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3 "Hyun-Joo Kong"
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Data Profile
Data profile: cancer sample cohorts (stomach, breast, colorectal, and liver) in Korea
Daewoo Pak, Suk Yong Jang, Jin-Ha Yoon, Dong Wook Kim, Jin-Won Noh, Dong-Woo Choi, Minyeong Guk, Hyeri Kim, Ju-Won Oh, Heejung Chae, Hyun-Joo Kong, Gi Hyun Kim, Ji Woong Nam, Ga Ram Lee, Dayun Park, Jehoo Jeon, Byungyoon Yun, Ki-Bong Yoo, Kui Son Choi
Epidemiol Health. 2025;47:e2025058.   Published online October 14, 2025
DOI: https://doi.org/10.4178/epih.e2025058
  • 5,143 View
  • 127 Download
AbstractAbstract AbstractSummary PDF
Abstract
Cancer Public Library Database (CPLD) links data from four major population-based public sources: the Korea National Cancer Incidence Database in the Korea Central Cancer Registry, cause-of-death data in Statistics Korea, the National Health Information Database in the National Health Insurance Service, and the National Health Insurance Research Database in the Health Insurance Review & Assessment Service. The National Cancer Data Center has developed a new nationally representative sample cohort dataset from Korean Clinical Data Utilization for Research Excellence project (K-CURE) CPLD: Stomach Cancer Sample Cohort, Breast Cancer Sample Cohort, Colorectal Cancer Sample Cohort, and Liver Cancer Sample Cohort. The sample populations consisted of approximately 21% of all cancer patients from 2012 to 2019. The populations of the Stomach Cancer Sample Cohort, Breast Cancer Sample Cohort, Colorectal Cancer Sample Cohort, and Liver Cancer Sample Cohort were 51,951, 39,586, 53,485, and 27,375 patients, respectively. The dataset included cancer incidence information, demographics, socioeconomic variables, health utilization data (procedures, diagnoses, and medications), general health checkup data, cancer screening data before and after the cancer incidence, as well as death information. These cohorts could help researchers analyze time-to-event data on mortality, treatment outcomes, comorbid conditions following a cancer diagnosis, and cancer incidence risk factors. The data can be accessed through the K-CURE portal (https://k-cure.mohw.go.kr/).
Summary
Korean summary
국립암센터의 국가암데이터센터는 K-CURE 사업의 일환으로 암·공공라이브러리를 구축하고 위암, 유방암, 대장암, 간암 표본을 공개하였다. 암·공공라이브러리는 국립암센터의 암등록자료를 기준으로 건강보험심사평가원 명세서, 국민건강보험공단 자격 및 검진자료, 통계청 사망자료를 결합하여 구축한 것으로 사용하기 쉽게 암종별 표본을 공개하고 있다. 암등록자료는 발생일자, 요약병기, ICD-O-3 코드를 포함해 기존 청구자료보다 정확한 암 예후 등의 연구가 원격으로 가능하다. 이용자는 희망시 맞춤형 자료로도 신청 가능하다. 사용 신청은 https://k-cure.mohw.go.kr/ 에서 가능하다.
Key Message
The National Cancer Data Center (NCDC) of the National Cancer Center(NCC) developed the Cancer Public Library Database (CPLD) under the Korean Clinical Data Utilization for Research Excellence project (K-CURE). CPLD is constructed by linking the NCC’s cancer registry data with claims data from the Health Insurance Review and Assessment Service, eligibility and health screening data from the National Health Insurance Service, and Cause-of-death data from Statistics Korea. The NCDC has opened sample cohorts for stomach, breast, colorectal, and liver cancers to promote cancer research with a remotely accessible environment. The data can be accessed through the K-CURE portal (https://k-cure.mohw.go.kr/).
Original Article
Regional disparities in major cancer incidence in Korea, 1999-2018
Eun Hye Park, Mee Joo Kang, Kyu-Won Jung, Eun Hye Park, E Hwa Yun, Hye-Jin Kim, Hyun-Joo Kong, Chang Kyun Choi, Jeong-Soo Im, Hong Gwan Seo, The Community of Population-Based Regional Cancer Registries
Epidemiol Health. 2023;45:e2023089.   Published online October 12, 2023
DOI: https://doi.org/10.4178/epih.e2023089
  • 20,626 View
  • 244 Download
  • 6 Web of Science
  • 5 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study investigated regional disparities in the incidence of 8 major cancers at the municipal level in Korea during 1999-2018 and evaluated the presence or absence of hot spots of cancer clusters during 2014-2018.
METHODS
The Korea National Cancer Incidence Database was used. Age-standardized incidence rates were calculated by gender and region at the municipal level for 4 periods of 5 years and 8 cancer types. Regional disparities were calculated as both absolute and relative measures. The possibility of clusters was examined using global Moran’s I with a spatial weight matrix based on adjacency or distance.
RESULTS
Regional disparities varied depending on cancer type and gender during the 20-year study period. For men, the regional disparities of stomach, colon and rectum, lung, and liver cancer declined, and those of thyroid and prostate cancer recently decreased, despite an overall increasing incidence. For women, regional disparities in stomach, colon and rectum, lung, liver, and cervical cancer declined, that of thyroid cancer recently decreased, despite an overall increasing incidence, and that of breast cancer steadily increased. In 2014-2018, breast cancer (I, 0.61; 95% confidence interval [CI], 0.53 to 0.70) showed a high probability of cancer clusters in women, and liver cancer (I, 0.48; 95% CI, 0.40 to 0.56) showed a high probability of cancer clusters in men.
CONCLUSIONS
Disparities in cancer incidence that were not seen at the national level were discovered at the municipal level. These results could provide important directions for planning and implementing local cancer policies.
Summary
Korean summary
이 연구는 한국 시군구 단위에서 지난 20년(1999-2018)간 주요 8개 암 발생률의 지역 간 격차를 조사하고, 최근 5년(2014-2018)의 암 발생 군집 가능성을 평가했습니다. 지역 간 격차는 여성에서 갑상선암, 남성에서는 폐암이 가장 큰 격차를 보였습니다. 군집 가능성은 여성의 경우 유방암, 남성의 경우 간암에서 가장 높았습니다. 전국 단위에서는 볼 수 없었던 지역 간 격차 및 군집 발생 가능성이 시군구 단위에서 발견되었고, 이러한 결과는 지역에 맞는 암 정책을 기획하고 실행하는 데 중요한 방향을 제시할 수 있을 것입니다.
Key Message
This study investigated regional disparities in the incidence of eight major cancers in Korea at the municipal level during 1999-2018 and assessed the possibility of cancer clusters during 2014-2018. Thyroid cancer in women and lung cancer in men showed the most significant regional disparities. Breast cancer in women and liver cancer in men displayed the highest possibility of clustering. Regional disparities and cancer clusters were identified locally, which were not detected nationally. These findings could provide valuable guidance for developing and implementing cancer policies that are tailored to local needs.

