Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Browse articles > Author index
Search
Kyu-Won Jung 3 Articles
Effect of Pap smears on the long-term survival of cervical cancer patients: a nationwide population-based cohort study in Korea
Xuan Quy Luu, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, kyu-won Jung, Myong Cheol Lim, Kui Son Choi
Epidemiol Health. 2022;44:e2022072.   Published online September 7, 2022
DOI: https://doi.org/10.4178/epih.e2022072
  • 854 View
  • 64 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to investigate the effect of cervical cancer screening by Papanicolaou (Pap) smears on the long-term survival of cervical cancer patients.
METHODS
We constructed a retrospective cohort of 14,903 women diagnosed with invasive cancer or carcinoma in situ in 2008 and 2009 and followed up until December 31, 2019, by using individual-level data from 3 national databases of the Korean National Cancer Screening Program, the Korean Central Cancer Registry, and death certificates. Cox proportional-hazards regression was used to investigate the effect of cervical cancer screening on mortality.
RESULTS
In total, 12,987 out of 14,867 patients (87.4%) were alive at the end of the follow-up period (median: 10.5 years). Screened patients had a 38% lower risk of cervical cancer death than never-screened patients (hazard ratio [HR], 0.62; 95% confidence interval [CI], 0.54 to 0.70). Screening was associated with 59% and 35% lower risks of death, respectively, in screened patients with localized and regional stages. Furthermore, lower HRs among women who received screening were observed in all age groups, especially women aged 50–59 years (HR, 0.54; 95% CI, 0.42 to 0.69). The lowest HR for cervical cancer death was reported among patients screened within the past 2 years (HR, 0.54; 95% CI, 0.47 to 0.63), and the HRs increased with increasing time intervals.
CONCLUSIONS
Pap smear screening significantly reduced the risk of cervical cancer-specific death in Korean women across all cancer stages.
Summary
Korean summary
한국은 자궁경부암 발생과 사망을 낮추기 위하여 국가암검진사업으로 자궁경부암 검진을 실시하고 있다. 이 연구는 2008-2009년 자궁경부암 진단을 받은 30세-79세 14,903명을 대상으로 과거 자궁경부세포검진 여부에 따른 장기생존율을 추적 조사하였다. 그 결과 자궁경부암 검진을 받은 환자에서 사망 위험비가 약 38% 낮았으며, 2년 이내에 검진을 받은 환자군에서 사망 위험이 가장 낮았다.
Key Message
The Korean National Cancer Screening Program (KNCSP) has provided cervical cancer screening by Pap smear test. However, the survival, particularly long-term survival of cervical cancer patients, has never been evaluated in the KNCSP. This study reports a significant improvement in the long-term survival of screened cervical cancer patients, which persist in subgroup analysis by cancer stage. Patients who were screened within two years before the diagnosis had the best survival.
Effect of mammography screening on the long-term survival of breast cancer patients: results from the National Cancer Screening Program in Korea
Xuan Quy Luu, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, Kyu-Won Jung, Kui Son Choi
Epidemiol Health. 2022;44:e2022094.   Published online October 26, 2022
DOI: https://doi.org/10.4178/epih.e2022094
  • 602 View
  • 47 Download
AbstractAbstract PDF
Abstract
OBJECTIVES
This study investigated the effect of mammography screening on the long-term survival of breast cancer (BC) patients aged 40 years or older according to their screening history and duration since screening.
METHODS
The study cohort was organized from 3 nationwide databases of the Korean National Cancer Screening Program, the Korean Central Cancer Registry, and death certificates. We included 24,387 women diagnosed with invasive BC or ductal carcinoma in situ in 2008 and 2009 and followed up until December 31, 2019. Cox proportional-hazards regression was used to investigate the effect of BC screening on the risk of death.
RESULTS
Overall, 20,916 of 24,387 patients (85.8%) were alive at the end of the follow-up period (median: 10.5 years). The long-term survival rate was significantly lower in the never-screened group (80.3%) than in the screened group (88.9%) (p<0.001). A 35% reduction in the risk of BC death (hazard ratio [HR], 0.65; 95% confidence interval [CI], 0.60 to 0.70) from screening was observed. A subgroup analysis according to the cancer stage showed 62%, 36%, and 24% lower risks of BC death for the localized stage, regional stage, and distant stage, respectively. Women aged 40-49 years received the least benefit from BC screening (HR, 0.71; 95% CI, 0.62 to 0.81).
