Epidemiology and Health

COVID-19: Original Article

The anatomy of COVID-19 comorbidity networks among hospitalized Korean patients: Eun Kyong Shin, Hyo Young Choi, Neil Hayes; Epidemiol Health. 2021;43:e2021035. Published online May 7, 2021; DOI: https://doi.org/10.4178/epih.e2021035

11,164 View
381 Download
3 Web of Science
3 Crossref

Abstract

OBJECTIVES
We aimed to examine how comorbidities were associated with outcomes (illness severity or death) among hospitalized patients with coronavirus disease 2019 (COVID-19).

METHODS

Data were provided by the National Medical Center of the Korea Disease Control and Prevention Agency. These data included the clinical and epidemiological information of all patients hospitalized with COVID-19 who were discharged on or before April 30, 2020 in Korea. We conducted comorbidity network and multinomial logistic regression analyses to identify risk factors associated with COVID-19 disease severity and mortality. The outcome variable was the clinical severity score (CSS), categorized as mild (oxygen treatment not needed), severe (oxygen treatment needed), or death.

RESULTS

In total, 5,771 patients were included. In the fully adjusted model, chronic kidney disease (CKD) (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.19 to 5.61) and chronic obstructive pulmonary disease (COPD) (OR, 3.19; 95% CI, 1.35 to 7.52) were significantly associated with disease severity. CKD (OR, 5.35; 95% CI, 2.00 to 14.31), heart failure (HF) (OR, 3.15; 95% CI, 1.22 to 8.15), malignancy (OR, 3.38; 95% CI, 1.59 to 7.17), dementia (OR, 2.62; 95% CI, 1.45 to 4.72), and diabetes mellitus (OR, 2.26; 95% CI, 1.46 to 3.49) were associated with an increased risk of death. Asthma and hypertension showed statistically insignificant associations with an increased risk of death.

CONCLUSIONS

Underlying diseases contribute differently to the severity of COVID-19. To efficiently allocate limited medical resources, underlying comorbidities should be closely monitored, particularly CKD, COPD, and HF.

Summary

Korean summary
본 연구는 2019 년 코로나 바이러스 질환 (COVID-19)으로 입원 한 환자의 합병증이 결과 (질병 중증도 또는 사망)와 어떤 관련이 있는지를 동반 질환 네트워크 및 다항 로지스틱 회귀 분석을 통해 분석하였다. 기저 질환은 COVID-19의 중증도 및 사망에 차별적으로 영향을 미친다. 제한된 의료 자원을 효율적으로 활용하기 위해서 환자의 기저 동반 질환 중, 특히 만성 신장 질환 (CKD), 만성 폐쇄성 폐 질환 (COPD), 심부전 (HF)을 더욱 면밀히 모니터링해야 한다.

Key Message
We examined how comorbidities were associated with outcomes (illness severity or death) among hospitalized patients with coronavirus disease 2019 (COVID-19), implementing comorbidity network and multinomial logistic regression analyses. Underlying diseases contribute differently to the severity of COVID-19. To efficiently allocate limited medical resources, underlying comorbidities should be closely monitored, particularly chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD), and heart failure (HF).

Citations

Citations to this article as recorded by

SARS-CoV-2 susceptibility and COVID-19 illness course and outcome in people with pre-existing neurodegenerative disorders: systematic review with frequentist and Bayesian meta-analyses
Muhannad Smadi, Melina Kaburis, Youval Schnapper, Gabriel Reina, Patricio Molero, Marc L. Molendijk
The British Journal of Psychiatry.2023; 223(2): 348. CrossRef
Asthma and COPD as co-morbidities in patients hospitalised with Covid-19 disease: a global systematic review and meta-analysis
James Patrick Finnerty, A. B. M. Arad Hussain, Aravind Ponnuswamy, Hafiz Gulzeb Kamil, Ammar Abdelaziz
BMC Pulmonary Medicine.2023;[Epub] CrossRef
The Role of Diabetes and Hyperglycemia on COVID-19 Infection Course—A Narrative Review
Evangelia Tzeravini, Eleftherios Stratigakos, Chris Siafarikas, Anastasios Tentolouris, Nikolaos Tentolouris
Frontiers in Clinical Diabetes and Healthcare.2022;[Epub] CrossRef

Original Articles

Correlation between depressive symptoms and subjective mastication ability and ability to pronunciation among Korean elderly: Min Sun Park, Kyung-Gyun Hwang, Bo Youl Choi; Epidemiol Health. 2016;38:e2016035. Published online July 25, 2016; DOI: https://doi.org/10.4178/epih.e2016035

16,373 View
233 Download
5 Web of Science
5 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The present study examines the relationship between depressive symptoms and subjective chewing and pronunciation ability in Korean seniors. Our goal is to provide the data required to develop appropriate oral health interventions programs for seniors.

METHODS

The Center for Epidemiologic Studies-Depression Scale (CES-D) is widely used depressive symptoms assessment. A Korean version was used for the 2009 Community Health Survey, which was consulted to extract the present study’s participants comprising 50,694 Korean seniors (males, 20,582; females, 30,112) aged ≥65 years. Those with a CES-D score ≥16 were rated ‘depressed.’ SAS version 9.3 was used for the data analysis.

