mansournia

8 Articles

The effects of water-pipe smoking on birth weight: a population-based prospective cohort study in southern Iran: Shahrzad Nematollahi, Mohammad Ali Mansournia, Abbas Rahimi Foroushani, Mahmood Mahmoodi, Azin Alavi, Mohammad Shekari, Kourosh Holakouie-Naieni; Epidemiol Health. 2018;40:e2018008. Published online March 13, 2018; DOI: https://doi.org/10.4178/epih.e2018008

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Abstract

OBJECTIVES
Consecutive community health assessments revealed that water-pipe smoking in women and impaired growth in children were among the main health concerns in suburban communities in southern Iran. The aim of the present study was to identify the effects of water-pipe smoking during pregnancy on birth weight.

METHODS

Data from a population-based prospective cohort study of 714 singleton live pregnancies in the suburbs of Bandar Abbas in southern Iran in 2016-2018 were used in this study. Data about water-pipe smoking patterns and birth weight were collected by questionnaires during and after the pregnancy. Low birth weight (LBW) was defined as a birth weight below 2,500 g. Statistical analyses were performed using generalized linear models, and the results were presented in terms of relative risk (RR) and 95% confidence intervals (CI).

RESULTS

Fifty (8.2%) of the study subjects smoked water-pipe. The adjusted risk of LBW increased 2-fold in water-pipe smokers (adjusted RR [aRR], 2.09; 95% CI, 1.18 to 3.71), and by 2.0% for each 1-year increase in the duration of water-pipe smoking (aRR, 1.02; 95% CI, 0.99 to 1.05).

CONCLUSIONS

Our results showed that water-pipe smoking during pregnancy was an important risk factor for LBW in this population sample from southern Iran. The introduction of regulations onto prevent water-pipe smoking and the implementation of community health action plans aiming at empowering women and increasing women’s knowledge and awareness regarding the health consequences of water-pipe smoking are proposed.

