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The 2019 Rio Grande birth cohort: profile of a Brazilian 5-year study on mental health conditions
Rafaela Costa Martins, Francine dos Santos Costa, Cauane Blumenberg, Thais Martins-Silva, Romina Buffarini, Juraci Almeida Cesar, Christian Loret de Mola
Epidemiol Health. 2025;47:e2025039.   Published online July 21, 2025
DOI: https://doi.org/10.4178/epih.e2025039
  • 5,222 View
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  • 2 Web of Science
  • 1 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
We established the 2019 Rio Grande birth cohort to investigate the life course epidemiology of mental health and its intergenerational transmission. In 2019, we systematically identified all hospital births in the city of Rio Grande, located in Southern Brazil. Mothers who delivered a singleton liveborn child were administered a standardized, face-to-face questionnaire. In 2020, we conducted 2 follow-up assessments (WebCOVID-19 1 and 2), a third in 2021-22 (WebCOVID-19-3), and a fourth in 2023-24 (WebPOST-COVID). Across these follow-ups, we collected data on socio-demographic, environmental, and behavioral factors pertaining to both mother and child, as well as maternal mental health. Child mental health and development were specifically evaluated during the fourth follow-up. At baseline, 2,051 mothers were interviewed. Response rates for the online follow-ups were 54.1%, 51.1%, 48.7%, and 34.6%, respectively. In WebCOVID-19-3, the highest prevalence rates for depression (34.7%) and anxiety (33.1%) were observed. This cohort provides novel insights into maternal mental health, child development, and post-coronavirus disease 2019 behaviors, emphasizing culturally specific risk factors. Our findings are based on both published and ongoing studies. Data may be requested upon reasonable request.
Summary
Key Message
The 2019 Rio Grande Birth Cohort is a prospective study that has been following over 2,000 mothers and their children since 2019. It is designed specifically to understand the intergenerational transmission of mental health problems. The cohort's unique design combines detailed face-to-face questionnaires at baseline with remote, web-based follow-ups, and serves as a comprehensive overview of the cohort's methodology, data collection instruments, and study design, demonstrating its potential to generate valuable insights into maternal and child health.

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  • Changes in habits among mothers during the period of social isolation due to COVID-19 in the municipality of Rio Grande, Rio Grande do Sul, Brazil
    Jefferson Sales da Silva, Pâmela Moraes Volz, Rafaela Costa Martins, Francine dos Santos Costa, Cauane Blumenberg, Thais Martins Silva, Romina Buffarini, Lorena Goulart Vieira, Patricia Cota Lima, Zulema Mamani Condori, Caroline Lisset Dominguez Herido, C
    Revista Brasileira de Epidemiologia.2025;[Epub]     CrossRef
Brief Communication
The association between employee lifestyles and the rates of mental health-related absenteeism and turnover in Japanese companies
Atsuya Fujimoto, Hiroshi Kanegae, Kaori Kitaoka, Mizuki Ohashi, Kunio Okada, Koichi Node, Kenkichi Takase, Hiroshi Fukuda, Tomoyuki Miyazaki, Yuichiro Yano
Epidemiol Health. 2024;46:e2024068.   Published online August 2, 2024
DOI: https://doi.org/10.4178/epih.e2024068
  • 16,237 View
  • 290 Download
  • 1 Web of Science
  • 1 Crossref
AbstractAbstract PDF
Abstract
We assessed the association of employee lifestyles (e.g., smoking, exercise, drinking, and sleep habits) with mental health-related absenteeism and turnover rates utilizing data from the annual Health and Productivity Management survey by Japan’s Ministry of Economy, Trade and Industry. This analysis included data from 1,748 companies, encompassing 4,199,021 employees. The average proportions of mental health-related absenteeism and employee turnover rates were 1.1±1.0% and 5.0±5.0%, respectively. In multivariable regression models that incorporated all lifestyle factors and confounders, a 1 percentage point increase in the proportion of employees who slept well was associated with reductions in their turnover rate (mean, -0.020%; 95% confidence interval [CI], -0.038 to -0.002) and in mental health-related absenteeism (mean, -0.005%; 95% CI, -0.009 to 0.001). A similar increase in the proportion of employees engaging in regular physical activity corresponded with a 0.005% decrease in the prevalence of mental health-related absenteeism (95% CI, -0.010 to -0.001). A 1 percentage point increase in the proportion of employees who smoked was associated with a 0.013% reduction in mental health-related absenteeism (95% CI, -0.017 to -0.008). Nonetheless, the current study’s observational and cross-sectional design restricted the ability to establish causality between employee lifestyle factors and mental health issues.
Summary

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  • Telemonitored sleep quality and daily activity are associated with mental health outcomes among Japanese workers
    Seiko Miyata, Kunihiro Iwamoto, Keita Kawai, Hiroshige Fujishiro, Kazuyuki Nakagome, Norio Ozaki, Masashi Ikeda
    Scientific Reports.2026;[Epub]     CrossRef
Original Articles
Association of healthy lifestyle factors with the risk of hypertension, dyslipidemia, and their comorbidity in Korea: results from the Korea National Health and Nutrition Examination Survey 2019-2021
Ji-Sook Kong, Mi Kyung Kim
Epidemiol Health. 2024;46:e2024049.   Published online May 1, 2024
DOI: https://doi.org/10.4178/epih.e2024049
  • 16,335 View
  • 304 Download
  • 3 Web of Science
  • 4 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
We investigated the association of individual healthy lifestyle factors (HLFs) and their combined healthy lifestyle score (HLS) with hypertension and/or dyslipidemia.
METHODS
We analyzed data from 10,693 adults aged ≥19 from the 2019 to 2021 Korea National Health and Nutrition Examination Survey. HLS was evaluated based on smoking status, alcohol consumption, body mass index (BMI), diet, and physical activity. Using logistic regression models, we estimated odds ratios (ORs) with 95% confidence intervals (CIs) to evaluate the associations of HLFs and HLS with hypertension, dyslipidemia, and their comorbidity.
RESULTS
The prevalence of hypertension alone, dyslipidemia alone, and their comorbidity was 8.7%, 24.6%, and 15.0%, respectively. Multivariable models showed an inverse association of hypertension (OR, 0.37; 95% CI, 0.30 to 0.46) and dyslipidemia (OR, 0.36; 95% CI, 0.32 to 0.41) with healthy BMI. Hypertension was inversely associated with healthy alcohol consumption (OR, 0.46; 95% CI, 0.35 to 0.61) and diet (OR, 0.79; 95% CI, 0.63 to 0.99), whereas dyslipidemia was inversely associated with non-smoking (OR, 0.51; 95% CI, 0.43 to 0.60). Physical activity was inversely associated with their comorbidity (OR, 0.69; 95% CI, 0.56 to 0.85). Adherence to HLS was associated with significantly lower odds of hypertension (81%), dyslipidemia (66%), and their conditions (89%) (all ptrend<0.001). Stratified analyses consistently showed inverse associations between HLS and hypertension and/or dyslipidemia independently of demographic factors (pinteractions>0.05).
CONCLUSIONS
HLFs were associated with lower risk for hypertension and/or dyslipidemia. Obesity may contribute significantly to the risk of these conditions, while relevant HLFs for individual chronic diseases may vary significantly.
Summary
Korean summary
건강한 생활 습관 요인(HLFs)의 개별 구성 요인들은 고혈압 및 이상지질혈증의 동반 위험과 각각의 상태와 음의 연관성을 보였다. 다양한 HLFs 중에서 BMI 상태가 중요한 요인으로 확인되었지만, 개별 만성 질환에 대한 관련 HLFs는 상당히 다를 수 있다. 또한, 명확한 용량-반응 관계가 관찰되어, 더 HLFs를 준수할수록 고혈압, 이상지질혈증 및 그들의 동반 가능성이 유의미하게 감소하는 것으로 나타났다.
Key Message
Individual components of healthy lifestyle factors (HLFs) were inversely associated with the risk of comorbid hypertension and dyslipidemia, as well as with each condition. Among the various HLFs, BMI status was identified as a significant factor, while relevant HLFs for individual chronic diseases may vary significantly. Additionally, clear dose-response associations were observed, indicating that adherence to more HLFs was significantly associated with decreasing odds of hypertension, dyslipidemia, and their comorbidity.

