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Original Article
Incidence of edentulism among older adults using the Korean National Health Insurance Service database, 2013-2018
Hyeonjeong Go1orcid, Eun-Kyong Kim2orcid, Hoi-In Jung3orcid, Song Vogue Ahn4orcid, Hosung Shin5orcid, Atsuo Amano6orcid, Youn-Hee Choi1,7orcid
Epidemiol Health 2022;44:e2022091.
DOI: https://doi.org/10.4178/epih.e2022091
Published online: October 17, 2022
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1Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea

2Department of Dental Hygiene, Kyungpook National University, Sangju, Korea

3Department of Preventive Dentistry and Public Oral Health, Yonsei University College of Dentistry, Seoul, Korea

4Department of Health Convergence, Ewha Womans University, Seoul, Korea

5Department of Social and Humanity in Dentistry, Wonkwang University School of Dentistry, Iksan, Korea

6Department of Preventive Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan

7Institute for Translational Research in Dentistry, Kyungpook National University, Daegu, Korea

Correspondence: Youn-Hee Choi Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177 Dalgubeol-daero, Jung-gu, Daegu 41940, Korea E-mail: cyh1001@knu.ac.kr
• Received: July 29, 2022   • Accepted: October 17, 2022

© 2022 Korea Disease Control and Prevention Agency.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Population aging is rapidly accelerating worldwide. Oral diseases related to aging are also on the rise. This study examined trends in the incidence of edentulism among the older Korean population using data from the Korean National Health Insurance Service (KNHIS).
    Data on older adults, aged ≥75 years of age, were obtained from the KNHIS for the period 2013-2018. Edentulism was defined as a treatment history of complete dentures in the KNHIS database. The exclusion criteria consisted of both disease codes and treatment codes related to conservative dental treatment, including periodontal and extraction treatment afterward. Crude incidence rates (CIRs) and age-standardized incidence rates (AIRs) with 95% confidence intervals were calculated and reported per 100,000 person-years by the direct method. Trends were tested by Cochrane Armitage models.
    Statistically significant increasing trends in both CIRs and AIRs were found among the older Korean population registered in the KNHIS (CIRs, 707.92 to 895.92; AIRs, 705.11 to 889.68; p<0.01). The incidence tended to increase in both genders (p<0.01). Both CIRs and AIRs in specific regions also showed slight but significant annual increases except for Jeju Island (p<0.01 or <0.05). The incidence showed increasing trends (p<0.01) in all income quintiles apart from the highest quintile. The edentulism incidence was highest in the lowest income group (the first quintile).
    Our data showed that the incidence of edentulism among the elderly showed an increasing trend from 2013 to 2018. This result provides a basis for future epidemiological studies on the incidence of edentulism in the older Korean population.
The worldwide aging population is rapidly accelerating. Globally, Korea is one of the world’s fastest aging countries, and fast becoming a “hyper-aging society,” in which the proportion of older adults aged 65 years and over exceeds 20%. Oral diseases related to aging are also on the rise. This is a cause for concern, as poor oral health generally lowers the quality of life. Edentulism is the state of complete tooth loss (i.e., not having a single natural tooth). Tooth loss can be explained not only as the cumulative effect of oral diseases, especially dental caries and periodontitis, but also as a result of treatment decisions [1,2] and the value placed on natural teeth. As such, both biological and social factors are involved in edentulism [3,4]. Edentulism leads to the deterioration of basic functions such as mastication, pronunciation, and facial appearance. Consequently, these changes can lead to insufficient food intake and poor nutrition [5-7], weight loss [8,9], increased risks of systemic diseases, and poor quality of life [10-13]. According to previous studies, when considering the number of years of loss due to poor health, disability or early death measured by disability-adjusted life years, severe tooth loss is considered a major disease burden for those aged 60 years or more [14-16]. According to the fourth Korea National Health and Nutrition Examination Survey (KNHANES) (2007-2009) conducted by the Korea Centers for Disease Control and Prevention (now known as the Korea Disease Control and Prevention Agency), the mean number of teeth in those aged 65-69 years and 75-79 years was 19.4 and 13.6, respectively [17]. Edentulism is a public health burden for older people and clearly affects primary care practices [18]. In Korea, removable complete and partial dentures, and dental implant services for the elderly population (aged ≥ 65) are provided by the Korean National Health Insurance Service (KNHIS). However, the oral disease burden among older individuals remains present due to gaps in health insurance coverage, which are frequently underestimated.
