Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Browse articles > Author index
Search
Babak Mirbagheri 1 Article
Temporal trend and spatial distribution of acute lymphoblastic leukemia in Iranian children during 2006-2014: a mixed ecological study
Sajjad Rahimi Pordanjani, Amir Kavousi, Babak Mirbagheri, Abbas Shahsavani, Koorosh Etemad
Epidemiol Health. 2020;42:e2020057.   Published online July 29, 2020
DOI: https://doi.org/10.4178/epih.e2020057
  • 6,542 View
  • 173 Download
  • 3 Citations
AbstractAbstract PDF
Abstract
OBJECTIVES
The present study investigated the spatiotemporal epidemiological status of acute lymphoblastic leukemia (ALL), the most common childhood cancer, in Iran.
METHODS
Using an exploratory mixed design, this ecological study examined 3,769 under-15 children with ALL recorded in the National Cancer Registry of Iran during 2006-2014. Data were analyzed using the Mann-Whitney U test, the Getis-Ord general G (GOGG) index, optimized hot spot analysis, and Pearson correlation coefficients (PCC) at a significance level of 0.05.
RESULTS
The average annual incidence of the disease was 2.25 per 100,000 under-15 children, and the cumulative incidence rate (CIR) was 21.31 per 100,000 under-15 children. Patients’ mean age was 5.90 years (standard deviation, 3.68), and the peak incidence was observed among 2-year to 5-year-olds. No significant difference was found in mean age between boys and girls (p=0.261). The incidence of ALL was more common during spring and summer than in other seasons. The GOGG index was 0.039 and significant (p<0.001). Hot spots were identified in south, central, and eastern Iran and cold spots in the north and west of Iran. The PCC between the CIR and latitude was negative (r=-0.507; p=0.003) but that between the CIR and longitude was positive (r=0.347; p=0.055).
CONCLUSIONS
The incidence of ALL in Iranian children was lower than that observed in developed countries, but showed an increasing trend. It can be argued that the incidence of ALL is due to synergistic interactions between environmental, infectious, geographical, and genetic risk factors.
Summary
Korean summary
Key Message

Citations

Citations to this article as recorded by  
  • Persistently high incidence rates of childhood acute leukemias from 2010 to 2017 in Mexico City: A population study from the MIGICCL
    Janet Flores-Lujano, David Aldebarán Duarte-Rodríguez, Elva Jiménez-Hernández, Jorge Alfonso Martín-Trejo, Aldo Allende-López, José Gabriel Peñaloza-González, María Luisa Pérez-Saldivar, Aurora Medina-Sanson, José Refugio Torres-Nava, Karina Anastacia Sol
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Epidemiological characteristics and temporal-spatial analysis of overseas imported dengue fever cases in outbreak provinces of China, 2005–2019
    Xinchang Lun, Yiguan Wang, Chunchun Zhao, Haixia Wu, Caiying Zhu, Delong Ma, Mingfang Xu, Jun Wang, Qiyong Liu, Lei Xu, Fengxia Meng
    Infectious Diseases of Poverty.2022;[Epub]     CrossRef
  • Temporal Trend and Spatial Distribution of Drug Poisoning in Semnan Province: A Retrospective Longitudinal Study
    Masoudeh Babakhanian, Khadijeh Mamashli, Faezeh Ansariniya, Somayeh Rezaie, Hamed Azadi, Masumeh Ghazanfarpour, Sajjad Rahimi Pordanjani
    Middle East Journal of Rehabilitation and Health Studies.2022;[Epub]     CrossRef

Epidemiol Health : Epidemiology and Health