Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
1 "Transmission of infectious disease"
Filter
Filter
Article category
Keywords
Publication year
Authors
MERS-Epidemiologic Investigation
The first case of the 2015 Korean Middle East Respiratory Syndrome outbreak
Yong-Shik Park, Changhwan Lee, Kyung Min Kim, Seung Woo Kim, Keon-Joo Lee, Jungmo Ahn, Moran Ki
Epidemiol Health. 2015;37:e2015049.   Published online November 14, 2015
DOI: https://doi.org/10.4178/epih/e2015049
  • 17,640 View
  • 186 Download
  • 22 Web of Science
  • 28 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
This study reviewed problems in the prevention of outbreak and spread of Middle East Respiratory Syndrome (MERS) and aimed to provide assistance in establishing policies to prevent and manage future outbreaks of novel infectious diseases of foreign origin via in-depth epidemiological investigation of the patient who initiated the MERS outbreak in Korea, 2015. Personal and phone interviews were conducted with the patient and his guardians, and his activities in Saudi Arabia were investigated with the help of the Saudi Arabian Ministry of Health. Clinical courses and test results were confirmed from the medical records. The patient visited 4 medical facilities and contacted 742 people between May 11, 2015, at symptom onset, and May 20, at admission to the National Medical Center; 28 people were infected and diagnosed with MERS thereafter. Valuable lessons learned included: (1) epidemiological knowledge on the MERS transmission pattern and medical knowledge on its clinical course; (2) improvement of epidemiological investigative methods via closed-circuit television, global positioning system tracking, and review of Health Insurance Review and Assessment Service records; (3) problems revealed in the existing preventive techniques, including early determination of the various people contacted; (4) experiences with preventive methods used for the first time in Korea, including cohort quarantine; (5) reconsideration of the management systems for infectious disease outbreaks across the country, such as this case, at the levels of central government, local government, and the public; (6) reconsideration of hospital infectious disease management systems, culture involving patient visitation, and emergency room environments.
Summary
Korean summary
2015년 한국 메르스 유행의 발단이 된 첫 번째 환자의 역학조사를 통해 신종감염병의 국내 유입 경위 및 유행확산을 막기 위한 대응 과정의 문제점을 되짚어 보았다. 이를 통해 향후 신종감염병의 국내유입을 막기 위한 대비, 대응 정책 수립에 도움이 되길 바라며 이번 메르스 유행이 한국의 병원감염 관리 수준이 향상되는 계기가 되어야 할 것이다.

Citations

Citations to this article as recorded by  
  • Serosurvey for Middle East respiratory syndrome coronavirus antibody in dromedary camels and human patients at a secondary care hospital, Illela, Northwest Nigeria
    Samson Polycarp Salam, Grace Sabo Nok Kia, Faleke Olufemi Oladayo, Iniobong Chukwuebuka Ikenna Ugochukwu
    Comparative Clinical Pathology.2022; 31(3): 537.     CrossRef
  • Use of surveillance technology to enhance exposure management for healthcare workers during the COVID-19 pandemic
    H.J. Ho, W.Y. Lim, B. Ang, A. Chow
    Journal of Hospital Infection.2021; 107: 101.     CrossRef
  • Assessment of general awareness among Pakistani students regarding COVID-19 outbreak
    Tanveer Hussain, Usman Shah Gilani, Samea Khan, Syed Muhammad Muslim Raza
    Children and Youth Services Review.2021; 121: 105830.     CrossRef
  • Middle East Respiratory Syndrome (MERS) Virus—Pathophysiological Axis and the Current Treatment Strategies