Summary

Citations

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The Diversity in Tobacco Use Among Women of Reproductive Age (15–49 Years) in Pakistan: A Secondary Analysis of a Multiple Indicator Cluster Survey 2016–2018
Radha Sharma, Mona Kanaan, Kamran Siddiqi
Nicotine and Tobacco Research.2024; 26(7): 931. CrossRef
Sevrage tabagique au cours de la grossesse
V. Peyronnet, A.-L. Le Faou, I. Berlin
Revue des Maladies Respiratoires.2024; 41(9): 685. CrossRef
Waterpipe Tobacco (Hookah) Use in Pregnancy: Associations with Nausea and Vomiting of Pregnancy
Anna R. Whelan, Alexis C. Gimovsky, Nancy C. Jao, Erika F. Werner, Chrystal Vergara-Lopez, Laura R. Stroud
American Journal of Perinatology.2023; 40(10): 1033. CrossRef
Interventions for waterpipe smoking cessation
Taghrid Asfar, Jonathan Livingstone-Banks, Kenneth D Ward, Thomas Eissenberg, Olusanya Oluwole, Zoran Bursac, Tarek Ghaddar, Wasim Maziak
Cochrane Database of Systematic Reviews.2023;[Epub] CrossRef
Dual and Poly Use of Tobacco Products in a Sample of Pregnant Smokers: A Cross-sectional Study
André Luís Bertani, Suzana Erico Tanni, Irma Godoy
Maternal and Child Health Journal.2023; 27(9): 1616. CrossRef
Reproductive outcomes of water pipe smoking: A scoping review
Sahar Rostami, Farzane Fereidouni, Arezoo Maleki-Hajiagha, Mohadese Motaharinejad, Somayye Majidi, Fardin Amidi
Asian Pacific Journal of Reproduction.2023; 12(5): 211. CrossRef
What are the intervention goals of women’s hookah cessation? A systematic, evidence-based and participatory study
Sakineh Dadipoor, Teamur Aghamolaei, Mehdi Mirzaei-Alavijeh, Mohtasham Ghaffari, Ali Heyrani, Saeed Hosseini Teshnizi
Journal of Ethnicity in Substance Abuse.2022; 21(4): 1468. CrossRef
Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020
Hong-Kun Di, Yong Gan, Kai Lu, Chao Wang, Yi Zhu, Xin Meng, Wen-Qi Xia, Min-Zhi Xu, Jing Feng, Qing-Feng Tian, Yan He, Zhi-Qiang Nie, Jun-An Liu, Fu-Jian Song, Zu-Xun Lu
World Journal of Pediatrics.2022; 18(3): 176. CrossRef
Using intervention mapping for hookah smoking cessation: a quasi-experimental evaluation
Sakineh Dadipoor, Ali Heyrani, Mehdi Mirzaei-Alavijeh, Teamur Aghamolaei, Mohtasham Ghaffari, Amin Ghanbarnejad
Addiction Science & Clinical Practice.2022;[Epub] CrossRef
Association Between a History of Hookah Use and Breastfeeding Duration
Zelalem T. Haile, Ilana R. Azulay Chertok, Mohammad Rifat Haider
Breastfeeding Medicine.2022; 17(8): 678. CrossRef
Waterpipe Tobacco Smoke Exposure during Lactation—Susceptibility of Reproductive Hormones and Oxidative Stress Parameters in Male Progeny Rats
Nour A. Al-Sawalha, Indira D. Pokkunuri, Karem H. Alzoubi, Omar F. Khabour, Bashar N. Almomani
Reproductive Sciences.2021; 28(1): 37. CrossRef
Trends of maternal waterpipe, cigarettes, and dual tobacco smoking in Jordan. A decade of lost opportunities
Khalid A. Kheirallah, Nuha Shugaa Addin, Maan M. Alolimat, Eman Sobh
PLOS ONE.2021; 16(7): e0253655. CrossRef
Effect of Water-Pipe Smoking on the Normal Development of Zebrafish
Zain Zaki Zakaria, Shaima Ahmad Aladwi, Fatiha Benslimane, Enas S. Al-Absi, Mashael Al-Shafai, Huseyin C. Yalcin, Ashraf Khalil, Ala-Eddin Al Moustafa, Maha Al-Asmakh
International Journal of Environmental Research and Public Health.2021; 18(21): 11659. CrossRef
An intervention development for cessation of hookah smoking among Iranian women: study protocol for a systematic and theory-based approach to intervention design
Sakineh Dadipoor, Gerjo Kok, Ali Heyrani, Teamur Aghamolaei, Mohtasham Ghaffari, Amin Ghanbarnezhad
Addiction Science & Clinical Practice.2020;[Epub] CrossRef
The effect of quitting water pipe during pregnancy on anthropometric measurements at birth: a population-based prospective cohort study in the south of Iran
Shahrzad Nematollahi, Koroush Holakouie-Naieni, Abdolhossain Madani, Hossein Shabkhiz, Elham Torabi, Samane Lotfi
BMC Pregnancy and Childbirth.2020;[Epub] CrossRef
Autres méthodes de consommation pendant la grossesse : cigarette électronique, tabac chauffé, chicha et snus — Rapport d’experts et recommandations CNGOF-SFT sur la prise en charge du tabagisme en cours de grossesse
C. Garabedian, P. Berveiller, P. Guerby
Gynécologie Obstétrique Fertilité & Sénologie .2020; 48(7-8): 583. CrossRef
Predictors of Hookah Smoking among Women in Bandar Abbas, Southern Iran: A Cross-Sectional Study Based on the Intervention Mapping Protocol
Sakineh Dadipoor, Ali Heyrani, Teamur Aghamolaei, Amin Ghanbarnezhad, Mohtasham Ghaffari
Substance Use & Misuse.2020; 55(11): 1800. CrossRef
Potential causes of male and female infertility in Qatar
Gerhild Zauner, Guillermina Girardi
Journal of Reproductive Immunology.2020; 141: 103173. CrossRef
Waterpipe smoking: the pressing need for risk communication
Wasim Maziak, Olatokunbo Osibogun, Taghrid Asfar
Expert Review of Respiratory Medicine.2019; 13(11): 1109. CrossRef
Epidemiology and Adverse Consequences of Hookah/Waterpipe Use: A Systematic Review
Rebecca Pratiti, Debabrata Mukherjee
Cardiovascular & Hematological Agents in Medicinal Chemistry .2019; 17(2): 82. CrossRef

