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Special edition Bacteriological studies on Leptospirosis in Korea (1984)
Min Kee Cho, Sung Bok Paik, Hee Bok Oh, Chul Song
Epidemiol Health 1984;6(1):16-26
DOI: https://doi.org/
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A bacteriological investigation was conducted on haemorrhagic mimicking pneumonia, which was prevalent in rural areas in Wonju, Gangwon-do and Gwangju, Jeonnam between August and Octo-ber 1984. The following results were found. 1. Leptospira interrogans was separated and identified from two patients. 2. Leptospira interrogans was separated and identified from seven out of 45 field mice collect-ed from the area that had the case of leptospira interrogans in Wonju and Gwangju. 3. The nine separated strains were all found to have pathogenicity from the guinea pig. 4. Two strains separated from the humans and five strains from the field mice all belonged to the same serotype group and were identified as leptospira interrogans serogroup ictero-haemorrgagiae. 5. The separated strains were confirmed to have the typical leptospira interrogans form and mobility. An observation through electron microscope revealed the following: width 0.1–0.15 µm, length 6–15 µm, wave length of the coil 0.2–0.5 µm, number of pitches of coil 18–23, two periplasmic flagella, and a clockwise twist direction of the coil. 6. A total of 32 (91%) out of 35 hospitalized patients in Wonju and Gwangju possessed anti-bodies to leptospira interrogans (isolates) and the seroprevalence of the healthy control group such as the patients’ family members and people living in the same environment was just 2% (1 out of 51 people).

Epidemiol Health : Epidemiology and Health