    Abdullah M Alnuqaydan, Abdulmajeed G Almutary, Arulmalar Sukamaran, Brian Tay Wei Yang, Xiao Ting Lee, Wei Xuan Lim, Yee Min Ng, Rania Ibrahim, Thiviya Darmarajan, Satheeshkumar Nanjappan, Jestin Chellian, Mayuren Candasamy, Thiagarajan Madheswaran, Ankur
    AAPS PharmSciTech.2021;[Epub]     CrossRef
  • Knowledge, awareness and practices of Pakistani professionals amid-COVID-19 outbreak
    Samea Khan, Usman Shah Gilani, Syed Muhammad Muslim Raza, Tanveer Hussain
    Scientific Reports.2021;[Epub]     CrossRef
  • Surface‒Aerosol Stability and Pathogenicity of Diverse Middle East Respiratory Syndrome Coronavirus Strains, 2012‒2018
    Neeltje van Doremalen, Michael Letko, Robert J. Fischer, Trenton Bushmaker, Jonathan Schulz, Claude K. Yinda, Stephanie N. Seifert, Nam Joong Kim, Maged G. Hemida, Ghazi Kayali, Wan Beom Park, Ranawaka A.P.M. Perera, Azaibi Tamin, Natalie J. Thornburg, Su
    Emerging Infectious Diseases.2021; 27(12): 3052.     CrossRef
  • Middle East Respiratory Syndrome Coronavirus
    Jaffar A. Al-Tawfiq, Esam I. Azhar, Ziad A. Memish, Alimuddin Zumla
    Seminars in Respiratory and Critical Care Medicine.2021; 42(06): 828.     CrossRef
  • Super-spreading events and contribution to transmission of MERS, SARS, and SARS-CoV-2 (COVID-19)
    J.A. Al-Tawfiq, A.J. Rodriguez-Morales
    Journal of Hospital Infection.2020; 105(2): 111.     CrossRef
  • Is Pakistan prepared for the COVID‐19 epidemic? A questionnaire‐based survey
    Samea Khan, Mahjabeen Khan, Khizra Maqsood, Tanveer Hussain, Noor‐ul‐Huda, Muhammad Zeeshan
    Journal of Medical Virology.2020; 92(7): 824.     CrossRef
  • Use of a Real-Time Locating System for Contact Tracing of Health Care Workers During the COVID-19 Pandemic at an Infectious Disease Center in Singapore: Validation Study
    Hanley J Ho, Zoe Xiaozhu Zhang, Zhilian Huang, Aung Hein Aung, Wei-Yen Lim, Angela Chow
    Journal of Medical Internet Research.2020; 22(5): e19437.     CrossRef
  • Molecular Evolution and Structural Mapping of N-Terminal Domain in Spike Gene of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
    Asif Naeem, Maaweya Hamed, Majed Alghoribi, Waleed Aljabr, Hadel Alsaran, Mushira Enani, Bandar Alosaimi
    Viruses.2020; 12(5): 502.     CrossRef
  • Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis
    Yewei Xie, Zaisheng Wang, Huipeng Liao, Gifty Marley, Dan Wu, Weiming Tang
    BMC Infectious Diseases.2020;[Epub]     CrossRef
  • Healthcare-associated infections: the hallmark of Middle East respiratory syndrome coronavirus with review of the literature
    J.A. Al-Tawfiq, P.G. Auwaerter
    Journal of Hospital Infection.2019; 101(1): 20.     CrossRef
  • Middle East respiratory syndrome coronavirus intermittent positive cases: Implications for infection control
    Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Ziad A. Memish
    American Journal of Infection Control.2019; 47(3): 290.     CrossRef
  • Airflow analysis of Pyeongtaek St Mary's Hospital during hospitalization of the first Middle East respiratory syndrome patient in Korea
    Seongmin Jo, Jinkwan Hong, Sang-Eun Lee, Moran Ki, Bo Youl Choi, Minki Sung
    Royal Society Open Science.2019; 6(3): 181164.     CrossRef
  • Middle East respiratory syndrome coronavirus-encoded ORF8b strongly antagonizes IFN-β promoter activation: its implication for vaccine design
    Jeong Yoon Lee, Sojung Bae, Jinjong Myoung
    Journal of Microbiology.2019; 57(9): 803.     CrossRef
  • A database of geopositioned Middle East Respiratory Syndrome Coronavirus occurrences