Citations

Citations to this article as recorded by  
  • The associations between healthy lifestyle scores, their long-term changes, and incident hypertension risk in adults: a prospective cohort study
    Ji Zhang, Tao Liu, Yanli Wu, Jie Zhou, Ling Li, Xuejiao Li, Wei Ji
    Frontiers in Cardiovascular Medicine.2026;[Epub]     CrossRef
  • Association between lifestyle changes and metabolic syndrome: a prospective cohort study in middle-aged Koreans
    Kyoungsik Jeong, Hoseok Kim, Siwoo Lee, Younghwa Baek
    BMJ Open.2026; 16(2): e102058.     CrossRef
  • Prevalence of dyslipidemia and its associated risk factors in hypertensive population: A single-center cross-sectional study in southern China
    Junming Sun, Bin Huang, Weikun Zhao, Qiurui Li, Siwei Yin, Ying Zhang, Rongjie Huang
    Journal of the Renin-Angiotensin-Aldosterone System.2025;[Epub]     CrossRef
  • Nutriomics and artificial intelligence nutrition obesity cohort (NAINOC): a design paper for a prospective cohort for nutrition and obesity research
    Minyoung Lee, Sungha Park, Soo-Hyun Park, Ho-Young Park, Yu Ra Lee, Min-Sun Kim, Miso Nam, Jangho Lee, Hyein Seo, Yong-ho Lee, Chan Joo Lee, Jae-Ho Park, Hye Hyun Yoo, Hyun-Jin Kim, Kyong-Oh Shin, Yoshikazu Uchida, Kyungho Park
    Clinical Hypertension.2025;[Epub]     CrossRef
Adherence to the American Cancer Society guidelines on nutrition and physical activity for cancer survivors and biomarkers of inflammation among breast cancer survivors
Minji Kang, Sihan Song, Hyun Jeong Cho, Zisun Kim, Hyun Jo Youn, Jihyoung Cho, Jun Won Min, Yoo Seok Kim, Sang-Woon Choi, Jung Eun Lee
Epidemiol Health. 2024;46:e2024026.   Published online January 25, 2024
DOI: https://doi.org/10.4178/epih.e2024026
  • 15,940 View
  • 213 Download
  • 3 Web of Science
  • 3 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study investigated whether adherence to the overall lifestyle recommendations in the American Cancer Society (ACS) guidelines on nutrition and physical activity for cancer survivors was associated with inflammation in breast cancer survivors.
METHODS
The study included 409 women who had undergone breast cancer surgery at least 1 year before enrollment. A generalized linear model was used to estimate the least square means and 95% confidence intervals of plasma levels of inflammatory markers according to lifestyle factors defined in terms of adherence to the ACS guidelines.
RESULTS
Higher overall adherence scores were associated with lower levels of high-sensitivity C-reactive protein (hs-CRP) (p for trend=0.015) and higher levels of adiponectin (p for trend=0.009). Similar significant associations of hs-CRP (p for trend= 0.004) and adiponectin (p for trend=0.010) levels were observed with the score for the body mass index (BMI) component of the adherence score. A higher diet component score was associated with a higher adiponectin level (p for trend=0.020), but there was no significant association for the physical activity component score.
CONCLUSIONS
The present study’s findings suggest that maintaining a healthy lifestyle according to the ACS guidelines was associated with beneficial effects on inflammatory marker levels, especially hs-CRP and adiponectin, among breast cancer survivors. Among the 3 components of lifestyle guidelines, the BMI component exhibited the most similar tendency to the overall adherence score in relation to inflammatory indicators. Further prospective and intervention studies are needed to investigate longitudinal associations between lifestyle factors and inflammatory markers among breast cancer survivors.
Summary
Korean summary
- 한국인 유방암 생존자를 대상으로 한 연구에서, 암 생존자를 위한 영양 및 신체 활동에 관한 미국암협회 (American Cancer Society, ACS) 지침을 따라 건강한 생활 습관을 유지하는 것이 혈중 염증 마커 수준, 특히 낮은 hs-CRP와 높은 adiponectin 수준과 관련이 있었습니다.
- 체질량지수 (Body Mass Index, BMI)를 적절한 수준 (18.5-23 kg/m²)으로 유지하는 것은 낮은 hs- CRP 수준과 높은 adiponectin 수준과 관련이 있는 것으로 나타났습니다.
- 또한, 과일, 야채 및 통곡물이 풍부하고 적색육 및 가공육을 적게 섭취하는 건강한 식단은 혈중 adiponectin 수치가 높은 것과 관련이 있었습니다.
Key Message
• Maintaining a healthy lifestyle according to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Survivors was associated with favorable levels of inflammatory markers, especially in hs-CRP and adiponectin among breast cancer survivors.
• Maintaining an adequate BMI of 18.5 to 23 kg/m2 was associated with lower levels of hs-CRP and higher adiponectin levels.
• In addition, a healthy diet — indicating a diet high in fruits, vegetables, and whole grains, and low in red and processed meats — was associated with higher adiponectin levels.

Citations

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  • Dietary isoflavone intake among breast cancer survivors and cancer-free women
    Sihan Song, Hyeong-Gon Moon, Dong-Young Noh, So-Youn Jung, Eun Sook Lee, Zisun Kim, Hyun Jo Youn, Jihyoung Cho, Young Bum Yoo, Se Kyung Lee, Jeong Eon Lee, Seok Jin Nam, Yoo Seok Kim, Jun Won Min, Shinyoung Jun, Hyojee Joung, Jung Eun Lee
    Nutrition Research and Practice.2025; 19(1): 80.     CrossRef
  • Dietary intake and plasma isoflavones are inversely associated with inflammatory markers in breast cancer survivors: A cross-sectional study
    Sihan Song, Zisun Kim, Hyun Jo Youn, Jihyoung Cho, Yoo Seok Kim, Jun Won Min, Sang-Woon Choi, Adrian A. Franke, Shinyoung Jun, Hyojee Joung, Jung Eun Lee
    Nutrition Research.2025; 138: 22.     CrossRef
  • Adherence to the Mediterranean diet and mortality in cancer survivors: a Nationwide study with mediation and subgroup analyses
    Bowen Zha, Lizhou Dou, Chen Zhang, Shun He, Guiqi Wang
    Frontiers in Nutrition.2025;[Epub]     CrossRef
Socioeconomic inequality in health-related quality of life among Korean adults with chronic disease: an analysis of the Korean Community Health Survey
Thi Huyen Trang Nguyen, Thi Tra Bui, Jinhee Lee, Kui Son Choi, Hyunsoon Cho, Jin-Kyoung Oh
Epidemiol Health. 2024;46:e2024018.   Published online January 8, 2024
DOI: https://doi.org/10.4178/epih.e2024018
  • 14,120 View
  • 128 Download
  • 2 Web of Science
  • 4 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
Health-related quality of life is crucial for people dealing with chronic illness. This study investigated the quality of life in individuals with 5 common chronic conditions in Korea. We also analyzed socioeconomic factors such as education, income, occupation, and urbanization to identify determinants of inequality.
METHODS
Using 2016 Korea Community Health Survey data, we examined individuals aged 30 or older with chronic diseases (diabetes, hypertension, cardiovascular disease, hyperlipidemia, arthritis) using the EuroQol 5-Dimension 3 Level tool. We analyzed the associations between socioeconomic factors (education, income, occupation, urbanization) and quality of life using descriptive statistics and regression analysis. Inequality indices (relative inequality index, absolute inequality index) were used to measure inequality in quality of life.
RESULTS
Individuals with higher income levels showed a 1.95-fold higher likelihood of a better quality of life than those with the lowest income. The lowest income group had higher odds of mobility (adjusted odds ratio [aOR], 2.2), self-care (aOR, 2.1), activity limitations (aOR, 2.4), pain/discomfort (aOR, 1.8), and anxiety/depression (aOR, 2.3). Educational disparities included a 3-fold increase in mobility and daily activity problems for those with elementary or lower education. Well-educated participants had a 1.94 times higher quality of life, with smaller differences in anxiety/depression and self-management. The income gap accounted for 14.1% of variance in quality-of-life disparities.
CONCLUSIONS
Addressing socioeconomic disparities in the quality of life for individuals with chronic diseases necessitates tailored interventions and targeted health policies. This research informs policymakers in developing focused initiatives to alleviate health inequities. It emphasizes the importance of mental health support and ensuring affordable, accessible healthcare services.
Summary
Korean summary
- 지역사회건강조사 자료를 통해 확인한 한국인에게 호발하는 만성질환자(당뇨, 고혈압, 심혈관질환, 고지혈증, 관절염)에서 삶의 질 점수(EQ-5D)는 평균 0.7점으로, 남성에서 높고, 연령이 높을수록 낮다. - 소득이 낮거나 교육수준이 낮은 군에서 삶의 질이 상대적으로 낮으며, 특히 운동능력, 자기관리, 통증/불편, 불안/우울 각각에서 두배 가량 어려움을 겪는 것으로 나타났다. - 만성질환자에서 삶의 질은 사회경제적 여건에 따라 격차가 존재하므로, 취약한 계층 발굴과 지원이 필요하다.
Key Message
- Quality of life score (EQ-5D) in patients with chronic diseases (i.e., diabetes, hypertension, cardiovascular disease, hyperlipidemia, and arthritis) that are prevalent in Koreans identified through data from community health surveys averaged 0.7, lower in women than in men, and decreased by age. - Low-income or low-educated patients have relatively low quality of life, and they have more than twice as much problem in mobility, self-care, pain/discomfort, and anxiety/depression. - Disparities in quality of life in patients with chronic diseases according to socioeconomic conditions have been found, and support for the vulnerable is needed.

Citations

Citations to this article as recorded by  
  • Association between obstructive sleep Apnea–Related factors and HINT-8 utility scores in adults: a secondary analysis of the 2023 Korea National health and nutrition examination survey (KNHANES)
    Mima Park, Seon-Ha Kim
    Quality of Life Research.2026;[Epub]     CrossRef
  • Analysis of asthma incidence and mortality rates among children aged 0–14 in 204 countries from 1990 to 2019
    Fei Cheng, Li He, Dachuan Deng, Jinhui Zhang, Cheng Liu
    Journal of Asthma.2025; 62(1): 45.     CrossRef
  • Feasibility of Using the EuroQol-5 Dimensions to Identify Masticatory Discomfort in Community-Dwelling Older Adults
    Han-Nah Kim, Nam-Hee Kim
    Journal of Dental Hygiene Science.2025; 25(3): 237.     CrossRef
  • Health-related Quality of Life in Multimorbid Adults: A Random Forest Cross-sectional Analysis of the Korean National Health and Nutrition Examination Survey
    Moonchang You, Geun-Myun Kim
    Journal of Korean Academy of psychiatric and Mental Health Nursing.2025; 34(3): 349.     CrossRef
Determinants of unhealthy living by gender, age group, and chronic health conditions across districts in Korea using the 2010-2017 Community Health Surveys
Thi Tra Bui, Thi Huyen Trang Nguyen, Jinhee Lee, Sun Young Kim, Jin-Kyoung Oh
Epidemiol Health. 2024;46:e2024014.   Published online January 4, 2024
DOI: https://doi.org/10.4178/epih.e2024014
  • 14,114 View
  • 136 Download
  • 2 Web of Science
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
We investigated the prevalence and determinants of unhealthy living by gender, age, and comorbidities across Korean districts.
METHODS
For 806,246 men and 923,260 women from 245 districts who participated in the 2010-2017 Korean Community Health Surveys, risk scores were calculated based on obesity, physical inactivity, smoking, and high-risk alcohol consumption, each scored from 0 (lowest risk) to 2 (highest risk). A risk score ≥4 was defined as indicating unhealthy living, and weighted proportions were calculated for each district. Using multivariate regression, an ecological model including community socioeconomic, interpersonal, and neighborhood factors was examined by gender, age, and comorbidities.
RESULTS
The mean age-standardized rate of unhealthy living was 24.05% for men and 4.91% for women (coefficients of variation, 13.94% and 29.51%, respectively). Individuals with chronic diseases more frequently exhibited unhealthy lifestyles. Unhealthy lifestyles were associated with educational attainment (β-coefficients: men, -0.21; women, -0.15), high household income (β=0.08 and 0.03, respectively), pub density (β=0.52 and 0.22, respectively), and fast-food outlet density (β=2.81 and 1.63, respectively). Negative associations were observed with manual labor, social activity participation, and hospital bed density. Unhealthy living was positively associated with living alone among women and with being unemployed among middle-aged men. Access to parks was negatively associated with unhealthy living among young men and women. The ecological model explained 32% of regional variation in men and 41% in women.
CONCLUSIONS
Improving the neighborhood built and socioeconomic environment may reduce regional disparities in lifestyle behaviors; however, the impacts may vary according to socio-demographic traits and comorbidities.
Summary
Korean summary
- 시군구 지역단위의 불건강생활(흡연, 음주, 비만, 신체활동 부족 각 0-2점, 합 4점 이상 불건강) 유병률은 여자보다 남자에서 높고, 연령이 높아지면서 감소한다. - 지역사회 환경개선(술집 개수, 패스트푸드점 밀도, 공원 면적, 병상밀도)과 사회경제적 수준 강화(교육수준, 가구소득, 고용)를 통해 생활습관적 건강행태의 지역 격차를 줄일 수 있다. - 이러한 향상 노력의 효과는 지역의 건강상태 수준이나 사회인구학적 특성에 따라 다를 수 있다.
Key Message
• District prevalence rates of unhealthy living were higher among men than women and decreased with advancing age. • Efforts to reduce regional disparities in lifestyle behaviors could benefit from enhancements to the neighborhood environment and the socioeconomic status of the area. • The effectiveness of such improvements may vary based on socio-demographic characteristics and health conditions.

