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Original Article Association between smoking and the risk of dental implant failure in Korean adults: a nationwide cohort study
Yu-Rin Kim1*orcid , Minkook Son2*orcid , hyeon Ji Kim3orcid , Seon-Rye Kim4orcid
Epidemiol Health 2026;48e2026002-0
DOI: https://doi.org/10.4178/epih.e2026002
Published online: January 14, 2026
1Department of Dental Hygiene, Silla University, Busan, Korea
2Department of Physiology, Dong-A University College of Medicine, Busan, Korea
3Department of Data Sciences Convergence, Dong-A University, Busan, Korea
4Research Institute of Health Medical Education Convergence, Kangwon National University, Samcheok, Korea
Corresponding author:  hyeon Ji Kim,
Email: hyeonji.kim.e@gmail.com
Seon-Rye Kim,
Email: sjsanj@hanmail.net
* Yu-Rin Kim and Minkook Son contributed equally to this study as co-first authors.
Received: 27 October 2025   • Revised: 23 December 2025   • Accepted: 4 January 2026
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OBJECTIVES
We evaluated the associations of smoking status, intensity, duration, and cumulative exposure with the risk of dental implant failure in Korean adults.
METHODS
This retrospective cohort study utilized the National Health Insurance Service–Health Screening Cohort (2016–2019). Overall, 23,573 individuals who had completed the dental implant process were included. Smoking status was categorized as non-smoker, ex-smoker, or current smoker. Smoking intensity, duration, and cumulative exposure were classified using standardized thresholds (>10 cigarettes per day, >10 years, and >10 pack-years). Implant failure was defined as reimplantation or removal. Cox proportional hazards models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for demographic, clinical, and behavioral covariates.
RESULTS
During follow-up, 605 implant failures occurred: 344 in non-smokers, 182 in ex-smokers, and 79 in current smokers. The corresponding incidence rates per 1,000 person-years were 11.56, 16.54, and 22.33, respectively. Current smoking was significantly associated with higher implant failure risk (adjusted HR, 1.59; 95% CI, 1.20 to 2.09), while ex-smokers displayed a non-significant increase (adjusted HR, 1.16; 95% CI, 0.94 to 1.45). A dose–response relationship was observed: smoking more than 10 cigarettes per day, smoking for more than 10 years, or exceeding 10 pack-years was associated with significantly increased risk.
CONCLUSIONS
Smoking is a significant, dose–dependent risk factor for dental implant failure in Korean adults. Current smokers have the highest risk; smoking cessation may reduce adverse outcomes. These findings emphasize the importance of detailed smoking assessments and cessation counseling in implant care and public health strategies.


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