CONCLUSIONS
Mammography screening was effective in reducing the risk of BC-specific death in Asian women across all cancer stages. However, this effect was relatively small among women in their 40s, suggesting that more detailed and specialized screening strategies are needed for that age group.
Summary
Korean summary
Key Message
National Epidemiologic Survey of Thyroid cancer (NEST) in Korea
Chang-Mo Oh, Hyun-Joo Kong, Eunyang Kim, Hyejin Kim, Kyu-Won Jung, Sohee Park, Young-Joo Won
Epidemiol Health. 2018;40:e2018052.   Published online October 26, 2018
DOI: https://doi.org/10.4178/epih.e2018052
  • 9,021 View
  • 244 Download
  • 18 Citations
AbstractAbstract PDF
Abstract
The Korea Central Cancer Registry conducted the National Epidemiologic Survey of Thyroid cancer (NEST) to investigate changes in the epidemiological and clinical characteristics of thyroid cancer patients between 1999 and 2008. The NEST was designed to collect representative samples of patients with thyroid cancer diagnosed in the years 1999, 2005, and 2008 using a proportionally stratified and systematic random sampling method. Among 42,891 participants diagnosed with thyroid cancer, 5,796 participants were included in the final study population. This survey collected information on diagnostic methods and date, route of diagnosis, prior medical history and history of thyroid-related disease, tumor, lymph node, metastasis and collaborative stage, and treatment. The NEST dataset was also linked to the cause-of-death database from Statistics Korea. The mean age of the study participants was 46.9 years. The ratio of men to women was 1:5.5. In the analysis of the histologic type of cancer, the proportion of papillary thyroid carcinoma showed an increasing trend (p<0.01). In contrast, the proportion of distant metastasis and the mean tumor size of thyroid cancers showed decreasing trends over time (p<0.01, respectively).
Summary
Korean summary
Key Message

Citations

Citations to this article as recorded by  
  • Quantification and Pattern of Central Compartment Lymph Nodes in pN1a Papillary Thyroid Cancer Patients
    Chang Liu, Hui Liu, Cong Bian, Xi-Yu Yao, Yu Wu, Shun-Jin Chen
    Ear, Nose & Throat Journal.2022; : 014556132211044.     CrossRef
  • Dyslipidemia Risk in Thyroid Cancer Patients: A Nationwide Population-Based Cohort Study
    Youhyun Song, Hye Sun Lee, Goeun Park, Sang-Wook Kang, Ji Won Lee
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Incidence of thyroid cancer in Abu Dhabi, UAE: A registry-based study
    Eiman Alseddeeqi, Ajda Altinoz, Abderrahim Oulhaj, Abubaker Suliman, LuaiA Ahmed
    Journal of Cancer Research and Therapeutics.2022;[Epub]     CrossRef
  • Clinical Significance of Tumor Size in Gross Extrathyroidal Extension to Strap Muscles (T3b) in Papillary Thyroid Carcinoma: Comparison with T2
    Joonseon Park, Il Ku Kang, Ja Seong Bae, Jeong Soo Kim, Kwangsoon Kim
    Cancers.2022; 14(19): 4615.     CrossRef
  • TERT Promoter Mutations and the 8th Edition TNM Classification in Predicting the Survival of Thyroid Cancer Patients
    Jun Park, Sungjoo Lee, Kyunga Kim, Hyunju Park, Chang-Seok Ki, Young Lyun Oh, Jung Hee Shin, Jee Soo Kim, Sun Wook Kim, Jae Hoon Chung, Tae Hyuk Kim
    Cancers.2021; 13(4): 648.     CrossRef
  • Adequacy and Effectiveness of Watson For Oncology in the Treatment of Thyroid Carcinoma