Citations

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  • Interactive Digital Visualization Counseling for Lifestyle Change in Patients at Risk of Cardiovascular Diseases: Randomized Controlled Trial
    Adrijana Svenšek, Mateja Lorber, Zalika Klemenc-Ketiš, Lucija Gosak, Dominika Muršec, Gregor Štiglic
    JMIR Public Health and Surveillance.2026; 12: e83488.     CrossRef
  • A Community-Based, Lifestyle Behavioral Intervention Based on the Extended Theory of Planned Behavior for Postmenopausal Women at Cardiometabolic Risk: A Randomized Controlled Trial
    Sooyeon Park, Jina Choo
    Western Journal of Nursing Research.2025; 47(7): 573.     CrossRef
  • Feasibility of Using the EuroQol-5 Dimensions to Identify Masticatory Discomfort in Community-Dwelling Older Adults
    Han-Nah Kim, Nam-Hee Kim
    Journal of Dental Hygiene Science.2025; 25(3): 237.     CrossRef
Age-specific findings on lifestyle and trajectories of cognitive function from the Korean Longitudinal Study of Aging
Seungju lim, Eunyoung Yoo, Ickpyo Hong, Ji-Hyuk Park
Epidemiol Health. 2023;45:e2023098.   Published online November 2, 2023
DOI: https://doi.org/10.4178/epih.e2023098
  • 15,089 View
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  • 8 Web of Science
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AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
Few longitudinal studies have explored age-related differences in the relationship between lifestyle factors and cognitive decline. This study investigated lifestyle factors at baseline that slow the longitudinal rate of cognitive decline in young-old (55-64 years), middle-old (65-74 years), and old-old (75+ years) individuals.
METHODS
We conducted an 11-year follow-up that included 6,189 older adults from the Korean Longitudinal Study of Aging, which is a cohort study of community-dwelling older Koreans. Lifestyle factors, including physical activity, social activity (SA), smoking, and alcohol consumption were assessed at baseline. Cognitive function was measured at 2-year intervals over 11 years. Latent growth modeling and multi-group analysis were performed.
RESULTS
The influence of lifestyle factors on the rate of cognitive decline differed by age. Smoking at baseline (-0.05; 95% confidence interval [CI], -0.11 to -0.00, per study wave) accelerated cognitive decline in young-old individuals, whereas frequent participation in SA at baseline (0.02; 95% CI, 0.01 to 0.03, per study wave) decelerated cognitive decline in middle-old individuals. None of the lifestyle factors in this study decelerated cognitive decline in old-old individuals.
CONCLUSIONS
Cognitive strategies based on modifiable lifestyle factors such as smoking cessation in young-old individuals and frequent SA participation in middle-old age individuals may have great potential for preventing cognitive decline. Because the influence of lifestyle factors varied by age group, age-specific approaches are recommended to promote cognitive health.
Summary
Korean summary
본 연구는 국내 노인인구를 연령대별로 구분하여 연소노인(55-64세), 중고령노인(65-74세), 고령노인(75세+)의 인지저하 기울기를 가속 혹은 감속시키는 라이프스타일 요인을 파악하였다. '흡연'은 연소노인의 인지저하를 가속, '사회활동 참여 빈도'는 중고령노인의 인지저하를 감속시키는 것으로 나타났으며, 고령노인의 경우 유의미한 변수가 나타나지 않았다. 본 결과는 노인의 인지건강에 있어 연령대별 차별화된 라이프스타일 전략이 필요할 것을 시사한다.
Key Message
This study aimed to identify lifestyle factors that accelerate or decelerate the cognitive decline slope in the older population in South Korea, categorized by age groups: young-old adults (55-64), middle-old adults (65-74), and old-old adults (75+). The findings indicated that 'smoking' accelerates cognitive decline in young-old adults, while 'frequency of social activity participation' decelerates cognitive decline in middle-old adults. However, no significant lifestyle variables were identified for old-old adults. These results suggest the necessity of differentiated lifestyle strategies based on age groups for promoting cognitive health in the older population.

Citations

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  • Predictive roles of oral and mental health among Korean older adults experiencing functional cognitive impairment: A secondary data analysis from the 2019 Community Health Survey
    Kyungae Kim
    Medicine.2026; 105(1): e46141.     CrossRef
  • A rapid scoping review on operationalizing cognitive and social activities in research on dementia risk reduction
    Jeroen Bruinsma, Ruud Roodbeen, Giselle G. A. Menting, Kay Deckers, Stevie Hendriks, Rik Crutzen
    Aging & Mental Health.2025; 29(10): 1788.     CrossRef
  • Genetic association of social participation with cognitive function: A bidirectional Mendelian randomization study
    Aoqiang Zhai, Ruiqi Zou, Tianrun Lv, Siqi Yang, Yanjie Zhong, Yang Xiong, Fuyu Li, Haijie Hu
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    Jingjuan Pang, Minghui Li, Zhaorui Liu, Yueqin Huang, Xiaofei Hou, Guoli Yan, Xiangdong Xu, Limin Wang, Yongping Yan, Shuiyuan Xiao, Lingjiang Li, Jie Yan, Yaqin Yu, Xiufeng Xu, Zhizhong Wang, Yifeng Xu, Tao Li, Tingting Zhang, Huifang Yin, Guangming Xu
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    Jeroen Bruinsma, Leonie N. C. Visser, Alara Abaci, Anna Rosenberg, Ana Diaz, Sten Hanke, Rik Crutzen, Francesca Mangialasche, Miia Kivipelto, Charlotta Thunborg
    Frontiers in Psychiatry.2024;[Epub]     CrossRef
  • Association between dietary quality and accelerated aging: a cross-sectional study of two cohorts
    Yue Chen, Xin Zheng, Yiming Wang, Chenan Liu, Jinyu Shi, Tong Liu, Shiqi Lin, Hailun Xie, Heyang Zhang, Xiaoyue Liu, Zhaoting Bu, Li Deng, Shouling Wu, Hanping Shi
    Food & Function.2024; 15(15): 7837.     CrossRef
  • Independent and Joint Associations of Socioeconomic Status and Lifestyle behaviors with Cognitive Impairment among Elderly Chinese Population
    Y. Feng, S. Jia, W. Zhao, X. Wu, Y. Zuo, S. Wang, L. Zhao, M. Ma, X. Guo, C.S. Tarimo, Y. Miao, Jian Wu
    The Journal of Prevention of Alzheimer's Disease.2024; 11(5): 1513.     CrossRef
Special Article
Limiting the spillover of zoonotic pathogens from traditional food markets in developing countries and a new market design for risk-proofing
Sandeep Ghatak, Kandhan Srinivas, Arockiasamy Arun Prince Milton, Govindarajan Bhuvana Priya, Samir Das, Johanna F. Lindahl
Epidemiol Health. 2023;45:e2023097.   Published online October 30, 2023
DOI: https://doi.org/10.4178/epih.e2023097
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AbstractAbstract AbstractSummary PDF
Abstract
Traditional food markets are age-old systems that primarily serve the food supply needs of society’s less affluent sectors, often operating with minimal infrastructure. These markets are prevalent in low and middle-income countries. However, their hygienic conditions are frequently suboptimal, potentially fostering the emergence and spread of presumptive zoonotic diseases. The recent emergence of zoonotic or potentially zoonotic diseases and their possible links to traditional food markets underscore the need for focused attention on this overlooked issue. The socioeconomic characteristics of traditional food markets reveal that despite the risk of zoonotic pathogen spread, these markets play a crucial role for large segments of the population. These individuals rely on such markets for their livelihood, food, and nutrition. Therefore, a comprehensive set of measures addressing various aspects of traditional food markets is necessary to manage and mitigate the risks of potential zoonotic disease emergence. In this article, we explore various facets of traditional food markets, paying special attention to the risks of zoonotic diseases that urgently require stakeholder attention. We also propose a new market design to prevent the risk of zoonotic spillover and advocate for the development of a Market Hygiene Index for these markets.
Summary
Key Message
Embracing Tradition, Ensuring Safety! Traditional food markets are vital for many communities, supplying food and livelihoods. Yet, their suboptimal hygiene poses potential risks for zoonotic diseases. Our article sheds light on the importance of addressing this issue and offers a new market design for risk-proofing in developing countries. Join the conversation on safeguarding these markets and support the vulnerable for a safer, healthier future!

