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Original article Preventable cancer cases and deaths attributable to deficit of physical activity in Korea from 2015 to 2030
Soseul Sung1,2orcid , Sungji Moon1,3orcid , Jihye An5orcid , Jeehi Jung6orcid , Hyeon Sook Lee7orcid , Youjin Hong1,3orcid , Sangjun Lee1,3orcid , Woojin Lim1,2orcid , Kyungsik Kim1,3orcid , Inah Kim9orcid , Jung Eun Lee10orcid , Sun Ha Jee11orcid , Aesun Shin1,3orcid , Ji-Yeob Choi2,3orcid , Sun-Seog Kweon14orcid , Min-Ho Shin14orcid , Sangmin Park2,15orcid , Seung-Ho Ryu16orcid , Sun Young Yang17orcid , Seung Ho Choi17orcid , Jeongseon Kim18orcid , Sang-Wook Yi19orcid , Yoon-Jung Choi18orcid , Jeong-Soo Im20orcid , Hong Gwan Seo18,20orcid , Sohee Park11orcid , Kwang-Pil Ko1,21orcid , Sue K. Park1,3orcid
Epidemiol Health 2025;e2025010
DOI: https://doi.org/10.4178/epih.e2025010 [Accepted]
Published online: February 27, 2025
1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea
2Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea
3Cancer Research Institute, Seoul National University, Seoul, Korea
4Interdisciplinary Program in Cancer Biology, Seoul National University College of Medicine, Seoul, Korea
5Department of Epidemic Intelligence Service, Incheon Communicable Diseases Center, Incheon, Korea
6Department of Biomedicine & Health Science, The Catholic University of Korea, Seoul, Korea
7Incheon Public Health Policy Institute, Incheon, Korea
8Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea
9Department of Occupational and Environmental Medicine, Hanyang University College of Medicine, Seoul, Korea
10Department of Food and Nutrition, Seoul National University, Seoul, Korea
11Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea
12BK21plus Biomedical Science Project, Seoul National University College of Medicine, Seoul, Korea
13Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul, Korea
14Department of Preventive Medicine, Chonnam National University Medical School, Hwasun-gun, Jeollanam-do, Korea
15Department of Family Medicine, Seoul National University Hospital, Seoul, Korea
16Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
17Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea
18Graduate School of Cancer Science and Policy, National Cancer Center, Goyang-si, Gyeonggi-do, Korea
19Department of Preventive Medicine and Public Health, Catholic Kwandong University College of Medicine, Gangneung-si, Gangwon-do, Korea
20Division of Cancer Registration and Surveillance, National Cancer Center, Goyang-si, Gyeonggi-do, Korea
21Clinical Preventive Medicine Center, Seoul National University Bundang Hospital, Seongnam, Korea
Corresponding author:  Kwang-Pil Ko,
Sue K. Park,
Received: 24 July 2024   • Revised: 26 December 2024   • Accepted: 7 January 2025
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OBJECTIVES
This study aimed to determine the population–attributable fractions (PAFs) of cancers using various calculation methods and to estimate the PAFs of cancer incidence and mortality resulting from deficit in physical activity (DPA) from 2015 to 2030, based on data on prevalence rates.
METHODS
The PAF of cancer was estimated using a cohort study–based meta–analysis of relative risk (RR), national prevalence rates of DPA from 2000 to 2015, and national cancer statistics from 2015 to 2030, with a latency of 15 years.
RESULTS
In 2015, DPA contributed to 909 cancer cases and 548 deaths, accounting for 0.42% and 0.68% of new cancer cases and deaths, respectively. By 2030, the PAF values are expected to increase to 1.31% of incidence and 1.80% of mortality, with a continual increase from 2015 to 2030. When the low metabolic equivalent of task (MET) criteria were selected, the PAF values decreased for both incidence and mortality. The PAF calculated with <900 MET–min/week for the sex–specific MET criterion was higher than that calculated with <900 MET–min/week for both incidence and mortality.
CONCLUSIONS
The risk of cancer associated with DPA is expected to rise in both men and women. Future research and strategies should emphasize the promotion of physical activity for cancer prevention, considering its significant implications for public health.


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