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Effects of antibiotic consumption on children 2-8 years of age developing asthma
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Hamid Reza Khalkhali, Sima Oshnouei, Shaker Salarilak, Mohammadhossein Rahimi Rad, Mohammad Karamyar, Javad Khashabi
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Epidemiol Health. 2014;36:e2014006. Published online July 4, 2014
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DOI: https://doi.org/10.4178/epih/e2014006
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Abstract
OBJECTIVES
Antibiotic exposure in children is a possible contributor to the increasing asthma prevalence in several countries. The present study aimed to investigate the association between antibiotic exposure and the risk of developing childhood asthma at 2-8 years of age.
METHODS A case-control study was undertaken among children aged 2-8 years old between March and September 2010 in the Urmia district in the northwest of Iran. The cases were doctor-diagnosed asthmatic children based on Global Initiative for Asthma criteria (n=207), and the controls were children without respiratory symptoms (n=400) selected by frequency matching by age and gender. Clinical data including antibiotic exposure was collected by a validated and reliable questionnaire, which was completed by interviewing parents/guardians.
RESULTS Antibiotic consumption during the first year of life increased the odds ratio [OR] of asthma symptoms at 2-8 years of age (crude OR, 2.26; 95% confidence interval [CI], 1.53-3.35; p<0.01), and the strength of association was similar after adjusting for a family history of asthma or atopic disorder, preterm delivery, birth order, and delivery method (adjusted OR, 1.91; 95% CI, 1.27-2.88; p=0.03).
CONCLUSIONS Our study suggests that antibiotic consumption in children was associated with an increased risk of childhood asthma, and an additional confirmative study is needed.
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Summary
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Citations
Citations to this article as recorded by  - Progress in Etiology of Persistent Wheezing in Infants
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Chest.2020; 157(2): 334. CrossRef - The relationship of prenatal antibiotic exposure and infant antibiotic administration with childhood allergies: a systematic review
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BMC Pediatrics.2020;[Epub] CrossRef - Respiratory morbidity, atopy and asthma at school age in preterm infants aged 32–35 weeks
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European Journal of Pediatrics.2019; 178(7): 973. CrossRef - Evaluation of Allergic Symptoms Prevalence and Its Relationship with Acetaminophen/Antibiotic Use and Hospitalization Among School-Aged Children in Tehran, Iran
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Iranian Red Crescent Medical Journal.2017;[Epub] CrossRef - Airway Microbiota and the Implications of Dysbiosis in Asthma
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Current Allergy and Asthma Reports.2016;[Epub] CrossRef - Early-life antibiotic use is associated with wheezing among children with high atopic risk: a prospective European study
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Journal of Asthma.2015; 52(7): 647. CrossRef
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