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  • Prevalence of bacterial contamination on seafoods products collected from traditional fish market in Bali Province during 2023
    Putu Eka Sudaryatma, Putu Angga Wiradana, Imanuddin Razaq, Ni Luh Sunarsih, Aris Jatmiko, Anak Agung Ayu Putri Permatasari, Ni Kadek Yunita Sari, I Gede Widhiantara, I Made Gde Sudyadnyana Sandhika, I Wayan Rosiana
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    Wing Yui Ngan, Subramanya Rao, Aster Hei Yiu Fung, Olivier Habimana
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    Md. Abdullah Evna Hasan, Md Saiful Islam, Naeem Ahammed Ibrahim Fahim, Md. Tabeer Hossain Antor, Samia Salam, Rownak Jahan, Rony Ibne Masud, Zuhayr Bakhtiyar, Dilruba Akter Jany, Md. Liton Rana, Sadia Afrin Punom, Al Muksit Mohammad Taufiquer Rahman, Md.
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  • Food Safety Practices and Behavior Drivers in Traditional Food Markets in Ethiopia: Assessing the Potential for Consumer-Driven Interventions
    Ariel V. Garsow, Smret Hagos, Eric Djimeu, Carrel Fokou, Haley Swartz, Genet Gebremedhin, Bisaku Chacha, Elisabetta Lambertini
    International Journal of Environmental Research and Public Health.2025; 22(11): 1645.     CrossRef
COVID-19: Original Article
Associations of racial and ethnic discrimination with adverse changes in exercise and screen time during the COVID-19 pandemic in the United States
Tong Xia, Gilbert C. Gee, Jian Li, Xinyue Liu, Jin Dai, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su, Liwei Chen
Epidemiol Health. 2023;45:e2023013.   Published online January 28, 2023
DOI: https://doi.org/10.4178/epih.e2023013
  • 19,065 View
  • 120 Download
  • 4 Web of Science
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
During the coronavirus disease 2019 (COVID-19) pandemic, a growing prevalence of racial and ethnic discrimination occurred when many Americans struggled to maintain healthy lifestyles. This study investigated the associations of racial and ethnic discrimination with changes in exercise and screen time during the pandemic in the United States.
METHODS
We included 2,613 adults who self-identified as non-Hispanic White, non-Hispanic Black, non-Hispanic Asian, or Hispanic from the Health, Ethnicity, and Pandemic study, a cross-sectional survey conducted among a nationally representative sample of United States adults between October and November 2020. We assessed self-reported racial and ethnic discrimination by measuring COVID-19-related racial and ethnic bias and examined its associations with changes in exercise and screen time using multivariable logistic regression models. We analyzed data between September 2021 and March 2022.
RESULTS
COVID-19-related racial and ethnic bias was associated with decreased exercise time among non-Hispanic Asian (odds ratio [OR], 1.46; 95% confidence interval [CI], 1.13 to 1.89) and Hispanic people (OR, 1.91; 95% CI, 1.32 to 2.77), and with increased screen time among non-Hispanic Black people (OR, 1.94; 95% CI, 1.33 to 2.85), adjusting for age, sex, education, marital status, annual household income, insurance, and employment status.
CONCLUSIONS
Racial and ethnic discrimination may have adversely influenced exercise and screen time changes among racial and ethnic minorities during the COVID-19 pandemic in the United States. Further studies are needed to investigate the mechanisms through which racial and ethnic discrimination can impact lifestyles and to develop potential strategies to address racial and ethnic discrimination as a barrier to healthy lifestyles.
Summary
Key Message
In this study with a nationally representative sample of Americans, we found that racial discrimination during the COVID-19 pandemic was associated with undesired changes in exercise and screen time, particularly among minorities.

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  • Addressing Racism and Discrimination in the Design of Physical Activity Interventions for Black Women: Insights and Recommendations From an Academic and Community Partnership
    Rodney P. Joseph, LaTanya Mathis, Iyana Harris, Shawntele M. Howie-Carlson, Kanika Jones, Darlene Little, Dawn Augusta
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    Nilay S. Shah, Namratha R. Kandula, Yvonne Commodore-Mensah, Brittany N. Morey, Shivani A. Patel, Sally Wong, Eugene Yang, Stella Yi
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Original Articles
Multimorbidity patterns by health-related quality of life status in older adults: an association rules and network analysis utilizing the Korea National Health and Nutrition Examination Survey
Thi-Ngoc Tran, Sanghee Lee, Chang-Mo Oh, Hyunsoon Cho
Epidemiol Health. 2022;44:e2022113.   Published online November 29, 2022
DOI: https://doi.org/10.4178/epih.e2022113
  • 22,670 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Improved life expectancy has increased the prevalence of older adults living with multimorbidity which likely deteriorates their health-related quality of life (HRQoL). However, relatively little is known about patterns and the relationships of multimorbidity by HRQoL status in older adults.
METHODS
Individuals aged 65 or older from the Korea National Health and Nutrition Examination Survey V-VII (2010-2018) were analyzed. HRQoL was assessed by the EuroQoL-5 dimensions questionnaire and categorized as poor, normal, or good. The impact of multimorbidity on HRQoL was evaluated using logistic regression. The patterns and inter-relationships between multimorbidity, stratified by HRQoL groups, were analyzed using the association rules and network analysis approach.
RESULTS
Multimorbidity was significantly associated with poor HRQoL (3 or more diseases vs. none; adjusted odds ratio, 2.70; 95% confidence interval, 2.10 to 3.46). Hypertension, arthritis, hyperlipidemia, and diabetes were the most prevalent diseases across all HRQoL groups. Complex interrelationships of morbidities, higher prevalence, and node strengths in all diseases were observed in the poor HRQoL group, particularly for arthritis, depression, and stroke, compared to other groups (1.5-3.0 times higher, p<0.05 for all). Apart from hypertension, arthritis and hyperlipidemia had a higher prevalence and stronger connections with other diseases in females, whereas this was the case for diabetes and stroke in males with poor HRQoL.
CONCLUSIONS
Multimorbidity patterns formed complicatedly inter-correlated disease networks in the poor HRQoL group with differences according to sex. These findings enhance the understanding of multimorbidity connections and provide information on the healthcare needs of older adults, especially those with poor HRQoL.
Summary
Korean summary
기대 수명의 증가에 따라 고령인구에서 건강관련 삶의 질을 저하시킬 수 있는 복합질환의 유병률도 함께 증가하고 있다. 본 연구에서는 국민건강영양조사 자료를 이용하여 65세 이상 우리나라 고령인구에서 건강관련 삶의 질 (HRQoL)에 따른 복합만성질환 패턴을 분석하였다. 복합만성질환은 건강관련 삶의 질 저하와 통계적으로 유의하게 연관되어 있으며, 연관성 및 네크워크 분석 결과 건강관련 삶의 질이 낮을수록 복합질환의 패턴이 복잡한 것으로 나타났다. 전체적으로 고혈압, 관절염, 고지혈증, 당뇨병이 가장 높은 발생률을 보였다. 건강관련 삶의 질이 낮은 그룹에서는 관절염, 우울증, 뇌졸중 등의 질병이 높은 발생률과 상호관련성을 보였으며, 이는 성별에 따라 차이가 있었다. 연구 결과는 고령자, 특히 건강관련 삶의 질이 낮은 노인의 의료 서비스 요구에 대해 정보를 제공해 줄 수 있을 것이다,
Key Message
Network analysis of older adults (65 or older) in Korea showed that hypertension, arthritis, hyperlipidemia, and diabetes were the most common multimorbidity regardless of HRQoL status. However, as HRQoL deteriorated, multimorbidity patterns formed complicatedly inter-correlated disease networks; the prevalence and the node strength of arthritis, depression, and stroke increased considerably and be diversified by sex.

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    Huali Xiong, Fengxun Ma
    Medicine.2026; 105(3): e46805.     CrossRef
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    Yezhou Liu, Baibing Mi, Leilei Pei, Shaonong Dang, Hong Yan, Chao Li
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Health-adjusted life expectancy according to lifestyle classified by the Yonsei Lifestyle Profile-BREF
Sanghun Nam, Kang-Hyun Park, Ji-Hyuk Park, Ickpyo Hong
Epidemiol Health. 2022;44:e2022095.   Published online October 28, 2022
DOI: https://doi.org/10.4178/epih.e2022095
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to investigate health-adjusted life expectancy (HALE) by demographic characteristics (sex, educational achievement, and residential area) according to the lifestyle classifications of the Yonsei Lifestyle Profile-BREF (YLP-BREF).
METHODS
This study included 569 participants aged 55 years or older living in Korea. The YLP-BREF domains were physical activity, activity participation, and nutrition.
RESULTS
Females had a longer HALE (mean±standard deviation, 8.90±5.06 years) in the physical activity domain, while males had a longer HALE in the nutrition domain (9.44±5.91 years). People living in rural areas had longer HALE in physical activity (12.02±5.60 years), activity participation (8.58±4.21 years), and nutrition (11.33±6.43 years). There were no significant differences according to sex or residential area. High school graduates showed the longest HALE (physical activity: 10.38± 6.89; activity participation: 7.64±4.29; nutrition: 9.59±6.40 years). There was a significant difference in educational achievement.
CONCLUSIONS
As people age, the demand for a healthy lifestyle increases. This study attempted to calculate HALE by demographic characteristics according to lifestyle. The results of this study will help inform future research directions for providing a healthy lifestyle.
Summary
Korean summary
본 연구는 Yonsei Lifestyle Profile-BREF(YLP-BREF)의 라이프스타일 분류에 따른 인구통계학적 특성(성별, 주거지역, 학력)에 따른 건강조정수명(Health-Adjusted Life Expectancy; HALE)을 알아보고자 하였다. 본 연구에서 사용한 자료는 한국에 거주하는 55세 이상의 569명이 포함되었으며, YLP-BREF는 신체활동, 활동참여, 영양으로 총 세 영역으로 구성되어 있다. 본 연구 결과, 성별에 따른 건강조정수명은 영양에서 9.44세로 남성이 가장 높았으며, 거주지역은 따른 건강조정수명은 신체활동 영역에서 농촌이 12.02세로 가장높았고, 학력에 따른 건강조정수명은 신체활동 영역에서 고등학교 졸업자가 10.38세로 가장 높았다. 본 연구 결과는 건강한 라이프스타일을 인구통계학적 특성에 따라 제공하기 위한 향후 연구 방향을 제시하는 데 도움이 될 것으로 사료된다.
Key Message
This study investigated Health-Adjusted Life Expectancy (HALE) according to demographic characteristics (sex, residence, educational achievement) according to lifestyle classification of Yonsei Lifestyle Profile-BREF. As a result of this study, the HALE by gender was the highest in nutrition at 9.44 years, and the HALE by residential area was the highest in physical activity at 12.02 years in rural areas, and the HALE by education was in physical activity. , high school graduates had the highest age at 10.38. The results of this study are considered to be helpful in suggesting future research directions for providing a healthy lifestyle.
Application of a joint latent space item response model to clustering stressful life events and the Beck Depression Inventory-II: results from Korean epidemiological survey data
Hyun Joo Kim, Ye Jin Jeon, Hyeon Chang Kim, Ick Hoon Jin, Sun Jae Jung
Epidemiol Health. 2022;44:e2022093.   Published online October 24, 2022
DOI: https://doi.org/10.4178/epih.e2022093
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
According to previous findings, stressful life events (SLEs) and their subtypes are associated with depressive symptoms. However, few studies have explored potential models for these events and incidental symptoms of depression.
METHODS
Participants (3,966 men; 5,709 women) were recruited from the Cardiovascular and Metabolic Diseases Etiology Research Center cohort. SLEs were measured using a 47-item Life Experiences Survey (LES) with a standardized protocol. Depressive symptoms were assessed using the Beck Depression Inventory-II (BDI-II). Joint latent space item response models were applied by gender and age group (<50 vs. ≥50 years old).
RESULTS
Among the LES items, death or illness of close relatives, legal problems, sexual difficulties, family relationships, and social relationships shared latent positions with major depressive symptoms regardless of gender or age. We also observed a gender-specific domain: occupational and family-related items.
CONCLUSIONS
By projecting LES and BDI-II data onto the same interaction map for each subgroup, we could specify the associations between specific LES items and depressive symptoms.
Summary
Korean summary
- 본 연구는 성별, 연령에 따른 생활스트레스 항목과 Beck Depression Inventory-II (BDI-II) 로 측정한 우울증상 사이의 연관성을 Joint Latent space item response model (LSIRM) 방법을 사용하여 탐색하고자 하였다. - 한국 성인 인구집단 (3,966 남성; 5,709 여성)을 대상으로 연구를 수행한 결과, 생활스트레스 항목 중 가족 혹은 가까운 주변인의 죽음 혹은 질환, 법적인 문제, 성적 어려움, 가족 혹은 사회적 관계는 성별, 연령에 무관하게 우울 증상과 연관성이 있었으며, 직업, 일부 가족 관련 항목에서 성별 특이적인 연관성을 관찰하였다.
Key Message
- In this study, we used a joint latent space item response model (LSIRM) to project stressful life events and depressive symptoms as measured by the Beck Depression Inventory-II (BDI-II) onto an interaction map, which represents the interaction of BDI-II items and underlying traits with each SLE, while accounting for heterogeneity by sex and age group. - Among the LES items, death/illness of close relatives, legal problems, sexual difficulties, family relationships, and social relationships shared latent positions with major depressive symptoms regardless of sex or age group. But, in occupational and family-related items, sex-specific associations were observed.