Previous surveys on trends in the prevalence of edentulism using national data have been conducted in different countries. For example, Slade et al. [19] assessed the trend of edentulism using data from national health surveys in the United States, and Cardoso et al. [20] reported the prevalence of edentulism from Brazil’s National Oral Health Survey. In Korea, Yu et al. [21] also reported the prevalence of edentulism among Korean adults using raw data from the KNHANES. However, studies on the incidence of edentulism are rare, and available research studies are mainly cross-sectional in design or time-series. These studies have limited sample sizes; thus, significant epidemiological relationships may not have been recognized. Longitudinal studies with large-scale sample sizes are warranted.
The purpose of this study was to further understand this process, guide policy decision-making, and provide support for expanding the coverage of health insurance. Thus, this study evaluated the incidence of edentulism in the 75-year and older population registered in the KNHIS. The results may be used as a reference for developing countermeasures and new polices.
Study design and data source
We conducted a retrospective population-based cohort study using the KNHIS-customized database from 2013 to 2018, which was the total period of the available dataset. The KNHIS database included records for the entire Korean population. It is a single-payer program that has covered the entire Korean population of approximately 50 million since 2002, through either the National Health Insurance System (97%) or Medical Aid (3%) [22,23]. The KNHIS-customized database contained records of dental and medical treatment information requested by researchers and collected by the National Health Insurance Corporation. The database is based on the date of the claim for the use of hospitals, clinics, and pharmacies, including national health insurance qualification data containing medical statements, disease codes, treatment codes, and prescription details, from 2002 to 2018. The disease codes in KNHIS were derived from the Korean Standard Classification of Disease, 7th revision, which was modified from the International Classification of Disease, 10th revision. The treatment classification according to Korean standard drug classification codes was also included.
Study population and the operational definition of edentulism
In this study, research was conducted using the total data, which included the elderly aged ≥ 75 from 2013 to 2018, when complete dentures were covered by insurance. To analyze trends in the incidence of complete edentulism in older adults, those with a history of complete dentures diagnosis and treatment from January 1, 2013 to December 31, 2018, were collected from the KNHIS-customized cohort data. The incidence of complete edentulism was calculated for older adults, aged 75 years or older, who were included within the study period and were covered by insurance benefits. The age for insurance benefits has expanded to those who are ≥ 75 years old from July 1, 2012, the population aged ≥ 70 years from July 1, 2015, and the over-65 population from July 1, 2016 (Figure 1). To compare the trend of incidence for each year on equal terms within a specified study period, older adults aged ≥ 75 years who were the subjects of insurance coverage for complete dentures throughout the entire study period, not those who aged ≥ 65, were selected.
As shown in Table 1, those with a K08.1 disease code as the diagnosis who received treatment corresponding to the included treatment codes, from January 1, 2013, to December 31, 2018, were regarded as edentulous patients. Those who were subsequently diagnosed with K02, K04, K05, or K08.3, which are related to teeth, and had treatment codes corresponding to the exclusion criteria, after complete denture treatment, were considered to have teeth and were excluded, as described in a previous study [24]. Furthermore, the deceased and those with missing data for relevant parameters were excluded.
Statistical analysis
We analyzed the frequency of receiving treatment of UA101-109 and UA501-509, corresponding to the first stage of complete denture treatment, from 2013 to 2018 among those with a K08.1 diagnosis. Of note, the insurance coverage period for complete dentures is once every 7 years [25]. Thus, cases that satisfied the diagnostic criteria of edentulism first occurred during the study period from 2013 to 2018. Therefore, we defined receiving a K08.1 diagnosis and who received treatment with a code of UA101-109 or UA501-509 as the first time point of edentulism. Using this definition, the incidence of edentulism among older Korean adults aged ≥ 75 years was investigated.
