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Korean Journal of Epidemiology 1984;6(1): 16-26.
한국에서 유행한 Leptospirosis의 세균학적 연구
조민기, 백승복, 오희복, 송철
Bacteriological studies on Leptospirosis in Korea (1984)
Min Kee Cho, Sung Bok Paik, Hee Bok Oh, Chul Song
A bacteriological investigation was conducted on haemorrhagic mimicking pneumonia, which was prevalent in rural areas in Wonju, Gangwon-do and Gwangju, Jeonnam between August and Octo-ber 1984. The following results were found. 1. Leptospira interrogans was separated and identified from two patients. 2. Leptospira interrogans was separated and identified from seven out of 45 field mice collect-ed from the area that had the case of leptospira interrogans in Wonju and Gwangju. 3. The nine separated strains were all found to have pathogenicity from the guinea pig. 4. Two strains separated from the humans and five strains from the field mice all belonged to the same serotype group and were identified as leptospira interrogans serogroup ictero-haemorrgagiae. 5. The separated strains were confirmed to have the typical leptospira interrogans form and mobility. An observation through electron microscope revealed the following: width 0.1–0.15 µm, length 6–15 µm, wave length of the coil 0.2–0.5 µm, number of pitches of coil 18–23, two periplasmic flagella, and a clockwise twist direction of the coil. 6. A total of 32 (91%) out of 35 hospitalized patients in Wonju and Gwangju possessed anti-bodies to leptospira interrogans (isolates) and the seroprevalence of the healthy control group such as the patients’ family members and people living in the same environment was just 2% (1 out of 51 people).


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