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Association of the inflammatory balance of diet and lifestyle with colorectal cancer among Korean adults: a case-control study
Shinyoung Jun, Jeonghee Lee, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin, Jeongseon Kim
Epidemiol Health. 2022;44:e2022084.   Published online September 30, 2022
DOI: https://doi.org/10.4178/epih.e2022084
  • 17,672 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Dietary and lifestyle exposures may affect the risk of colorectal cancer (CRC) by promoting chronic inflammation. Therefore, we assessed the separate and joint associations of dietary and lifestyle inflammation scores (DIS and LIS, respectively) with CRC.
METHODS
Data from 919 pathologically confirmed CRC cases and 1,846 age- and sex-matched controls recruited at the National Cancer Center Korea were analyzed. We calculated the DIS and LIS, which characterize the collective contributions of 19 dietary and 4 lifestyle factors, respectively, to systemic inflammation by applying weights based on high-sensitivity C-reactive protein. A higher score represented a higher balance of pro- to anti-inflammatory exposures. Unconditional logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for CRC risk compared across the DIS and LIS tertile categories, with the lowest tertile as the reference group.
RESULTS
The highest DIS tertile had significantly increased odds of having CRC (OR, 2.65; 95% CI, 2.10 to 3.36), and the odds increased with increasing DIS. The highest LIS tertile group had 1.28-fold higher odds of having CRC (95% CI, 1.03 to 1.58). In the cross-classification analysis, the odds of having CRC increased as the DIS and LIS jointly increased until the DIS reached the highest tertile, where the risk was very high (3-fold or more) regardless of the LIS.
CONCLUSIONS
In conclusion, a higher balance of pro-inflammatory relative to anti-inflammatory dietary and lifestyle factors, especially dietary factors, was associated with higher CRC risk among Korean adults.
Summary
Korean summary
본 연구는 국립암센터에서 수집한 대장암 환자-대조군 데이터를 활용하여, 새롭게 개발된 식이 염증 지수(Dietary Inflammation Score, DIS) 및 생활습관 염증 지수(Lifestyle Inflammation Score, LIS)와 대장암 발생 위험 간의 연관성을 탐색하였다. 분석 결과, 식이 염증 지수 혹은 생활습관 염증 지수가 높은 집단에서 대장암 위험이 더 높아, 식이와 생활습관이 체내 염증 수준을 높여 대장암 발생 위험을 높일 가능성이 제기되었다
Key Message
Dietary inflammation score (DIS) and lifestyle inflammation score (LIS) quantify the collective effect of dietary and lifestyle factors, respectively, on systemic inflammation. In this case-control study, we assessed the associations of DIS and LIS with colorectal cancer risk among Korean adults. Our results suggest that a higher balance of pro-to anti-inflammatory dietary and lifestyle factors may be associated with higher risk for colorectal cancer. The findings from our study support that reducing inflammation through dietary or lifestyle changes could potentially reduce the risk for colorectal cancer.

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  • Performance of cohort-adapted dietary and lifestyle inflammation scores among Hispanic adults
    Lisa C. Merrill, Sabrina E. Noel, Rafael López Martínez, Josiemer Mattei, Natalia Palacios, Yan Wang, Katherine L. Tucker, Kelsey M. Mangano
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    Kyeong Min Han, Ho Suk Kang, Joo-Hee Kim, Hyo Geun Choi, Dae Myoung Yoo, Nan Young Kim, Ha Young Park, Mi Jung Kwon
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    Palaniyandi Muthukutty, Hyun Young Woo, So Young Yoo
    Vaccines.2025; 13(7): 689.     CrossRef
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    Jiali Zheng, Longgang Zhao, Jingwen Dong, Edward Giovannucci
    Cancer Epidemiology, Biomarkers & Prevention.2025; 34(10): 1810.     CrossRef
  • The association of diet-dependent acid load with colorectal cancer risk: a case–control study in Korea
    Tao Thi Tran, Madhawa Gunathilake, Jeonghee Lee, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin, Jeongseon Kim
    British Journal of Nutrition.2024; 131(2): 333.     CrossRef
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    Duo Feng, Di Han, Mengjie Li, Hu Li, Na Li, Tianxin Liu, Jing Wang
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    Mi Jung Kwon, Kyeong Min Han, Joo-Hee Kim, Ji Hee Kim, Min-Jeong Kim, Nan Young Kim, Hyo Geun Choi, Ho Suk Kang
    Cancers.2023; 15(23): 5602.     CrossRef
  • Dietary intake and cancer incidence in Korean adults: a systematic review and meta-analysis of observational studies
    Ji Hyun Kim, Shinyoung Jun, Jeongseon Kim
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Inequitable distribution of excess mortality during the COVID-19 pandemic in Korea, 2020
Jin-Hwan Kim, Saerom Kim, Eunhye Park, Chang-yup Kim
Epidemiol Health. 2022;44:e2022081.   Published online September 26, 2022
DOI: https://doi.org/10.4178/epih.e2022081
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AbstractAbstract PDFSupplementary Material
Abstract
OBJECTIVES
This study analyzed inequities in excess mortality according to region and socioeconomic position to explain the distribution of excess mortality in Korea in 2020.
METHODS
We acquired weekly all-cause mortality data from January 2015 to December 2020 from (1) the National Health Insurance Database and (2) Vital Statistics. Excess mortality for 2020 was calculated by comparing the weekly observed and expected deaths from the same period (2015-2019) using quasi-Poisson regression.
RESULTS
An inequitable distribution of excess mortality was identified. The estimated excess mortality in Korea was -29,112 (95% confidence interval, -29,832 to -28,391), corresponding to -55 per 100,000, and the ratio of observed deaths to expected deaths was 0.91. Negative excess mortality was observed except for females in the 0-14 age group. Male Medical Aid beneficiaries showed positive excess mortality, while non-disabled and disabled groups showed similar negative values. When the standardized mortality ratio was calculated for the top 10 causes of death, deaths from Alzheimer’s disease and septicemia increased, whereas those from diabetes mellitus and cerebrovascular disease decreased. The decrease in mortality was primarily concentrated in older adults, while the mortality of young females increased due to increased intentional self-harm.
CONCLUSIONS
This study adds essential evidence regarding the overall performance of Korea. The observed inequalities according to various socioeconomic variables indicate that the results of strict measures to control coronavirus disease 2019 were not distributed equitably. Efforts should be made to properly evaluate the current and future problems related to the pandemic.
Summary

