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Korean Journal of Epidemiology 1985;7(1): 16-27.
일부 농촌지역 주민의 HBsAg 및 Anti-HBs 양성률과 간기능검사 결과와의 상관성에 관한 연구
김정순, 이원영, 이승욱, 윤희섭, 양숙자, 이두호, 김향철
An epidemiological study on HBsAg and anti-HBs prevalence in relation to liver function tests among farmers in Korea
Joung Soon Kim, Won Young Lee, S.W Lee, Hee Sup Yoon, Sook Ja Yang, D.H Lee, H.C. Kim
Abstract
This study was carried out in a rural area for the adult population older than 20 years of age to find out the prevalence of HBsAg and Anti-HBs among the population, and particularly the relationship between the presence of HBsAg and liver function tests during November 1984. Six hundred fourteen persons were interviewed according to structured questionnaire, examined by physician, and blood was drawn for the tests. For the detection of HBsAg and Anti-HBs Eliza method was used. The liver function test including SGOT, SGPT, alkaline phosphatase, total bilirubin and albumin was done in an university hospital laboratory of clinical pathology. The results summarized are as followings: 1. The prevalence rate of HBsAg positive was 13.0% and Anti-HBs positive was 43.6% among the population studied. The age adjusted positive rate by sex showed higher rate in males(14.6%) than females(12.7%) for HBsAg, whereas the positive rate was higher in females than males for anti-HBs although these differences by sex were not statistically significant (p〉0.05). 2. The age specific positive rate for both HBsAg and anti-HBs revealed peaks on 30~39 yrs. age group even though the Anti-HBs showed a slight increase for the age group older than 60 years. 3. The HBsAg positive rate was the highest (17.6%) among simple labourers accompanied by the highest positive rate of anti-HBs (58.8%) and then farmers, sales worker, clerical workers showed higher positive rate in order when the positive rates were compared by occupation. Also the lower socioeconomic class revealed higher positive rate. 4. The positive rates of both HBsAg and Anti-HBs were not different statistically between alcohol drinkers and non-drinkers, cigarette smokers and non-smokers, and the group with past history of liver disease and that without the history. 5. The HBsAg positive group when compared with HBsAg and Anti-HBs negative group showed 1.9 times more in family history of liver disease, 1.5 times in surgical operation, 1.4 times in blood transfusion. 6. The abnormal liver function test was found to be much more frequent among persons with past or present history of liver disease than those without; 84.2% versus 17.9%. By each item of the liver function test the HBsAg positive group had 1.6 times more abnormal value of bilirubin, 1.3 times of SGPT, and 1.2 times of SGPT than those who were negative for both HBsAg and Anti-HBs. The SGOT/SGPT ratio was not statistically different between two groups HBsAg positive and negative.


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