Based on the KNHIS-customized database, the incidence of edentulism per 100,000 people was calculated for each year. The incidence of edentulism by the total population, gender, regions, and income among older adults was also calculated. The incidence was calculated by dividing the number of edentulous patients with complete dentures by the total population of Koreans aged ≥ 75 years registered in the KNHIS annually as of the end of the year from the KNHIS Statistical Yearbook, and multiplying by 100,000.
Regions were divided into 10 categories: Seoul; Busan; Ulsan and South Gyeongsang Province ; Daegu and North Gyeongsang Province; Incheon and Gyeonggi Province; Gwangju and South Jeolla Province; Gangwon Province; North Chungcheong Province; South Chungcheong Province; Daejeon, North Jeolla Province, and Sejong ; and Jeju Special Self-Governing Province.
Income was divided into 5 quintiles. The lowest income segment was the first quintile (the lowest 20%). The highest income quintile was defined as the top 20%. Health insurance eligibility standards (head of household, family member, and Medical Aid beneficiaries) were also considered.
All statistical analyses were performed using SAS version 9.4 (SAS Institute Inc., Cary, NC, USA). The chi-square test was used to analyze descriptive statistics. Frequency data were presented as the number of cases (n) with percentage (%). Age-standardized incidence rates (AIRs) with 95% confidence intervals (CIs) were calculated and reported 100,000 person-years by the direct method [26]. Statistical significance in differences between crude incidence rates (CIRs) and AIRs was determined based on whether CIRs were included within the 95% CI of AIRs. The incidence trends were evaluated by the Cochran Armitage trend test.
Ethics statement
Institutional Review Board/Ethics Committee approval was obtained from the Wonkwang University Institutional Review Board (WKIRB-201911-SB-082), the Kyungpook National University Institutional Review Board (KNU-2021-0489), and the National Evidence-based Healthcare Collaborating Agency (NECAIRB21-009).
Table 2 shows the population of Koreans aged ≥ 75 insured through the KNHIS and trends in the incidence of edentulism. The number of older adults showed an average overall increase of 5.38% over the 6 years from 2013 to 2018. Both the CIRs and the AIRs of edentulism showed a statistically significant increasing trend (CIRs: 707.92 to 895.92; AIRs: 705.11 to 889.68; p< 0.01). The incidence slightly decreased in 2017 and increased in 2018. The average rate of change in the CIR of edentulism was 3.18% over the 6 years from 2013 to 2018, and that of the AIR was 3.06%. Between 2016 and 2017, the CIR decreased by 5.83% from 751.73 to 707.92 per 100,000 people, and then increased by 26.56% in 2018; the AIR decreased by 5.78% between 2016 and 2017, and then increased by 26.18% in 2018. The incidence gradually increased annually in both genders (p< 0.01), with a slightly higher incidence of edentulism in men than women. The annual average increase in incidence from 2013 to 2018 was 3.68% in men and 2.80% in women.
As shown in Table 3, both the CIRs and the AIRs significantly increased annually in each region except for Jeju Island (p< 0.01 or < 0.05). The average difference between the CIRs and AIRs was 1.16-fold, (125.23 per 100,000 persons) in Gwangju and South Jeolla Province, approximately 0.84-fold (-140.00 per 100,000 persons) in North Jeolla Province, and 0.94-fold (-65.07 per 100,000 persons) in Daegu and North Gyeongsang Province. In particular, Daegu and North Gyeongsang Province, and North Chungcheong Province showed higher edentulism incidence rates than other regions. In 2017, the edentulism incidence by region was generally lower than in the other years. The highest annual average rate of change in any region from 2013 to 2018 was a 9.55% increase in Daejeon, Chungcheongnam Province, and Sejong, while the rest of the regions showed increases of approximately 4%.
The incidence of edentulism showed an increasing trend between 2013 and 2018 in all quintiles except for the highest-income group (p< 0.01). The edentulism incidence was highest in the first quintile (the lowest income group) (Table 4). The annual average rate of change in edentulism incidence by income group from 2013 to 2018 was an increase of 2.65%.
This study examined the incidence of edentulism in the elderly Korean population (aged ≥ 75 years) from 2013 to 2018 using data from the KNHIS. Complete dentures were first covered by the KNHIS in July 2012. The incidence of edentulism among older adults gradually increased between 2013 and 2018. The edentulism incidence also differed by region. Furthermore, higher incidence was observed in lower-income quintiles.