RESULTS

Prevalence of depressive symptoms increased as the participants socioeconomic status decreased, number of health issues increased, health behavior worsened, and chewing and pronunciation discomfort increased. Males with chewing difficulties were found to have 1.45 times (95% confidence interval [CI], 1.29 to 1.63) greater risk of depressive symptoms than those without, while males with pronunciation discomfort were found to have 1.97 times greater risk of depressive symptoms than those without (95% CI, 1.76 to 2.20). Females with chewing difficulty were found to have 1.50 times (95% CI, 1.39 to 1.61) greater risk of depressive symptoms than those without, and females with pronunciation discomfort were found to have 1.55 times greater risk of depressive symptoms than those without (95% CI, 1.44 to 1.67).

CONCLUSIONS

Intervention programs designed to help with oral health management and alleviate depressive symptoms in seniors are urgently needed. As the prevalence of depressive symptoms may vary geographically, research examining potential variance at city, district, and town levels would be beneficial.

Summary

Korean summary
The Center for Epidemiologic Studies-Depression Scale(CES-D)을 번역하여 조사된 2009년 지역사회건강조사 원시자료를 이용하여 전국 노인의 구강 보건 관리와 우울증상 관리를 중재하는 프로그램의 개발 및 접근에 있어 기초 자료를 제공하고자 하였다. 한국 노인의 주관적 구강저작능력과 발음능력상태와 우울증상은 인구 사회학적 특성, 건강수준 및 건강행태 관련 요인에 유의한 차이가 있었으며, 이에 따른 체계적이고 지속할 수 있는 중재프로그램의 기획 및 적용이 필요할 것으로 생각된다.

Citations

Citations to this article as recorded by

Association Between Changes in Oral Health-Related Quality of Life and Depressive Symptoms in the Korean Elderly Population
Kyoung Eun Park, Hooyeon Lee, Young Dae Kwon, Sukil Kim
International Journal of Public Health.2023;[Epub] CrossRef
Association and mediators between the impact of oral health‐related quality of life and depression
Tianjiao Xin, Fangfang Hu, Lingzhong Xu, Fanlei Kong, Haifeng Yang, Lei Li, Afei Qin, Binghong Bao, Chiqi Chen, Jing Lan
Oral Diseases.2023;[Epub] CrossRef
Effect of Anesthesia/Euthanasia Method Used for Brain Collection on GSK3β Activation in Male Sprague-Dawley Rats
Suryun Jung, Sooyeun Lee
Drug Targets and Therapeutics.2022; 1(1): 45. CrossRef
Oral health‐related quality of life is associated with the prevalence and development of depressive symptoms in older Japanese individuals: The Ohasama Study
Takashi Ohi, Takahisa Murakami, Takamasa Komiyama, Yoshitada Miyoshi, Kosei Endo, Takako Hiratsuka, Michihiro Satoh, Kei Asayama, Ryusuke Inoue, Masahiro Kikuya, Hirohito Metoki, Atsushi Hozawa, Yutaka Imai, Makoto Watanabe, Takayoshi Ohkubo, Yoshinori Ha
Gerodontology.2022; 39(2): 204. CrossRef
Association between subjective oral dysfunction and locomotive syndrome in community-dwelling older adults
Misa Nakamura, Masakazu Imaoka, Hidetoshi Nakao, Mitsumasa Hida, Fumie Tazaki, Ryota Imai, Hirotoshi Utsunomiya, Hiroshi Hashizume
Scientific Reports.2021;[Epub] CrossRef

Development of Stress Measurement Tools in Korean Dental Laboratory Technicians.: Ji Hwan Kim, Won Chul Lee, Kang Sook Lee, Chul Lee, Kinam Jin; Korean J Epidemiol. 2000;22(2):171-171.

5,344 View
20 Download

Abstract PDF: Abstract
PURPOSE
This study was performed to develop a proper self-administered survey instrument which can be used to measure psychiatric stress symptoms in Korean dental laboratory technicians, and to investigate the relationship between the symptom dimensions and stress inducing factors, such as psychological distress, stress inducing overload, work demand, work procedure and so forth in them.
METHODS
Prepared questionnaires were mailed to 1,000 dental laboratory technicians who were systematically selected. There were 786 responses to the questionnaires. All the data obtained were analyzed with SAS program.
RESULTS
Fifty items for the stress symptom checklist for dental technician(SCLD) were selected after a pilot test, interviews and literature reviews. Stress symptoms were classified into the following 6 categories, i.e, somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, and hostility symptom. Factor analysis for validity was carried out for corroboration, using the SCL-90-R as a standard.
CONCLUSION
SCLD had the reasonable reliability and validity. We believe that this study provides validity and reliability for new self-report questionnaire, it will make a significant contribution to assessment of stress symptoms.; Summary

First
Prev
Page of 1
Next
Last

Search