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Jong Won Kang 2 Articles
Current Status of Multicenter Cancer Cohort Study with Biological Materials Bank in Korea.
Keun Young Yoo, Hai Rim Shin, Song Hun Chang, Jung Myung Choi, Chang Yup Kim, Kun Sei Lee, Won Jin Lee, Dae Hee Kang, Bu Ok Lee, Duck Hee Lee, Sue Kyung Park, Joo Hon Sung, Yeong Su Ju, Dae Sung Kim, Jong Won Kang, Soo Hun Cho
Korean J Epidemiol. 1998;20(2):275-278.
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Abstract
This cohort study is a collaborative effort of 8 institutions. The goal is to establish a large scale cohort that can be followed for 10 or more years to assess the relationship between life-styles and cancer occurrence, and to evaluate the role of environmental exposures in the development of six major sites of cancers(stomach, liver, lung, colorectum, uterine cervix and female breast) in the rural population. Since 1993, 11,304 men and women aged over 35 living in four areas have been recruited. The number of target population is 30,000 persons, which is expected to be successfully recruited until 1999. Each subject has completed a detailed questionnaire on general life-styles, reproductive factors, and agricultural chemical exposures through the interview. Anthropometric measurements with body fat composition and the routine clinical laboratories were examined. For the cancer-free cohort, physical examination by the physicians and serologic tests for hepatitis markers, some tumor markers, and lipid profile have been done, but not all. In order to provide an opportunity to incorporate barious biomarkers of exposure and effect as well as genetic susceptibility, a biologic tissue bank has been established from blood and urine sample(plasma, WBC buffy-coat, RBC clots, and urine supernatant) stored at-70degrees C. Re-examination of changes in exposere to risk factors will be done periodically. Disease occurrence will be ascertained by the active(mainly through diagnosis by physicians) and the passive surveillance(through both death certificate and screening of medical utilization records).
Summary
An epidemiologic survey on cancer epidemic at pukcheju-gun.
Yoon Ok Ahn, Byung Joo Park, Jong Myon Bae, Duk Hyung Lee, Dong Jin Kim, Jun Hwan Kim, Jong Won Kang, Yong Jin Jung, Dong Mo Rhie
Korean J Epidemiol. ;15(2):185-195.
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Abstract
According to a newspaper account for the epidemic occurrence of cancer patients at an area of Pukcheju-gun, epidemic survey was conducted to identify the epidemicity and possible cause of the cancer epidemic from Sep. 23, 1993 to Sep. 28, 1993. Housefold survey for identifying prevalent There was no female cancer cases, no temporal dusting pattern of cancer occurrence and no clustering of specific types of cancer. In the evaluation of ground water and sea water, carcinogenic substances were not detected. According to the above evidences, it was difficult to confirm that there was an epidemic occurrence of cancer at the area. And the possibility of the association of environmental carcinogenic factors with the cancer occurrence seemed to be very low.
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