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    Ganan Devanathan, Paul LC Chua, Shuhei Nomura, Chris Fook Sheng Ng, Nasif Hossain, Akifumi Eguchi, Masahiro Hashizume
    BMJ Public Health.2025; 3(1): e002357.     CrossRef
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    Jin-Hwan Kim, Saerom Kim
    Health Policy.2025; 159: 105375.     CrossRef
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    Jiwoo Ha, Chang‐yup Kim
    Sociology of Health & Illness.2025;[Epub]     CrossRef
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    Seohwa Park, Jungmin Seo
    Cambridge Review of International Affairs.2025; 38(5): 654.     CrossRef
  • The Predestined Failure of the Market Mechanism in Ensuring Health for all in Times of a Pandemic: The Case of the Republic of Korea
    Jin-Hwan Kim
    International Journal of Social Determinants of Health and Health Services.2025; 55(4): 465.     CrossRef
  • Can resident registration expiration statistics due to death be used for near-real-time mortality tracking? A validation study using 2023 data from Korea
    Jin-Hwan Kim
    Epidemiology and Health.2025; 47: e2025042.     CrossRef
  • Excess mortality and healthcare costs during the COVID-19 pandemic among patients with ten major chronic diseases in South korea: a nationwide analysis
    Jihun Song, Hye Jun Kim, Seogsong Jeong, Sun Jae Park, Hyun-Young Shin, Eun-kyeong Jeong, Jaehun Jung, Geehyuk Kim, Sang Min Park
    BMC Infectious Diseases.2025;[Epub]     CrossRef
  • Universal health coverage saves more lives among severely ill COVID-19 patients: A difference-in-differences analysis of individual patient data in South Korea
    Daseul Moon, Jeangeun Jeon, Jieun Park, Min-Hyeok Choi, Myoung-Hee Kim, Hongjo Choi
    Health Research Policy and Systems.2024;[Epub]     CrossRef
  • Excess Deaths in Korea During the COVID-19 Pandemic: 2020-2022
    So-Jin Im, Ji-Yeon Shin, Duk-Hee Lee
    Journal of Preventive Medicine and Public Health.2024; 57(5): 480.     CrossRef
  • Did the socioeconomic inequalities in avoidable and unavoidable mortality worsen during the first year of the COVID-19 pandemic in Korea?
    Rora Oh, Myoung-Hee Kim, Juyeon Lee, Rangkyoung Ha, Jungwook Kim
    Epidemiology and Health.2023; 45: e2023072.     CrossRef
The associations of the national health and productivity management program with corporate profits in Japan
Yuichiro Yano, Hiroshi Kanegae, Koichi Node, Atsushi Mizuno, Akira Nishiyama, Hiromi Rakugi, Hiroshi Itoh, Kaori Kitaoka, Naoki Kashihara, Fumiaki Ikeno, Ichiro Tsuji, Kunio Okada
Epidemiol Health. 2022;44:e2022080.   Published online September 23, 2022
DOI: https://doi.org/10.4178/epih.e2022080
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Using a dataset from a survey on national health and productivity management, we identified health and productivity factors associated with organizational profitability.
METHODS
The Ministry of Economy, Trade and Industry conducted an annual survey on Health and Productivity Management between 2014 and 2021. We assessed the associations of organizational health and productivity management using survey questions collected in 2017 and 2018, with the rate of change in profits from 2017 and 2018 to 2020. We identified factors associated with organizational profitability using eXtreme Gradient Boosting, and calculated SHapley Additive exPlanation (SHAP) values for each factor.
RESULTS
Among 1,593 companies (n= 4,359,834 employees), the mean age of employees at baseline was 40.3 years and the proportion of women was 25.8%. A confusion matrix for evaluating model performance had an accuracy of 0.997, precision of 0.993, recall of 0.997, and area under the precision-recall curve of 0.999. The most important factors related to an increase in corporate profits were the percentage of current smokers (SHAP value, 0.121), per-employee cost of health services (0.084) and medical services (0.050); the percentage of full-time employees working in sales departments (0.074) and distribution or customer service departments (0.054); the percentage of employees who slept well (0.055); and the percentage of employees within a company who regularly exercised (0.043).
CONCLUSIONS
Employees’ lifestyle-related health risk factors and organizations’ management systems were associated with organizational profitability. Lifestyle medicine professionals may demonstrate a significant return on investment by creating a healthier and more productive workforce.
Summary
Key Message
Lifestyle medicine professionals may demonstrate a significant return on investment by creating a healthier and more productive workforce

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  • Key Performance Indicators in Workplace Health Promotion
    Kosuke Sakai, Shoko Nakazawa, Yuko Furuya, Kota Fukai, Kei Sano, Masayuki Tatemichi
    Journal of Occupational & Environmental Medicine.2026; 68(1): e61.     CrossRef
  • Incorporating Lifestyle Medicine Into Occupational Medicine Practice
    Pamela A. Hymel, Gregg M. Stave, Wayne N. Burton, Alyssa B. Schultz, Nathan Jones, Jeffrey Liva, Richard D. Price, Ron Loeppke, Ronald Stout, Kenji Saito
    Journal of Occupational & Environmental Medicine.2025; 67(1): e72.     CrossRef
  • Effect of perceived workplace health support on absenteeism and presenteeism among Japanese workers: a prospective cohort study
    Kazushirou Kurogi, Kazunori Ikegami, Hajime Ando, Akira Ogami
    Journal of Occupational Health.2025;[Epub]     CrossRef
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    Gahao Chen, Ziwei Yang, Benjamin M. Liu
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  • Tuning out tension: influence of music on stress level among project management practitioners
    Ye Fu, Xiaohua Jin, Srinath Perera, Bashir Tijani, Prakriti Pokhrel
    Engineering, Construction and Architectural Management.2025; : 1.     CrossRef
  • The association between employee lifestyles and the rates of mental health-related absenteeism and turnover in Japanese companies
    Atsuya Fujimoto, Hiroshi Kanegae, Kaori Kitaoka, Mizuki Ohashi, Kunio Okada, Koichi Node, Kenkichi Takase, Hiroshi Fukuda, Tomoyuki Miyazaki, Yuichiro Yano
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  • Role and Value of the Corporate Medical Director
    Gregg M. Stave, Wayne N. Burton, Richard J.L. Heron, T. Warner Hudson, J. Brent Pawlecki, David Roomes, Martin J. Sepulveda, Michael Rendel, Pamela A. Hymel
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Prediction of cancer survivors’ mortality risk in Korea: a 25-year nationwide prospective cohort study
Yeun Soo Yang, Heejin Kimm, Keum Ji Jung, Seulji Moon, Sunmi Lee, Sun Ha Jee
Epidemiol Health. 2022;44:e2022075.   Published online September 13, 2022
DOI: https://doi.org/10.4178/epih.e2022075
  • 20,867 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to investigate the factors affecting cancer survival and develop a mortality prediction model for Korean cancer survivors. Our study identified lifestyle and mortality risk factors and attempted to determine whether health-promoting lifestyles affect mortality.
METHODS
Among the 1,637,287 participants in the Korean Cancer Prevention Study (KCPS) cohort, 200,834 cancer survivors who were alive after cancer diagnosis were analyzed. Discrimination and calibration for predicting the 10-year mortality risk were evaluated. A prediction model was derived using the Cox model coefficients, mean risk factor values, and mean mortality from the cancer survivors in the KCPS cohort.
RESULTS
During the 21.6-year follow-up, the all-cause mortality rates of cancer survivors were 57.2% and 39.4% in men and women, respectively. Men, older age, current smoking, and a history of diabetes were high-risk factors for mortality, while exercise habits and a family history of cancer were associated with reduced risk. The prediction model discrimination in the validation dataset for both KCPS all-cause mortality and KCPS cancer mortality was shown by C-statistics of 0.69 and 0.68, respectively. Based on the constructed prediction models, when we modified exercise status and smoking status, as modifiable factors, the cancer survivors’ risk of mortality decreased linearly.
CONCLUSIONS
A mortality prediction model for cancer survivors was developed that may be helpful in supporting a healthy life. Lifestyle modifications in cancer survivors may affect their risk of mortality in the future.
Summary
Korean summary
현재 암 생존자의 사망 위험을 평가하는 데 유용한 한국형 암 생존자 사망률 예측 모델은 없습니다. 본 연구에서는 고령, 남성, 현재 흡연, 당뇨병 병력을 포함한 생활양식 요인이 사망의 고위험 요인인 반면, 운동 습관 및 암의 가족력은 사망 위험을 감소시키는 것으로 나타났습니다. 현재 흡연과 운동 습관은 사망 위험에 영향을 미치는 수정 가능한 두 가지 요소로써, 이러한 생활습관 요인으로 구성된 예측모형은 생활습관 교정을 통해 우리나라 암 생존자의 사망률을 낮출 수 있음을 시사합니다.
Key Message
Currently, there is no Korean mortality prediction model for cancer survivors that would be useful in evaluating their risk of mortality. The present study showed that lifestyle factors, including older age, male sex, current smoking, and history of diabetes were high-risk factors for mortality, while exercise habits and a family history of cancer reduced the risk of mortality. Current smoking and exercise habits are the two modifiable factors that affected the risk of mortality. The prediction model comprising these lifestyle factors implies that the risk of mortality of cancer survivors in Korea can be reduced through lifestyle modification.

Citations

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  • A comparative study of health behaviors in adult male cancer survivors and the general male population in Korea: from the Korea national health and nutrition examination survey VII-VIII (2016–2021)
    Hyein Jung, Yoonjoo Choi, Byungmi Kim
    Supportive Care in Cancer.2025;[Epub]     CrossRef
  • Sex Disparity in Cancer and Non-cancer Mortality among Korean Cancer Survivors
    Ansun Jeong, Soyeoun Kim, Somin Jeon, Boyoung Park
    Journal of Cancer Prevention.2025; 30(4): 196.     CrossRef
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    Jae-Min Park, Hye Yeon Koo, Jae-ryun Lee, Hyejin Lee, Jin Yong Lee
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Weight maintenance and gain were significantly associated with lower risk of all-cause and cancer-related mortality in Korean adults who were newly diagnosed with cancer based on the Korean NHIS-HEALS cohort
    Yong-June Kim, Seung Park, Won Tae Kim, Yoon-Jong Bae, Yonghwan Kim, Hee-Taik Kang
    Medicine.2023; 102(47): e36184.     CrossRef
The medium-term consequences of a COVID-19 lockdown on lifestyle among Spanish older people with hypertension, pulmonary disease, cardiovascular disease, musculoskeletal disease, depression, and cancer
Irene Rodríguez-Gómez, Coral Sánchez-Martín, Francisco J. García-García, Esther García-Esquinas, Marta Miret, Germán Vicente-Rodriguez, Narcís Gusi, Asier Mañas, José A. Carnicero, Marcela Gonzalez-Gross, José L. Ayuso-Mateos, Fernando Rodríguez-Artalejo, Leocadio Rodríguez-Mañas, Ignacio Ara
Epidemiol Health. 2022;44:e2022026.   Published online February 21, 2022
DOI: https://doi.org/10.4178/epih.e2022026
  • 22,228 View
  • 378 Download
  • 3 Web of Science
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study investigated the associations of chronic diseases with changes in lifestyle and health behaviours in older people following the coronavirus disease 2019 (COVID-19) lockdown in Spain and compared the differences in changes over time.
METHODS
1,092 participants (80.3±5.6 years; 66.5% female) from 2 Spanish cohorts were included. Telephone-based questionnaires were conducted to evaluate lifestyle and health risk behaviours at the end of lockdown and 7 months post-lockdown. Participants were classified as having physician-diagnosed chronic diseases based on self-reported data. Cox proportional models adjusted for major confounders were used.
RESULTS
Compared to those without the corresponding chronic diseases, older people with hypertension were less likely to report increased alcohol consumption (hazard ratio [HR], 0.73; 95% confidence interval [CI], 0.55 to 0.99). Pulmonary diseases were associated with lower risks of increased sedentary time (HR, 0.58; 95% CI, 0.39 to 0.86) and worsened sleep quality (HR, 0.56; 95% CI, 0.36 to 0.87), while cardiovascular diseases were associated with a lower risk of decreased sedentary time (HR, 0.58; 95% CI, 0.38 to 0.88). Depression was linked to a higher likelihood of improved diet quality (HR, 1.53; 95% CI, 1.00 to 2.36). Cancer pacients were less likely to have worsened sleep quality (HR, 0.44; 95% CI, 0.22 to 0.89) but more likely to have reduced their frequency of social contact (HR, 2.05; 95% CI, 1.05 to 3.99).
CONCLUSIONS
Older people with chronic diseases showed beneficial changes in lifestyle and health risk behaviours after the COVID-19 lockdown. In particular, older people with hypertension, pulmonary disease, and cancer tended to make beneficial lifestyle and health behaviour changes. However, older people with cardiovascular disease and depression engaged in more health risk behaviours.
Summary
Key Message
Although the majority of older people with chronic diseases showed beneficial changes in lifestyle and health risk behaviors after the COVID-19 lockdown, public health interventions should be developed to prevent the dangerous long-term effects that COVID-19 pandemic-type situations may have on the health of older people, with a particular focus on older people with CVD and depression that seem to have experienced more health risk behaviors during the COVID-19 pandemic than older people with other chronic diseases.

