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To investigate the 10 major causes of death in Korea in 1980 by sex, age grouped and residential area among all death recorded on death registration form in Economic Planning Board, the 58,187 deaths diagnosed by doctors were classified in accordance with the Korean Standard Classifications of Diseases, Mortality List of 50 Causes. The results are as follows: 1) The 10 major causes of death in Korea were cerebrovascular disease, hypertensive disease, poisoning and toxic effects, malignant neoplasm of stomach, chronic liver disease and cirrhosis, tuberculosis, motor vehicle traffic accident, suicide, bronchitis emphysema and asthma, and pneumonia in that order. 2) The 10 major causes of death of male in Korea were cerebrovascular disease, hypertensive disease, poisoning and toxic effects, chronic liver disease and cirrhosis, malignant neoplasm of stomach, tuberculosis, motor vehicle traffic accident, suicide, bronchitis emphysema and asthma, and pneumonia in that order. 3) The 10 major causes of death of female in Korea were cerebrovascular disease, hypertensive disease, poisoning and toxic effects, malignant neoplasm of stomach, tuberculosis, suicide, chronic liver disease and cirrohosis, bronchitis emphysema and asthma, motor vehicle accident, and pneumonia in that order. 4) The 10 major causes of death of 0~14 age group in Korea were motor vehicle traffic accident, pneumonia, congenital anomalies, poisoning and toxic effects, meningitis, cerebrovascular disease, burns, tuberculosis, leukaemia, and bronchitis emphysema and asthma in that order. 5) The 10 major causes of 15~44 age group in Korea were poisoning and toxic effects, suicide, motor vehicle traffic accident, cerebrovascular disease, tuberculosis, chronic liver disease and cirrhosis, hypertensive disease, malignant neoplasm of stomach, nephritis nephrotic syndrome and nephrosis, and pneumonia in that order. 6) The 10 major causes of death of 45~64 age group in Korea were hypertensive disease, cerebrovascular disease, chronic liver disease and cirrhosis, malignant neoplasm of stomach, tuberculosis, poisoning and toxic effects, suicide, motor vehicle traffic accident, malignant neoplasm of trachea bronchus and lung, and diabetes mellitus in that order. 7) The 10 major causes of death of 65 and over age group in Korea were cerebrovascular disease, hypertensive disease, malignant neoplasm of stomach, bronchitis emphysema and asthma, chronic liver disease tand cirrhosis, uberculosis, pneumonia, poisoning and toxic effects, malignant neoplasm of trachea bronchus and lung, and diabetes mellitus in that order. 8) The 10 major causes of death in urban area were cerebrovascular disease, hypertensive disease, poisoning and toxic effects, malignant neoplasm of stomach, chronic liver disease and cirrhosis, tuberculosis, motor vehicle traffic accident, suicide, bronchitis emphysema and asthma, and pneumonia in that order. 9) The 10 major causes of death in rural area were cerebrovascular disease, poisoning and toxic effects, hypertensive disease, suicide, chronic liver disease and cirrhosis, malignant neoplasm of stomach, motor vehicle traffic accident, tuberculosis, bronchitis emphysema and asthma, and pneumonia in that order.