In a recent study, edentulism in older adults (aged ≥ 80 years) showed an increasing trend from 2007 to 2017 [21]. Korea is moving toward an aging society with an increasingly older population, and the edentulism incidence among older Koreans in this study also slightly increased. According to Statistics Korea, the medical expenses per person aged ≥ 65 years continuously increase slightly every year [27]. The reason for the increase in medical expenses for the elderly is the increased prevalence of chronic diseases. Moreover, 70.9% of people with chronic diseases have 3 or more comorbid chronic diseases [28]. Many studies have shown that chronic systematic diseases and chronic periodontitis can cause tooth loss [29-33]. Thus, an increase in the number of older people with high levels of morbidity related to chronic diseases and the complex interactions between oral diseases and chronic diseases probably contributed to the increasing incidence trend of edentulism. Moreover, Silva-Junior et al. [1] reported a higher incidence of tooth loss in older adults within 4 years. Overall, the incidence of edentulism in older adults has shown a slightly increasing trend. As a result, greater efforts and different strategies are needed to achieve the “oral health in older adults” goal of Health Plan 2030.
Our results showed that there were more women than men in the older population. Conversely, men had a slightly higher incidence of edentulism than women. A recent study in Japan also found that men, who experienced more risk factors such as smoking, had a higher risk of tooth loss than women [34]. The authors observed that the incidence of edentulism among older adults was affected by residential region and income. Previous studies [35-37] have also reported that the number of people with tooth loss was associated with socioeconomic level. In this study, differences in the incidence between urban and rural regions were not analyzed because we did not perform the analysis according to the county (gun) level. However, we confirmed that the incidence of edentulism differed by units of cities and provinces. The edentulism incidence was the highest in Daegu and North Gyeongsang Province. This observation suggests that there is a need to develop better preventive oral health programs to improve the oral health of older adults living in that region. The annual average rate of change in the incidence of edentulism by region from 2013 to 2018 was the highest in Daejeon, South Chungcheong Province, and Sejong, at approximately 10%. Looking at income, our results showed that the edentulism incidence was the highest in the first quintile (lowest income group). According to a report presenting data from each region in Korea in 2017, the relative poverty of older adults in the bottom 20% of income rose somewhat in Daejeon and South Chungcheong Province [38]. This is speculated to have had some effects on the incidence of edentulism in that region, since edentulism is affected by financial conditions. To address this issue, government-led innovations in oral health policies, including effective oral health promotion among those with lower household incomes, are warranted.
The strengths of this study include the use of KNHIS data, as a representative population-based cohort dataset. The database used for analyses was large, extensive, and stable because it was constructed based on national health insurance data generated by the government or public institutions [22]. Therefore, these results can be used by policy-makers to create higher value-adding policies. Our results may also provide fundamental data for improving the oral health quality of life of older adults and ensure timely responses to a rapidly changing and aging society.
This study has several limitations. First, the operational definition of edentulism used in this study was based on health insurance records, not medical records. Since edentulism was not defined based on direct diagnoses from medical records and examinations, the results may have been underestimated. Therefore, further studies should be conducted to increase the sensitivity and specificity of the edentulism diagnosis for determining edentulism incidence. Second, we did not include data on treatments not covered by insurance. However, it became less common for older adults who paid out-of-pocket for uninsured dental treatment after the health insurance coverage of complete dentures [39]. Furthermore, invasive treatments such as dental implants or overdentures may be relatively limited in the older population (aged ≥ 75 years) because of their general health condition. Thus, the population in our study might have been less affected by these factors. Finally, since our analyses were based on data from the KNHIS, the increased incidence of edentulism may have been affected by the policy changes in insurance coverage that relate to oral health diseases and edentulism.
This data shows that the incidence of edentulism among older Korean adults, aged ≥ 75 years, registered in the KNHIS statistically significantly increased from 2013 to 2018 (i.e., since 2012, when complete dentures were first covered by the NHIS). Men had a slightly higher incidence of edentulism than women. Moreover, the incidence differed by region and income. Importantly, people in lower income quintiles had higher edentulism incidence. This result provides a basis for future epidemiological studies on the incidence of edentulism in the older population in Korea.