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  • Global burden of sleep disturbances among older adults and the disparities by geographical regions and pandemic periods
    Min Du, Min Liu, Yaping Wang, Chenyuan Qin, Jue Liu
    SSM - Population Health.2024; 25: 101588.     CrossRef
  • More Adult Women than Men at High Cardiometabolic Risk Reported Worse Lifestyles and Self-Reported Health Status in the COVID-19 Lockdown
    Alejandro Oncina-Cánovas, Laura Compañ-Gabucio, Jesús Vioque, Miguel Ruiz-Canela, Dolores Corella, Jordi Salas-Salvadó, Montserrat Fitó, Alfredo Martínez, Ángel M. Alonso-Gómez, Julia Wärnberg, Dora Romaguera, José López-Miranda, Ramón Estruch, Francisco
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  • Nut Consumption and Depression: Cross-Sectional and Longitudinal Analyses in Two Cohorts of Older Adults
    R. Fernández-Rodríguez, R. Ortolá, Vicente Martínez-Vizcaíno, B. Bizzozero-Peroni, F. Rodríguez-Artalejo, E. García-Esquinas, E. López-García, A.E. Mesas
    The Journal of nutrition, health and aging.2023; 27(6): 448.     CrossRef
Association of social network size and composition with physical activity in Korean middle-aged adults
Moon Su Kwak, So Mi Jemma Cho, Jee-Seon Shim, Dae Jung Kim, Yoosik Youm, Hyeon Chang Kim
Epidemiol Health. 2020;42:e2020070.   Published online November 25, 2020
DOI: https://doi.org/10.4178/epih.e2020070
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Physical activity (PA) is an established protective factor for many chronic diseases. Numerous studies have established positive relationships between social networks and PA. Accordingly, this study examined the relationship between social network structures (specifically the network size and the number and proportion of same-sex alters) and self-reported PA in Korean middle-age adults, where the term “alter” refers to a respondent’s social network members.
METHODS
We analyzed 8,092 participants of the Cardiovascular and Metabolic Diseases Etiology Research Center cohort. We assessed the association between each network structure variable and PA level using a linear regression model. Then, we employed logistic regression to evaluate associations between social network structure and adherence to guideline-recommended exercise levels. Socio-demographic factors and health status measures were used as covariates.
RESULTS
In both sexes, the social network size and proportion of same-sex network members showed positive relationships with total and moderate-to-vigorous PA. Notably, female participants with a greater number of kin were more likely to satisfy the recommended amount of total PA.
CONCLUSIONS
These findings suggest that large scale, same-sex intervention programs can help to achieve recommended PA regimens.
Summary
Korean summary
이 연구는 30-64세 중년의 한국인 8,092(남자 2,805, 여자 5,207)명에서 사회연결망 특성과 신체활동량의 관련성을 평가했다. 남녀 모두에서 사회연결망의 크기가 클수록, 연결망내 동성인 사람의 비중이 높을수록 신체활동량이 많았다. 사회연결망 크기와 연결망내 동성인 사람의 비중은 권장 신체활동량을 충족률과도 양의 관련성을 보였다. 반면, 연결망내 친족의 비중이 높은 경우는 오히려 권장신체활동량을 충족할 가능성이 낮았다.
The patterns of lifestyle, metabolic status, and obesity among hypertensive Korean patients: a latent class analysis
Suyoung Kim, Seon Cho, Eun-Hee Nah
Epidemiol Health. 2020;42:e2020061.   Published online August 31, 2020
DOI: https://doi.org/10.4178/epih.e2020061
  • 21,855 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to identify latent classes in hypertensive patients based on the clustering of factors including lifestyle risk factors, metabolic risk factors, and obesity in each sex.
METHODS
This cross-sectional study included 102,780 male and 103,710 female hypertensive patients who underwent health check-ups at 16 centers in Korea, in 2018. A latent class analysis approach was used to identify subgroups of hypertensive patients. Multinomial logistic regression was performed to examine the association between latent classes and comorbidities of hypertension.
RESULTS
A four-class model provided the best fit for each sex. The following latent classes were identified: Class I (male: 16.9%, female: 1.7%; high risk of lifestyle behaviors [HB] with metabolic disorders and obesity [MO]), Class II (male: 32.4%, female: 47.1%; low risk of lifestyle behaviors [LB] with MO), Class III (male: 15.3%, female: 1.8%; HB with metabolic disorders and normal weight [MNW]), Class IV (male: 35.5%, female: 49.4%; LB with MNW). Lifestyle patterns in the latent classes were classified as high-risk or low-risk according to smoking and high-risk drinking among male, and presented complex patterns including physical inactivity alone or in combination with other factors, among female. Stage 2 hypertensive or diabetic individuals were likely to belong to classes including obesity (HB-MO, LB-MO) in both sexes, and additionally belonged to the HB-MNW class in male.
CONCLUSIONS
Metabolic disorders were included in all latent classes, with or without lifestyle risk factors and obesity. Hypertensive females need to manage obesity, and hypertensive males need to manage lifestyle risk factors and obesity. Sex-specific lifestyle behaviors are important for controlling hypertension.
Summary
Korean summary
고혈압 환자에서 이질적인 집단을 확인하기 위해, 생활습관, 대사이상 및 비만에 기반한 잠재계층분석을 실시한 결과, 각 성별에서 4개 계층으로 분류되었다. 모든 계층에는 대사이상 상태가 포함되었으며, 고위험 생활습관과 비만(HB-MO), 저위험 생활습관과 비만(LB-MO), 고위험 생활습관과 정상체중(HB-MNW), 저위험 생활습관과 정상체중(LB-MNW)으로 유형화하였다. 생활습관 및 비만 여부와 상관없이 모든 잠재계층에 대사이상 상태가 포함된 점으로 고혈압과 대사상태의 긴밀한 관련성을 확인하였으며, 성별에 따라 이질적인 생활습관 패턴(여성에서는 비만 관리와 남성에서는 비만과 생활습관 개선을 강조)을 확인하였다.

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  • The mediating effect of the Korean Healthy Eating Index on the relationship between lifestyle patterns and metabolic syndrome in middle-aged Koreans: data from the 2019–2021 Korea National Health and Nutrition Examination Survey
    Sori On, Woori Na, Cheongmin Sohn
    Nutrition Research and Practice.2025; 19(1): 96.     CrossRef
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    I. L. Nikitina, N. I. Vtornikova, I. A. Kelmanson
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  • Linking health lifestyle classes to blue-collar workers’ participation in worksite health promotion programs in freight transport: a latent class analysis
    Marc A. W. Damen, Sarah I. Detaille, Luuk P. van Iperen, Josephine A. Engels, Annet H. De Lange
    International Archives of Occupational and Environmental Health.2025; 98(9-10): 883.     CrossRef
  • Patterns of unhealthy behaviours during adolescence and subsequent anxiety and depression in adulthood: a prospective register linkage study of the HUNT survey and health registries
    Annette Løvheim Kleppang, Mario Vianna Vettore, Ingeborg Hartz, Siri Håvås Haugland, Tonje Holte Stea
    International Journal of Behavioral Nutrition and Physical Activity.2023;[Epub]     CrossRef
  • Factors and at-risk group associated with hypertension self-management patterns among people with physical disabilities: a latent class analysis
    Hye Jin Nam, Ju Young Yoon
    BMC Public Health.2022;[Epub]     CrossRef
  • Analysis of Fruit Consumption and the Korean Healthy Eating Index of Adults Using the 2018 Korea National Health and Nutrition Examination Survey
    Sun A Choi, Sung Suk Chung, Jeong Ok Rho
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Factors associated with health-related quality of life in a working population in Singapore
Dhiya Mahirah, Charlotte Sauter, Thuan-Quoc Thach, Gerard Dunleavy, Nuraini Nazeha, George I. Christopoulos, Chee Kiong Soh, Josip Car
Epidemiol Health. 2020;42:e2020048.   Published online June 30, 2020
DOI: https://doi.org/10.4178/epih.e2020048
  • 26,776 View
  • 291 Download
  • 10 Web of Science
  • 9 Crossref
AbstractAbstract PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to evaluate the determinants of health-related quality of life (HRQoL) among workers in Singapore.
METHODS
We analysed data from a cross-sectional study of 464 participants from 4 companies in Singapore. Physical and mental components of HRQoL were assessed using the Short-Form 36 version 2.0 survey. A generalized linear model was used to determine factors associated with the physical component summary (PCS) and mental component summary (MCS) scores of HRQoL.
RESULTS
The overall mean PCS and MCS scores were mean±standard deviation 51.6±6.7 and 50.2±7.7, respectively. The scores for subscales ranged from 62.7±14.7 for vitality to 83.5±20.0 for role limitation due to emotional problems. Ethnicity, overweight/obesity, and years working at the company were significantly associated with physical HRQoL, and age and stress at work were significantly associated with mental HRQoL. Moreover, sleep quality was significantly associated with both physical and mental HRQoL.
CONCLUSIONS
These findings could help workplaces in planning strategies and initiatives for employees to maintain a worklife balance that encompasses their physical, emotional, and social well-being.
Summary