Associations between dietary risk factors and ischemic stroke: a comparison of regression methods using data from the Multi-Ethnic Study of Atherosclerosis: Seyed Saeed Hashemi Nazari, Yaser Mokhayeri, Mohammad Ali Mansournia, Soheila Khodakarim, Hamid Soori; Epidemiol Health. 2018;40:e2018021. Published online May 21, 2018; DOI: https://doi.org/10.4178/epih.e2018021

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Abstract PDF

Abstract

OBJECTIVES
We analyzed dietary patterns using reduced rank regression (RRR), and assessed how well the scores extracted by RRR predicted stroke in comparison to the scores produced by partial least squares and principal component regression models.

METHODS

Dietary data at baseline were used to extract dietary patterns using the 3 methods, along with 4 response variables: body mass index, fibrinogen, interleukin-6, and low-density lipoprotein cholesterol. The analyses were based on 5,468 males and females aged 45-84 years who had no clinical cardiovascular disease, using data from the Multi-Ethnic Study of Atherosclerosis.

RESULTS

The primary factor derived by RRR was positively associated with stroke incidence in both models. The first model was adjusted for sex and race and the second model was adjusted for the variables in model 1 as well as smoking, physical activity, family and sibling history of stroke, the use of any lipid-lowering medication, the use of any anti-hypertensive medication, hypertension, and history of myocardial infarction (model 1: hazard ratio [HR], 7.49; 95% confidence interval [CI], 1.66 to 33.69; p for trend=0.01; model 2: HR, 6.83; 95% CI, 1.51 to 30.87 for quintile 5 compared with the reference category; p for trend=0.02).

CONCLUSIONS

Based primarily on RRR, we identified that a dietary pattern high in fats and oils, poultry, non-diet soda, processed meat, tomatoes, legumes, chicken, tuna and egg salad, and fried potatoes and low in dark-yellow and cruciferous vegetables may increase the incidence of ischemic stroke.

Summary

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Trimethylamine N-oxide, β-alanine, tryptophan index, and vitamin B6-related dietary patterns in association with stroke risk
Dong Liu, Siyue Tan, Zhengyuan Zhou, Shujun Gu, Hui Zuo
Nutrition, Metabolism and Cardiovascular Diseases.2024; 34(5): 1179. CrossRef
A comparison of principal component analysis, reduced-rank regression, and partial least–squares in the identification of dietary patterns associated with cardiometabolic risk factors in Iranian overweight and obese women
Fatemeh Gholami, Ahmadreza Hajiheidari, Bahareh Barkhidarian, Neda Soveid, Mir Saeid Yekaninejad, Zahra Karimi, Niki Bahrampour, Seyed Ali Keshavarz, Gholamali Javdan, Khadijeh Mirzaei
BMC Medical Research Methodology.2024;[Epub] CrossRef
Comparison of data-driven identified hypertension-protective dietary patterns among Chinese adults: based on a nationwide study
Yuxiang Yang, Wei Piao, Shuya Cai, Kun Huang, Changzheng Yuan, Xue Cheng, Ling Zhang, Yuge Li, Liyun Zhao, Dongmei Yu
European Journal of Nutrition.2023; 62(7): 2805. CrossRef
Associations between dietary patterns and cardiovascular disease risk in Canadian adults: a comparison of partial least squares, reduced rank regression, and the simplified dietary pattern technique
Svilena V Lazarova, Mahsa Jessri
The American Journal of Clinical Nutrition.2022; 116(2): 362. CrossRef
Association Between Dietary Quality Indices and Atherosclerosis Risk: A Case-Control Study
Mahsa Samadani, Anahita Mansoori, Habib Haybar, Fatemeh Haidari, Majid Mohammadshahi
Nutrition and Metabolic Insights.2022;[Epub] CrossRef
Visceral adiposity-related dietary patterns and the risk of cardiovascular disease in Iranian adults: A population-based cohort study
Nazanin Moslehi, Fatemeh Rahimi Sakak, Maryam Mahdavi, Parvin Mirmiran, Fereidoun Azizi
Frontiers in Nutrition.2022;[Epub] CrossRef
Dietary patterns derived by reduced rank regression and non-communicable disease risk
Carmen Piernas, Min Gao, Susan A. Jebb
Proceedings of the Nutrition Society.2022; : 1. CrossRef
Dietary patterns related to cardiovascular disease based on reduced rank regression analysis of healthy middle-aged Koreans: data from the community-based Korean Genome and Epidemiology Study (KoGES) cohort
Hye Ah Lee, Hyoin An, EunJin Lee
The American Journal of Clinical Nutrition.2020; 111(6): 1159. CrossRef
Interaction between an ATP-Binding Cassette A1 (ABCA1) Variant and Egg Consumption for the Risk of Ischemic Stroke and Carotid Atherosclerosis: a Family-Based Study in the Chinese Population
Jing Song, Xia Jiang, Yaying Cao, Juan Juan, Tao Wu, Yonghua Hu
Journal of Atherosclerosis and Thrombosis.2019; 26(9): 835. CrossRef