    Hyeok Jun Yun, Hee Jun Kim, Soo Young Kim, Yong Sang Lee, Chi Young Lim, Hang-Seok Chang, Cheong Soo Park
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • Clinicopathological features of Differentiated Thyroid Cancer presenting in the UK versus internationally: An observational cohort study
    R. Sawant, S.Y. Hey, K. Hulse, A. Hay, F.W. Gibb, R. Adamson, I.J. Nixon
    Clinical Otolaryngology.2021; 46(3): 522.     CrossRef
  • Analyses of the Association between Thyroid Cancer and Osteoporosis/Fracture Histories: A Cross-Sectional Study Using KoGES HEXA Data
    Young-Ju Jin, Chang-Myeon Song, Bum-Jung Park, Hyo-Geun Choi
    International Journal of Environmental Research and Public Health.2021; 18(9): 4732.     CrossRef
  • Clinicopathological Features of Patients Diagnosed with Both Primary Thyroid Cancer and Primary Renal Cell Cancer and Its Comparison with Patients with Thyroid Cancer or Renal Cell Cancer Alone
    Jun Park, Young Nam Kim, Hyunsoo Ryoo, Hyunju Park, So Young Park, Tae Hyuk Kim, Jae Hoon Chung, Seong Il Seo, Sun Wook Kim
    International Journal of Thyroidology.2021; 14(1): 28.     CrossRef
  • Proposal of a New Prognostic Model for Differentiated Thyroid Cancer with TERT Promoter Mutations
    Jun Park, Sungjoo Lee, Jiyun Park, Hyunju Park, Chang-Seok Ki, Young-Lyun Oh, Jung-Hee Shin, Jee-Soo Kim, Sun-Wook Kim, Jae-Hoon Chung, Kyunga Kim, Tae-Hyuk Kim
    Cancers.2021; 13(12): 2943.     CrossRef
  • Thyroid cancer awareness among women in the asir region of Saudi Arabia
    MajedSaad Al Fayi
    King Khalid University Journal of Health Sciences.2021; 6(1): 27.     CrossRef
  • Spatial distribution and determinants of thyroid cancer incidence from 1999 to 2013 in Korea
    Jieun Jang, Dae-Sung Yoo, Byung Chul Chun
    Scientific Reports.2021;[Epub]     CrossRef
  • Association of Screening by Thyroid Ultrasonography with Mortality in Thyroid Cancer: A Case–Control Study Using Data from Two National Surveys
    Jae Kwan Jun, Soon-Young Hwang, Seri Hong, Mina Suh, Kui Son Choi, Kyu-Won Jung
    Thyroid.2020; 30(3): 396.     CrossRef
  • Thyroid cancer among patients with thyroid nodules in Yemen: a three-year retrospective study in a tertiary center and a specialty clinic
    Butheinah A. Al-Sharafi, Jamila A. AlSanabani, Ibraheem M. Alboany, Amani M. Shamsher
    Thyroid Research.2020;[Epub]     CrossRef
  • Emerging Roles of Long Noncoding RNA Regulator of Reprogramming in Cancer Treatment


    Di-Er Sun, Shu-Yuan Ye
    Cancer Management and Research.2020; Volume 12: 6103.     CrossRef
  • Unusual metastases from differentiated thyroid cancers: A multicenter study in Korea
    Jee Hee Yoon, Min Ji Jeon, Mijin Kim, A. Ram Hong, Hee Kyung Kim, Dong Yeob Shin, Bo Hyun Kim, Won Bae Kim, Young Kee Shong, Ho-Cheol Kang, Domenico Albano
    PLOS ONE.2020; 15(8): e0238207.     CrossRef
  • Association between Family Histories of Thyroid Cancer and Thyroid Cancer Incidence: A Cross-Sectional Study Using the Korean Genome and Epidemiology Study Data
    Soo-Hwan Byun, Chanyang Min, Hyo-Geun Choi, Seok-Jin Hong
    Genes.2020; 11(9): 1039.     CrossRef
  • Circular RNAs Regulate Cancer Onset and Progression via Wnt/β-Catenin Signaling Pathway
    Yun-Feng Li, Jian Zhang, Lei Yu
    Yonsei Medical Journal.2019; 60(12): 1117.     CrossRef

Epidemiol Health : Epidemiology and Health