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Cardiovascular Risk Factors for Incident Hypertension in the Prehypertensive Population
Soo Jeong Kim, Jakyoung Lee, Sun Ha Jee, Chung Mo Nam, Kihong Chun, Il Soo Park, Soon Young Lee
Epidemiol Health. 2010;32:e2010003.   Published online May 1, 2010
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  • 19 Crossref
AbstractAbstract PDF
<sec><title>OBJECTIVES</title><p>The aim of this study was to investigate the effect of changes in cardiovascular disease (CVD) risk factors on progression from prehypertension (PreHTN) to hypertension (HTN) using an 8-yr prospective Korean Cancer Prevention Study (KCPS) by the National Health Insurance Corporation (NHIC) in Korea.</p></sec><sec><title>METHODS</title><p>A total of 16,229 subjects, aged 30 to 54, with new onset preHTN at baseline (1994-1996) in a biennial national medical exam were selected and followed up till 2004 at 2-yr intervals. All subjects underwent a biennial health examination including biochemical measurements and behavior. The log-rank test was performed to assess the relationship between changes in CVD risk factors and progression to HTN. The Cox proportional hazard model was used to identify factors influencing progression to HTN.</p></sec><sec><title>RESULTS</title><p>With regards the progression rate in men, ex-smokers (42.9%), abstainers (37.5%), and regular exercisers (37.6%) showed a slower progression rate than continuous smokers (49.5%) and continuous drinkers (50.9%). In women, those who participated in regular exercise (22.6%) had a lower rate of progression than continuous non-exercisers (36.1%). According to the results of the Cox proportional hazard model, improvements in smoking (hazard ratio [HR], 0.756), drinking (HR, 0.669), regular exercise (HR, 0.653), body mass index (HR, 0.715), and total cholesterol (HR, 0.788) played a protective role in progression to HTN in men, while in women, participating in regular exercise (HR, 0.534) was beneficial.</p></sec><sec><title>CONCLUSION</title><p>Improvements in CVD-related behaviors diminished the progression rate of HTN. This study suggests that individuals with PreHTN should be targeted for specific health behavioral intervention to prevent the progression of HTN.</p></sec>


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Socioeconomic Differentials in Mortality: A Cohort Study in 759,665 Korean men.
Yun Mi Song
Korean J Epidemiol. 1998;20(2):219-225.
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AbstractAbstract PDF
The relationship between Socioeconomic status(SES) and mortality, commonly studied in the developed countries but not in the less developed countries, was evaluated in a cohort of 759,665 Korean male public servants aged 30-64.
Data on the biological and social characteristics, SES defined as the grade of monthly salary were obtained from the Korea Medical Insurance Corporation. Vital status of the study subjects was followed-up from 1992 to 1996 through the dataset of the Korea National Statistical Office. The risk of ortality associated with SES was estimated using Cow proportional hazard model.
There were total 13,330 deaths during the five-year follow-up period. Lowest-SES group had significantly increased risk of all-cause mortality compared to the highest-SES group(Relative risk [RR]: 1.52). Mortality from cancer(RR=1.19) and cerebrovascular disease(RR=1.58) were also significantly increased in the lowest SES group. Mortality from ischemic heart desease, however, had no relationship with SES.
Socioeconomic differentials in mortality were reconfirmed in Korean men. The differences in the relationship between mortality and SES according to the specific cause of death suggest that SES influence health through the various pathways.

Epidemiol Health : Epidemiology and Health