Exploring neighborhood inequality in female breast cancer incidence in Tehran using Bayesian spatial models and a spatial scan statistic: Erfan Ayubi, Mohammad Ali Mansournia, Ali Ghanbari Motlagh, Alireza Mosavi-Jarrahi, Ali Hosseini, Kamran Yazdani; Epidemiol Health. 2017;39:e2017021. Published online May 17, 2017; DOI: https://doi.org/10.4178/epih.e2017021

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Abstract PDF

Abstract

OBJECTIVES
The aim of this study was to explore the spatial pattern of female breast cancer (BC) incidence at the neighborhood level in Tehran, Iran.

METHODS

The present study included all registered incident cases of female BC from March 2008 to March 2011. The raw standardized incidence ratio (SIR) of BC for each neighborhood was estimated by comparing observed cases relative to expected cases. The estimated raw SIRs were smoothed by a Besag, York, and Mollie spatial model and the spatial empirical Bayesian method. The purely spatial scan statistic was used to identify spatial clusters.

RESULTS

There were 4,175 incident BC cases in the study area from 2008 to 2011, of which 3,080 were successfully geocoded to the neighborhood level. Higher than expected rates of BC were found in neighborhoods located in northern and central Tehran, whereas lower rates appeared in southern areas. The most likely cluster of higher than expected BC incidence involved neighborhoods in districts 3 and 6, with an observed-to-expected ratio of 3.92 (p<0.001), whereas the most likely cluster of lower than expected rates involved neighborhoods in districts 17, 18, and 19, with an observed-to-expected ratio of 0.05 (p<0.001).

CONCLUSIONS

Neighborhood-level inequality in the incidence of BC exists in Tehran. These findings can serve as a basis for resource allocation and preventive strategies in at-risk areas.