Citations

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Data Profile
National Epidemiologic Survey of Thyroid cancer (NEST) in Korea
Chang-Mo Oh, Hyun-Joo Kong, Eunyang Kim, Hyejin Kim, Kyu-Won Jung, Sohee Park, Young-Joo Won
Epidemiol Health. 2018;40:e2018052.   Published online October 26, 2018
DOI: https://doi.org/10.4178/epih.e2018052
  • 30,159 View
  • 284 Download
  • 33 Web of Science
  • 35 Crossref
AbstractAbstract PDF
Abstract
The Korea Central Cancer Registry conducted the National Epidemiologic Survey of Thyroid cancer (NEST) to investigate changes in the epidemiological and clinical characteristics of thyroid cancer patients between 1999 and 2008. The NEST was designed to collect representative samples of patients with thyroid cancer diagnosed in the years 1999, 2005, and 2008 using a proportionally stratified and systematic random sampling method. Among 42,891 participants diagnosed with thyroid cancer, 5,796 participants were included in the final study population. This survey collected information on diagnostic methods and date, route of diagnosis, prior medical history and history of thyroid-related disease, tumor, lymph node, metastasis and collaborative stage, and treatment. The NEST dataset was also linked to the cause-of-death database from Statistics Korea. The mean age of the study participants was 46.9 years. The ratio of men to women was 1:5.5. In the analysis of the histologic type of cancer, the proportion of papillary thyroid carcinoma showed an increasing trend (p<0.01). In contrast, the proportion of distant metastasis and the mean tumor size of thyroid cancers showed decreasing trends over time (p<0.01, respectively).
Summary

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