    Rebecca E. Ramshaw, Ian D. Letourneau, Amy Y. Hong, Julia Hon, Julia D. Morgan, Joshua C. P. Osborne, Shreya Shirude, Maria D. Van Kerkhove, Simon I. Hay, David M. Pigott
    Scientific Data.2019;[Epub]     CrossRef
  • MERS-CoV infection in South Korea and strategies for possible future outbreak: narrative review
    Chulwoo Park
    Journal of Global Health Reports.2019;[Epub]     CrossRef
  • A study of the probable transmission routes of MERS-CoV during the first hospital outbreak in the Republic of Korea
    S. Xiao, Y. Li, M. Sung, J. Wei, Z. Yang
    Indoor Air.2018; 28(1): 51.     CrossRef
  • Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea
    Myoung-don Oh, Wan Beom Park, Sang-Won Park, Pyoeng Gyun Choe, Ji Hwan Bang, Kyoung-Ho Song, Eu Suk Kim, Hong Bin Kim, Nam Joong Kim
    The Korean Journal of Internal Medicine.2018; 33(2): 233.     CrossRef
  • Asymptomatic Middle East Respiratory Syndrome coronavirus infection using a serologic survey in Korea
    Yeong-jun Song, Jeong-Sun Yang, Hee Jung Yoon, Hae-Sung Nam, Soon Young Lee, Hae-Kwan Cheong, Woo-Jung Park, Sung Han Park, Bo Youl Choi, Sung Soon Kim, Moran Ki
    Epidemiology and Health.2018; 40: e2018014.     CrossRef
  • Airflow as a Possible Transmission Route of Middle East Respiratory Syndrome at an Initial Outbreak Hospital in Korea
    Minki Sung, Seongmin Jo, Sang-Eun Lee, Moran Ki, Bo Choi, JinKwan Hong
    International Journal of Environmental Research and Public Health.2018; 15(12): 2757.     CrossRef
  • Surveys and Proposals of the Infectious Disease Home Isolation through Middle East Respiratory Syndrome (MERS) Transmission
    Song Yi An, Woong Jung, Chang Min Lee, Sung Hyuk Park, Hyun Kyung Park, Myung Chun Kim
    Korean Journal of Healthcare-Associated Infection Control and Prevention.2018; 23(2): 72.     CrossRef
  • Identified Transmission Dynamics of Middle East Respiratory Syndrome Coronavirus Infection During an Outbreak: Implications of an Overcrowded Emergency Department
    Thamer H. Alenazi, Hussain Al Arbash, Aiman El-Saed, Majid M. Alshamrani, Henry Baffoe-Bonnie, Yaseen M. Arabi, Sameera M. Al Johani, Ra’ed Hijazi, Adel Alothman, Hanan H. Balkhy
    Clinical Infectious Diseases.2017; 65(4): 675.     CrossRef
  • The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2015
    Ji Yeon Lee, You-Jin Kim, Eun Hee Chung, Dae-Won Kim, Ina Jeong, Yeonjae Kim, Mi-ran Yun, Sung Soon Kim, Gayeon Kim, Joon-Sung Joh
    BMC Infectious Diseases.2017;[Epub]     CrossRef
  • Extensive Viable Middle East Respiratory Syndrome (MERS) Coronavirus Contamination in Air and Surrounding Environment in MERS Isolation Wards
    Sung-Han Kim, So Young Chang, Minki Sung, Ji Hoon Park, Hong Bin Kim, Heeyoung Lee, Jae-Phil Choi, Won Suk Choi, Ji-Young Min
    Clinical Infectious Diseases.2016; 63(3): 363.     CrossRef
  • Outbreaks of Middle East Respiratory Syndrome in Two Hospitals Initiated by a Single Patient in Daejeon, South Korea
    Sun Hee Park, Yeon-Sook Kim, Younghee Jung, Soo young Choi, Nam-Hyuk Cho, Hye Won Jeong, Jung Yeon Heo, Ji Hyun Yoon, Jacob Lee, Shinhye Cheon, Kyung Mok Sohn
    Infection & Chemotherapy.2016; 48(2): 99.     CrossRef
  • Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection
    Anurodh Shankar Agrawal, Tianlei Ying, Xinrong Tao, Tania Garron, Abdullah Algaissi, Yanping Wang, Lili Wang, Bi-Hung Peng, Shibo Jiang, Dimiter S. Dimitrov, Chien-Te K. Tseng
    Scientific Reports.2016;[Epub]     CrossRef

Epidemiol Health : Epidemiology and Health