Summary

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An examination and analysis of the clustering of healthcare centers and their spatial accessibility in Tehran metropolis: Insights from Google POI data
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Sustainable Cities and Society.2024; 117: 105845. CrossRef
Clusters of high-risk, low-risk, and temporal trends of breast and cervical cancer-related mortality in São Paulo, Brazil, during 2000–2016
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Annals of Epidemiology.2023; 78: 61. CrossRef
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Revista Brasileira de Epidemiologia.2023;[Epub] CrossRef
Intra-urban spatial variability of breast and cervical cancer mortality in the city of São Paulo: analysis of associated factors
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The Effect of Religious–Spiritual Psychotherapy on Illness Perception and Inner Strength among Patients with Breast Cancer in Iran
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Journal of Religion and Health.2022; 61(6): 4302. CrossRef
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Mustafa Andkhoie, Michael Szafron
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Massimiliano Agovino, Massimiliano Cerciello, Gaetano Musella
Social Science & Medicine.2021; 287: 114328. CrossRef
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Yuwei Wang, Wang Gao
IOP Conference Series: Earth and Environmental Science.2020; 568(1): 012009. CrossRef
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Mohammad Khalid Hossain, Qingmin Meng
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Massimiliano Agovino, Maria Carmela Aprile, Antonio Garofalo, Angela Mariani
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Spatial modeling of cutaneous leishmaniasis in Iranian army units during 2014-2017 using a hierarchical Bayesian method and the spatial scan statistic
Erfan Ayubi, Mohammad Barati, Arasb Dabbagh Moghaddam, Ali Reza Khoshdel
Epidemiology and Health.2018; 40: e2018032. CrossRef

The association between physical activity and atrial fibrillation applying the Heaviside function in survival analysis: the Multi-Ethnic Study of Atherosclerosis: Yaser Mokhayeri, Seyed Saeed Hashemi-Nazari, Mohammad Ali Mansournia, Hamid Soori, Soheila Khodakarim; Epidemiol Health. 2017;39:e2017024. Published online June 18, 2017; DOI: https://doi.org/10.4178/epih.e2017024

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Abstract PDF

Abstract

OBJECTIVES
Although the effect of physical activity (PA) on the incidence of atrial fibrillation (AF) has been studied, contradictory results have been reported. Such discrepancies may reflect the different effects of various types of PA upon AF, as well as gender interactions. Therefore, we aimed to evaluate the associations of PA types (total, moderate/vigorous, and intentional), as well as walking pace, with AF risk in men and women.

METHODS

Using the Multi-Ethnic Study of Atherosclerosis Typical Week Physical Activity Survey, 3 PA measures and walking pace were calculated among 6,487 men and women aged 45-84 years. The incidence of AF over approximately 11 years of followup was ascertained. The association of each PA measure and walking pace with AF incidence was estimated using multivariable Cox proportional hazard models. An extended Cox model with Heaviside functions (hv) of time was used to estimate the effects of time-varying covariates.

RESULTS

During 11 years of follow-up (49,557 person-years), 242 new AF cases occurred. The incidence rate of AF was 48.83 per 10,000 person-years. The proportional hazard (PH) assumption for total PA among women was not met; hence, we used the hv to calculate the hazard ratio. Total PA in women in the hv2 analysis was negatively associated with AF in all 3 models, although for hv1 no significant association was observed. The PH assumption for walking pace among men was not met, and none of the hv showed a statistically significant association between walking pace and AF in men.

CONCLUSIONS

These results suggest that PA is inversely associated with AF in women.

Summary

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Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies
Asma Kazemi, Sepideh Soltani, Dagfinn Aune, Elham Hosseini, Zeinab Mokhtari, Zahra Hassanzadeh, Ahmad Jayedi, Francisco Pitanga, Masoumeh Akhlaghi
International Journal of Behavioral Nutrition and Physical Activity.2024;[Epub] CrossRef
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International Journal of Cardiology.2023; 370: 191. CrossRef
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Associations between diabetes self-management and microvascular complications in patients with type 2 diabetes: Fatemeh Mehravar, Mohammad Ali Mansournia, Kourosh Holakouie-Naieni, Ensie Nasli-Esfahani, Nasrin Mansournia, Amir Almasi-Hashiani; Epidemiol Health. 2016;38:e2016004. Published online January 25, 2016; DOI: https://doi.org/10.4178/epih.e2016004

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Abstract PDF

Abstract

OBJECTIVES
Diabetes is a major public health problem that is approaching epidemic proportions globally. Diabetes self-management can reduce complications and mortality in type 2 diabetic patients. The purpose of this study was to examine associations between diabetes self-management and microvascular complications in patients with type 2 diabetes.