The authors have no conflicts of interest to declare for this study.


This work was supported by the Korea Health Industry Development Institute (KHIDI) grant funded by the Korean government (HI19C1218).


Conceptualization: Go H, Choi YH. Data curation: Go H, Jung HI, Ahn SV, Shin H, Choi YH. Formal analysis: Go H. Funding acquisition: Jung HI, Ahn SV, Shin H, Choi YH. Methodology: Go H, Choi YH. Project administration: Shin H, Choi YH. Visualization: Go H, Choi YH. Writing – original draft: Go H, Choi YH. Writing – review & editing: Kim EK, Jung HI, Ahn SV, Shin H, Amano A, Choi YH.

We would like to thank Yena Jeon from the Department of Statistics at Kyungpook National University for her assistance with the analysis.
Figure 1.
Description of the Korean National Health Insurance Service coverage of complete dentures in Korea. NHIS, National Health Insurance Service.
Table 1.
Inclusion and exclusion criteria by Korean Standard Classifica tion of Diseases, version 7 (KCD-7) codes1 for edentulism
Codes Criteria
Disease code1
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
Treatment codes2
UA101-109 Diagnosis and treatment plan for resin based complete denture
UA501-509 Diagnosis and treatment plan for metal based complete denture
Treatment codes2
U0002 Reamer of file
U0010 Simple treatment
U0011 Dental sedative filing
U0020 Pulp capping
U0041 Desensitizing treatment-topical application, iontophoresis
U0060 Access cavity preparation
U0074 Treatment for one visit filing
U0090 Pulpotomy
U0101 Pulp extirpation
U0111 Root canal irrigation
U0116 Root canal enlargement
U0119 Root canal shaping
U0121 Root canal filling with single cone method
U0126 Root canal filling with condensation method
U0131 Amalgam filling (1 surface)
U0132 Amalgam filling (2 surfaces)
U0133 Amalgam filling (3 surfaces)
U0134 Amalgam filling (≥4 surfaces)
U0135 Composite resin filling (1 surface)
U0136 Composite resin filling (2 surfaces)
U0137 Composite resin filling (3 surfaces)
U0138 Composite resin filling (≥4 surfaces)
U0140 Rubber dam application
U0151 Cavity preparation (1 surface)
U0152 Cavity preparation (2 surfaces)
U0153 Cavity preparation (3 surfaces)
U0154 Cavity preparation (≥4 surfaces)
U0220 Restoration polishing
U0210 Emergency pulp treatment
U0220 Recementation
U0239 Light curing composite resin restoration (1 surface)
U0240 Light curing composite resin restoration (2 surfaces)
U0241 Light curing composite resin restoration (≥3 surfaces)
UX001 Desensitizing treatment-laser treatment, dentin adhesive application
U2232 Scaling
U2233 Scaling before periodontal treatment
U4412 Extraction (anterior tooth)
U4413 Extraction (posterior tooth)
U4414 Extraction (complicated extraction)

1 The disease classification according to the KCD-7 was used.

2 The treatment classification according to the Korean standardized drug classification codes was used; After receiving a K08.1 disease code, patients with treatment codes for the disease codes of K02, KO4, KO5, KO83 (related to teeth) were considered to have teeth and excluded.

Table 2.
Trends in edentulism incidence in older adults aged 75 and over registered in the KNHIS
Year Incidence rate (per 100,000)**
Incidence case (n)
The no. of population1
CIR AIR (95% CI) Men Women Total Men Women Total Men Women
2013 742.31 1.00 (reference) 771.35 726.84 17,981 6,494 11,487 2,422,300 841,904 1,580,396
2014 779.86 778.20 (731.46, 753.16) 773.13 783.52 20,262 7,079 13,183 2,598,158 915,633 1,682,525
2015 784.41 781.38 (767.09 , 789.31) 802.08 774.62 21,576 7,861 13,715 2,750,617 980,075 1,770,542
2016 751.73 748.40 (770.25, 792.51) 779.60 735.99 22,031 8,248 13,783 2,930,709 1,057,981 1,872,728
2017 707.92 705.11 (737.50, 759.29) 736.23 691.50 22,448 8,569 13,879 3,170,983 1,163,908 2,07,75
2018 895.92 889.68 (877.80, 901.56) 958.27 859.29 29,724 11,765 17,959 3,317,714 1,227,729 2,089,985

KNHIS, Korean National Health Insurance Service; CIR, crude incidence rate; AIR, age-standardized incidence rate per 100,000 person-years; standard population 2013; CI, confidence interval.

