Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Browse articles > Author index
Search
Khoshideh Babak 1 Article
Clinical and laboratory findings of rhabdomyolysis in opioid overdose patients in the intensive care unit of a poisoning center in 2014 in Iran
Khoshideh Babak, Arefi Mohammad, Ghorbani Mazaher, Akbarpour Samaneh, Taghizadeh Fatemeh
Epidemiol Health. 2017;39:e2017050.   Published online November 8, 2017
DOI: https://doi.org/10.4178/epih.e2017050
  • 16,370 View
  • 261 Download
  • 14 Web of Science
  • 13 Crossref
AbstractAbstract PDF
Abstract
OBJECTIVES
The aim of this study was to investigate the clinical and demographic characteristics and some laboratory findings of hospitalized patients with acute opioid toxicity and rhabdomyolysis.
METHODS
This cross-sectional study investigated 354 patients hospitalized at Baharloo Hospital in Tehran in 2014 with acute illicit drug toxicity. Data were collected using an investigator-made checklist. The collected data (such as mortality rate, demographic data, and renal function tests, as well as serum biochemical findings) were analyzed by descriptive statistics and the chi-square test.
RESULTS
A total of 354 patients were admitted to the hospital in 2014 with acute illicit drug toxicity, including 291 males and 63 females. The total number of patients with rhabdomyolysis was 76 (21.5% of the total), of whom 69 (90.8%) were male and 7 (9.2%) were female. Most cases of rhabdomyolysis were associated with methadone abuse, followed by opium abuse. Rhabdomyolysis was most common in those 20-29 and 30-39 years old, with methadone and opium the most commonly abused illicit drugs. The mean blood urea level was 3.8±1.0 mg/dL, and the mean serum potassium and sodium levels were 3.8±0.3 mg/dL and 140.4±4.0 mg/dL, respectively. Five patients, all of whom were male, passed away due to severe renal failure (6.5%).
CONCLUSIONS
Toxicity caused by opioids is associated with clinical complications and laboratory disorders, such as electrolyte disorders, which can lead to lethal or life-threatening results in some cases. Abnormal laboratory test findings should be identified in patients with opioid toxicity in order to initiate efficient treatment.
Summary

Citations

Citations to this article as recorded by  
  • Opioids and the kidney: two sides of the same coin
    Shaowei Gao, Qiulan He
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Poppy intoxication in children: The interest of early administration of naloxone
    Hasnae Hoummani, Said Benlamkaddem, Sanae Achour
    Toxicologie Analytique et Clinique.2024;[Epub]     CrossRef
  • Mental health status, health service utilization, drug use behaviors associated with non-fatal overdose among people who use illicit drugs: A meta-analysis
    Bahram Armoon, Peter Higgs, Rasool Mohammadi
    Journal of Substance Use.2023; 28(2): 154.     CrossRef
  • Incidence of rhabdomyolysis occurrence in psychoactive substances intoxication: a systematic review and meta-analysis
    Alireza Amanollahi, Tannaz Babeveynezhad, Mohsen Sedighi, Shahin Shadnia, Sadaf Akbari, Mahbobeh Taheri, Mahboobeh Besharatpour, Goljamal Jorjani, Elham Salehian, Koorosh Etemad, Yadollah Mehrabi
    Scientific Reports.2023;[Epub]     CrossRef
  • Public health risks associated with methadone in Iran: A systematic review and meta-analysis
    Yasna Rostam-Abadi, Jaleh Gholami, Alireza Noroozi, Mina Ansari, Shahab Baheshmat, Marziyeh Hamzehzadeh, Mohammad Reza Ghadirzadeh, Bita Vahdani, Hamed Ekhtiari, Ramin Mojtabai, Afarin Rahimi-Movaghar
    International Journal of Drug Policy.2022; 100: 103529.     CrossRef
  • A Fatal Case of Opioid Intoxication After Raw Poppy Plant Ingestion
    Gurkan Bozan, Hasan Bora Ulukapi, Ummuhan Oncul, Serkan Levent, Ener C Dinleyici
    Cureus.2021;[Epub]     CrossRef
  • Opioids and Acute Kidney Injury
    Mary Mallappallil, Siddhartha Bajracharya, Moro Salifu, Ernie Yap
    Seminars in Nephrology.2021; 41(1): 11.     CrossRef
  • Epidemiology and the Impact of Acute Kidney Injury on Outcomes in Patients with Rhabdomyolysis
    Chien-Wen Yang, Si Li, Yishan Dong, Nitpriya Paliwal, Yichen Wang
    Journal of Clinical Medicine.2021; 10(9): 1950.     CrossRef
  • Review of Neurologic Comorbidities in Hospitalized Patients With Opioid Abuse
    Kevin R. Nelson, Katelyn Dolbec, William Watson, Hanwen Yuan, Mam Ibraheem
    Neurology Clinical Practice.2021; 11(6): 527.     CrossRef
  • Multiple limb compartment syndrome as a manifestation of capillary leak syndrome secondary to metformin and dipeptidyl peptidase IV inhibitor overdose
    Daisuke Kasugai, Kosuke Tajima, Naruhiro Jingushi, Norimichi Uenishi, Akihiko Hirakawa
    Medicine.2020; 99(29): e21202.     CrossRef
  • Case report: Methadone caused rhabdomyolysis
    Zoran Kovačević, Maja Derić-Jeremić, Danijela Derić, Neda Ognjanović, Maja Sazdanović
    Engrami.2020; 42(1): 83.     CrossRef
  • Non -fatal overdose among people who inject drugs in Tehran, Iran
    Mehdi Noroozi, Peter Higgs, Azadeh Bayani, Bahram Armoon, Ali Nazeri Astaneh, Ladan Fattah Moghaddam, Mohammad Askari
    Substance Abuse Treatment, Prevention, and Policy.2020;[Epub]     CrossRef
  • Methadone overdose

    Reactions Weekly.2017; 1679(1): 111.     CrossRef

Epidemiol Health : Epidemiology and Health
TOP