METHODS

In this cross-sectional study, 562 Iranian patients older than 30 years of age with type 2 diabetes who received treatment at the Diabetes Research Center of the Endocrinology and Metabolism Research Institute of the Tehran University of Medical Sciences were identified. The participants were enrolled and completed questionnaires between January and April 2014. Patients’ diabetes self-management was assessed as an independent variable by using the Diabetes Self-Management Questionnaire translated into Persian. The outcomes were the microvascular complications of diabetes (retinopathy, nephropathy, and neuropathy), identified from the clinical records of each patient. A multiple logistic regression model was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) between diabetes self-management and the microvascular complications of type 2 diabetes, adjusting for potential confounders.

RESULTS

After adjusting for potential confounders, a significant association was found between the diabetes self-management sum scale and neuropathy (adjusted OR, 0.64; 95% CI, 0.45 to 0.92, p=0.01). Additionally, weak evidence was found of an association between the sum scale score of diabetes self-management and nephropathy (adjusted OR, 0.71; 95% CI, 0.47 to 1.05, p=0.09).

CONCLUSIONS

Among patients with type 2 diabetes, a lower diabetes self-management score was associated with higher rates of nephropathy and neuropathy.

Summary

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Assessing measurement error in surveys using latent class analysis: application to self-reported illicit drug use in data from the Iranian Mental Health Survey: Kazem Khalagi, Mohammad Ali Mansournia, Afarin Rahimi-Movaghar, Keramat Nourijelyani, Masoumeh Amin-Esmaeili, Ahmad Hajebi, Vandad Sharif, Reza Radgoodarzi, Mitra Hefazi, Abbas Motevalian; Epidemiol Health. 2016;38:e2016013. Published online April 10, 2016; DOI: https://doi.org/10.4178/epih.e2016013

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Abstract PDF: Abstract
Latent class analysis (LCA) is a method of assessing and correcting measurement error in surveys. The local independence assumption in LCA assumes that indicators are independent from each other condition on the latent variable. Violation of this assumption leads to unreliable results. We explored this issue by using LCA to estimate the prevalence of illicit drug use in the Iranian Mental Health Survey. The following three indicators were included in the LCA models: five or more instances of using any illicit drug in the past 12 months (indicator A), any use of any illicit drug in the past 12 months (indicator B), and the self-perceived need of treatment services or having received treatment for a substance use disorder in the past 12 months (indicator C). Gender was also used in all LCA models as a grouping variable. One LCA model using indicators A and B, as well as 10 different LCA models using indicators A, B, and C, were fitted to the data. The three models that had the best fit to the data included the following correlations between indicators: (AC and AB), (AC), and (AC, BC, and AB). The estimated prevalence of illicit drug use based on these three models was 28.9%, 6.2% and 42.2%, respectively. None of these models completely controlled for violation of the local independence assumption. In order to perform unbiased estimations using the LCA approach, the factors violating the local independence assumption (behaviorally correlated error, bivocality, and latent heterogeneity) should be completely taken into account in all models using well-known methods.; Summary

Adjusting for reverse causation to estimate the effect of obesity on mortality after incident heart failure in the Atherosclerosis Risk in Communities (ARIC) study: Maryam Shakiba, Hamid Soori, Mohammad Ali Mansournia, Seyed Saeed Hashemi Nazari, Yahya Salimi; Epidemiol Health. 2016;38:e2016025. Published online June 4, 2016; DOI: https://doi.org/10.4178/epih.e2016025

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Abstract PDF

Abstract

OBJECTIVES
The lower mortality rate of obese patients with heart failure (HF) has been partly attributed to reverse causation bias due to weight loss caused by disease. Using data about weight both before and after HF, this study aimed to adjust for reverse causation and examine the association of obesity both before and after HF with mortality.