1 The number of population as of the end of the year from the National Health Insurance Statistical Yearbook.

** p<0.01 for the Cochrane Armitage trend test.

Table 3.
Trend of edentulism incidence in older adults by residence
CIR AIR (95% CI) CIR AIR (95% CI) CIR AIR (95% CI) CIR AIR (95% CI) CIR AIR (95% CI) CIR AIR (95% CI)
Seoul** 482.18 1.00 (reference) 545.23 550.42 (526.86, 573.98) 528.39 525.76 (502.74, 548.79) 553.34 546.37 (522.90, 569.85) 498.70 492.27 (469.99, 514.55) 651.02 637.07 (611.72, 662.42)
Busan, Ulsan, South Gyeongsang Province** 955.27 - 955.53 989.16 (956.28, 1022.05) 966.57 985.21 (952.39, 1018.03) 915.00 923.53 (891.75, 955.30) 881.09 890.04 (858.85, 921.23) 1,068.75 1,060.07 (1,026.03, 1,094.12)
Daegu, North Gyeongsang Province* 994.61 - 1,006.77 1,110.20 (1,078.78, 1,141.61) 1,035.31 1,094.77 (1,063.57, 1,125.97) 947.68 979.99 (950.47, 1,009.51) 898.65 914.97 (886.45, 943.49) 1,131.75 1,153.91 (1,121.87, 1,185.94)
Incheon-Gyeonggi Province** 584.79 - 619.39 659.85 (637.79, 681.91) 630.24 647.80 (625.94, 669.66) 601.30 612.04 (590.80, 633.29) 580.64 586.12 (565.32, 606.91) 735.88 747.40 (723.92, 770.88)
Gwangju, South Jeolla Province* 808.71 - 897.91 795.60 (757.67, 833.53) 770.85 773.63 (736.22, 811.03) 868.01 747.65 (710.88, 784.42) 789.91 682.80 (647.66, 717.94) 1,016.64 868.43 (828.80, 908.06)
North Jeolla Province** 619.17 - 716.61 875.83 (825.25, 926.40) 817.05 815.73 (766.91, 864.54) 689.64 831.43 (782.15, 880.71) 649.96 770.70 (723.25, 818.14) 824.96 963.23 (910.18, 1,016.27)
Gangwon Province** 770.52 - 897.53 941.87 (879.84, 1003.90) 895.85 926.65 (865.12, 988.18) 897.44 919.25 (857.92, 980.53) 799.91 812.08 (754.48, 869.68) 966.36 970.15 (907.19, 1,033.10)
North Chungcheong Province** 950.10 - 905.18 964.66 (899.59, 1029.72) 1020.13 1,043.78 (976.10, 1111.46) 876.81 905.89 (842.84, 968.93) 898.18 925.21 (861.50, 988.93) 1,148.79 1,148.25 (1,077.27, 1,219.24)
Daejeon, South Chungcheong Province, Sejong** 578.40 - 846.07 814.86 (775.45, 854.26) 832.64 796.87 (757.91, 835.84) 796.05 742.78 (705.16, 780.40) 736.07 726.18 (688.98, 763.37) 999.57 977.94 (934.77, 1,021.10)
Jeju Island 724.38 - 750.99 775.55 (678.62, 872.48) 814.92 832.95 (732.49, 933.40) 723.72 727.07 (633.22, 820.92) 662.53 657.52 (568.27, 746.77) 800.78 774.54 (677.67, 871.40)

CIR, crude incidence rate; AIR, age-standardized incidence rate per 100,000 person-years; standard population 2013; CI, confidence interval.

* p<0.05,

** p<0.01 for the Cochrane-Armitage trend test.

Table 4.
Trends in edentulism incidence among older adults by income distribution1
Year First quintile** Second quintile** Third quintile** Fourth quintile** Fifth quintile
2013 829.81 777.82 798.99 759.97 743.05
2014 865.07 853.66 811.88 780.18 761.43
2015 794.33 864.78 828.31 809.83 772.93
2016 822.63 808.00 780.12 760.87 704.71
2017 744.43 747.76 737.61 715.01 671.99
2018 962.51 931.38 955.99 904.23 824.25

Rates are given per 100,000 person-years.

1 The lowest income segment (the bottom 20% of income) was the first quintile, and the highest quintile corresponded to the top 20% of income.

** p<0.01 for the Cochrane-Armitage trend test.

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