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The annual risk of tuberculous infection (hereinafter the risk of infection) has some advantages over the other indices used in tuberculosis epidemiology. The authors estimated the risk of infection in Korea from the infection rates of 5-9 years old children examined during the National Tuberculosis Prevalence Surveys which were carried out at 5 year intervals since 1965. The method developed by the Tuberculosis Surveillance Research Unit was used in estimating the risk of infection. 1. Overall risk of infection was 4.16% in 1965 and 1.31% in 1980, decreasing at an annual rate of 7.7%. The risk of infection will be 0.97% in 1984 if the same decreasing trend continues. 2. There was little difference in the risks of infection and their annual reduction rates between the male and the female. 3. The risk of infection among the urban population was 5.19% in 1965 and 1.21% in 1980, decreasing at an annual rate of 9.7%. On the other hand, the risk of infection among the rural population was 3.75% in 1965 and 1.39% in 1980 with the annual reduction rate of 6.6%. The difference in the annual reduction rates between the urban and rural areas was statistically significant (p<0.005). 4. Further exploration is required to establish the cause(s) for the slower decrease in the risk of infection among the rural population.