METHODS

Using the Atherosclerosis Risk in Communities (ARIC) study, 308 patients with data available from before and after the incidence of HF were included. Pre-morbid and post-morbid obesity were defined based on body mass index measurements at least three months before and after incident HF. The associations of pre-morbid and post-morbid obesity and weight change with survival after HF were evaluated using a Cox proportional hazard model.

RESULTS

Pre-morbid obesity was associated with higher mortality (hazard ratio [HR], 1.61; 95% confidence interval [CI], 1.04 to 2.49) but post-morbid obesity was associated with increased survival (HR, 0.57; 95% CI, 0.37 to 0.88). Adjusting for weight change due to disease as a confounder of the obesity-mortality relationship resulted in the absence of any significant associations between post-morbid obesity and mortality.

CONCLUSIONS

This study demonstrated that controlling for reverse causality by adjusting for the confounder of weight change may remove or reverse the protective effect of obesity on mortality among patients with incident HF.

Summary

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Prevalence and clinical characteristics of diabetic cardiomyopathy in patients with acute heart failure
Kenichi Matsushita, Kazumasa Harada, Takashi Kohno, Hiroki Nakano, Daisuke Kitano, Junya Matsuda, Makoto Takei, Hideaki Yoshino, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
Nutrition, Metabolism and Cardiovascular Diseases.2024; 34(5): 1325. CrossRef
Impact of body mass index on cardiac adrenergic derangement in heart failure patients: a 123I-mIBG imaging study
Klara Komici, Leonardo Bencivenga, Stefania Paolillo, Paola Gargiulo, Roberto Formisano, Roberta Assante, Carmela Nappi, Fabio Marsico, Adriana D’Antonio, Giovanni De Simini, Antonio Cittadini, Dino Franco Vitale, Alberto Cuocolo, Pasquale Perrone Filardi
European Journal of Nuclear Medicine and Molecular Imaging.2020; 47(7): 1713. CrossRef
Impact of prior bariatric surgery on outcomes of hospitalized patients with heart failure: a population-based study
Hedong Han, Tiantian Zhu, Yibin Guo, Yiming Ruan, Eyal Herzog, Jia He
Surgery for Obesity and Related Diseases.2019; 15(3): 469. CrossRef
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Clinical Research in Cardiology.2019; 108(12): 1371. CrossRef
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American Journal of Epidemiology.2019; 188(10): 1838. CrossRef

Risk factors for amputation in patients with diabetic foot ulcer in southwest Iran: a matched case-control study: Mohammad Kogani, Mohammad Ali Mansournia, Amin Doosti-Irani, Kourosh Holakouie-Naieni; Epidemiol Health. 2015;37:e2015044. Published online October 5, 2015; DOI: https://doi.org/10.4178/epih/e2015044

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Abstract PDF

Abstract

OBJECTIVES
Amputation is a multifactorial complication in diabetic patients. The aim of this study was to determine the risk factors associated with amputation in patients with diabetic foot ulcers.

METHODS

This matched case-control study was conducted based on new cases of amputation from March 2012 to November 2014. We selected new cases who had undergone amputation, and the control group was chosen from the cities or areas where the cases resided. Each case was matched with two controls based on the duration of diabetes and location. Conditional logistic regression was used to evaluate the associations between potential risk factors and amputation.

RESULTS

A total of 131 cases were compared with 262 controls. The results of the adjusted model showed that sex (odds ratio [OR], 8.66; 95% confidence interval [CI], 2.68 to 27.91), fewer than two hemoglobin A1c (HbA1c) tests per year (OR, 13.97; 95% CI, 4.97 to 39.26), unsuitable shoes (OR, 5.50; 95% CI, 2.20 to 13.77), smoking (OR, 3.44; 95% CI, 1.45 to 8.13), and body mass index (OR, 1.20; 95% CI, 1.03 to 1.41) were associated with amputation in diabetic patients.

CONCLUSIONS

The most important factors associated with amputation were females, irregular monitoring of HbA1c levels, improper footwear, and smoking. Developing educational programs and working to ensure a higher quality of care for diabetic patients are necessary steps to address these issues.

Summary

Citations

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