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    Krishnashree Achuthan, Sugandh Khobragade, Robin Kowalski, Raghu Raman
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    Myung-Ock Chae
    Research in Community and Public Health Nursing.2024; 35: 125.     CrossRef
  • The Impact of Teleworking on Women’s Work–Life Balance and Life Satisfaction: a Longitudinal Study from Singapore
    Jolene Tan, Jeremy Lim-Soh, Poh Lin Tan
    Applied Research in Quality of Life.2024; 19(5): 2595.     CrossRef
  • Lifestyle interventions improving health-related quality of life: A systematic review and meta-analysis of randomized control trials
    Sohrab Amiri, Nailah Mahmood, Sameeha Junaidi, Moien AB Khan
    Journal of Education and Health Promotion.2024;[Epub]     CrossRef
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    Svitlana Indyka, Nataliia Bielikova
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    Kok Hian Tan, Boon Leng Lim, Zann Foo, Joo Ying Tang, Mabel Sim, Phong Teck Lee, Kok Yong Fong
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    International Journal of Environmental Research and Public Health.2021; 18(23): 12835.     CrossRef
Lifestyle-related predictors affecting prediabetes and diabetes in 20-30-year-old young Korean adults
Kyong Sil Park, Seon Young Hwang
Epidemiol Health. 2020;42:e2020014.   Published online March 19, 2020
DOI: https://doi.org/10.4178/epih.e2020014
  • 25,858 View
  • 319 Download
  • 10 Web of Science
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
To investigate lifestyle-related predictors of prediabetes and diabetes in young adults aged 20–39 years using data from the 2014-2016 Korea National Health and Nutrition Examination Survey (KNHANES).
METHODS
This study is a cross-sectional, secondary analysis using the KNHANES data. Participants were classified into normal group (fasting plasma glucose [FPG] <100 mg/dL and/or hemoglobin A1c [HbA1c] <5.7%), prediabetes group (FPG 100-125 mg/dL and/or HbA1c 5.7-6.4%), and diabetes group (FPG ≥126 mg/dL and/or HbA1c ≥ 6.5%). The data were statistically analyzed using SPSS software.
RESULTS
Out of 4,190 participants, 27.7% of men and 16.3% of women were in the prediabetes group and 1.4% of men and 1.3% of women were in the diabetes group. Logistic regression confirmed that age and obesity are predictors of prediabetes and diabetes in both men and women. Additionally low physical activity and low education level are predictors of prediabetes in men and women, respectively (p<0.05).
CONCLUSIONS
This study has found that age and increased obesity are predictors of elevated blood glucose in young men and women in their 20s and 30s. A strategy to lower obesity by promoting physical activity in men in their 30s is essential to prevent metabolic syndrome and progression to prediabetes.
Summary
Korean summary
20-30대 젊은 성인 남성에서 당뇨전단계 27.7%, 당뇨 1.4%, 여성에서 당뇨전단계 16.4%, 당뇨 1.3%로 확인되었다. 당뇨전단계 및 당뇨의 이환을 예방하기 위해서 비만 관리가 필수적이며, 특히 교육수준이 낮은 젊은 여성과 신체활동이 낮은 30대의 남성에서 신체활동 증진을 통해 효율적으로 비만도를 낮추는 전략 마련이 필요함을 확인하였다.

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    Diabetes/Metabolism Research and Reviews.2026;[Epub]     CrossRef
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    Suhee Kim, Ju-Yeon Uhm
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Socio-demographic and lifestyle factors associated with multimorbidity in New Zealand
Nayyereh Aminisani, Christine Stephens, Joanne Allen, Fiona Alpass, Seyed Morteza Shamshirgaran
Epidemiol Health. 2020;42:e2020001.   Published online December 27, 2019
DOI: https://doi.org/10.4178/epih.e2020001
  • 26,549 View
  • 416 Download
  • 24 Web of Science
  • 20 Crossref
AbstractAbstract PDFSupplementary Material
Abstract
OBJECTIVES
The incidence of multimorbidity (MM) and its correlates among older adults remain poorly understood. This study aimed to examine the socio-demographic and lifestyle factors associated with MM in New Zealand.
METHODS
People aged 55-70 years were invited to participate in a population-based cohort study, the Health Work and Retirement Study, in 2006. Those who accepted the invitation and completed the baseline questionnaire were followed up on a biennial basis. Data on socio-demographic factors, health and lifestyle behaviours, and diagnoses of chronic diseases were obtained from baseline and 6 waves of follow-up. Generalised estimating equations (GEE) adjusted for both time-constant and time-varying factors were used to model factors associated with the onset of MM.
RESULTS
A total of 1,673 participants (with 0 or 1 chronic condition) contributed to an overall 8,616 person-years of observation. There were 590 new cases of MM over 10 years of follow-up, corresponding to an overall incidence of 68.5 per 1,000 person-years. The results of the age- and sex-adjusted GEE analysis showed that age, ethnicity, living alone, obesity, hypertension, and having 1 chronic condition at baseline were significant predictors of MM onset. Higher education, income, physical activity, and regular alcohol consumption were protective factors. In a fully adjusted model, marital status (odds ratio [OR], 1.18; 95% confidence interval [CI], 1.01 to 1.37; p=0.039), hypertension (OR, 1.23; 95% CI, 1.02 to 1.48; p=0.032) and having 1 chronic condition at baseline (OR, 2.92; 95% CI, 2.33 to 3.67; p<0.001) remained significant.
CONCLUSIONS
The higher incidence of MM among Māori people, socioeconomically disadvantaged groups, those with low physical activity, and obese individuals highlights the importance of targeted prevention strategies.
Summary

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Cohort Profile
Health Effects of Underground Workspaces cohort: study design and baseline characteristics
Gerard Dunleavy, Thirunavukkarasu Sathish, Nuraini Nazeha, Michael Soljak, Nanthini Visvalingam, Ram Bajpai, Hui Shan Yap, Adam C. Roberts, Thuan Quoc Thach, André Comiran Tonon, Chee Kiong Soh, Georgios Christopoulos, Kei Long Cheung, Hein de Vries, Josip Car
Epidemiol Health. 2019;41:e2019025.   Published online August 16, 2019
DOI: https://doi.org/10.4178/epih.e2019025
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AbstractAbstract PDFSupplementary Material
Abstract
The development of underground workspaces is a strategic effort towards healthy urban growth in cities with ever-increasing land scarcity. Despite the growth in underground workspaces, there is limited information regarding the impact of this environment on workers’ health. The Health Effects of Underground Workspaces (HEUW) study is a cohort study that was set up to examine the health effects of working in underground workspaces. In this paper, we describe the rationale for the study, study design, data collection, and baseline characteristics of participants. The HEUW study recruited 464 participants at baseline, of whom 424 (91.4%) were followed-up at 3 months and 334 (72.0%) at 12 months from baseline. We used standardized and validated questionnaires to collect information on socio-demographic and lifestyle characteristics, medical history, family history of chronic diseases, sleep quality, health-related quality of life, chronotype, psychological distress, occupational factors, and comfort levels with indoor environmental quality parameters. Clinical and anthropometric parameters including blood pressure, spirometry, height, weight, and waist and hip circumference were also measured. Biochemical tests of participants’ blood and urine samples were conducted to measure levels of glucose, lipids, and melatonin. We also conducted objective measurements of individuals’ workplace environment, assessing air quality, light intensity, temperature, thermal comfort, and bacterial and fungal counts. The findings this study will help to identify modifiable lifestyle and environmental parameters that are negatively affecting workers’ health. The findings may be used to guide the development of more health-promoting workspaces that attempt to negate any potential deleterious health effects from working in underground workspaces.
Summary

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    Thuan-Quoc Thach, Dhiya Mahirah, Gerard Dunleavy, Nuraini Nazeha, Yichi Zhang, Christina En Hui Tan, Adam Charles Roberts, George Christopoulos, Chee Kiong Soh, Josip Car
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  • A Multifactorial Approach to Sleep and Its Association with Health-Related Quality of Life in a Multiethnic Asian Working Population: A Cross-Sectional Analysis
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    International Journal of Environmental Research and Public Health.2019; 16(23): 4590.     CrossRef
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    Ushashree Divakar, Thirunavukkarasu Sathish, Michael Soljak, Ram Bajpai, Gerard Dunleavy, Nanthini Visvalingam, Nuraini Nazeha, Chee Kiong Soh, Georgios Christopoulos, Josip Car
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Review
Meta-analysis of the prevalence of depression among breast cancer survivors in Iran: an urgent need for community supportive care programs
Hassan Ahmadi Gharaei, Mostafa Dianatinasab, Seyyed Mostafa Kouhestani, Mohammad Fararouei, Hossein Moameri, Reza Pakzad, Reza Ghaiasvand
Epidemiol Health. 2019;41:e2019030.   Published online July 4, 2019
DOI: https://doi.org/10.4178/epih.e2019030
  • 27,679 View
  • 309 Download
  • 18 Web of Science
  • 22 Crossref
AbstractAbstract PDFSupplementary Material
Abstract
OBJECTIVES
Depression, which is the most common comorbidity in breast cancer (BC) patients, has adverse effects on patients’ quality of life, disease progress, and survival.
METHODS
The protocol of this study was registered in PROSPERO (registration No. CRD42019121494). We electronically searched published studies through January 2019 with the aim of finding articles that investigated the prevalence of depression among BC survivors. Web of Science, Scopus, PubMed/MEDLINE, Science Direct, and Google Scholar were searched to obtain relevant published studies. This review included 14 cross-sectional and 4 cohort studies published from 2000 to 2018. We used a random-effects model to conduct the meta-analysis and generated a summary estimate for the pooled prevalence with 95% confidence intervals (CIs). A subgroup analysis was also conducted based on the depression assessment tool used and the study design.
RESULTS
The total sample size of the studies contained 2,799 women with BC, including 1,228 women who were diagnosed with depression. The pooled prevalence of depression among Iranian women with BC was 46.83% (95% CI, 33.77 to 59.88) with significant heterogeneity (I2 =98.5%; p<0.001). The prevalence of depression ranged from 14.00% (95% CI, 4.91 to 23.09) to 95.90% (95% CI, 91.97 to 99.83). The results of the subgroup analyses suggested that the depression assessment tool, year of publication, and study design were sources of heterogeneity.
CONCLUSIONS
Our findings indicate a high prevalence of depression among BC patients, underscoring the urgent need for clinicians and health authorities to provide well-defined social and psychological supportive care programs for these patients.
Summary

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Original Articles
Life expectancy of HIV-positive patients after diagnosis in Iran from 1986 to 2016: A retrospective cohort study at national and sub-national levels
Mohammad Mirzaei, Maryam Farhadian, Jalal Poorolajal, Parvin Afasr Kazerooni, Katayoun Tayeri, Younes Mohammadi
Epidemiol Health. 2018;40:e2018053.   Published online November 7, 2018
DOI: https://doi.org/10.4178/epih.e2018053
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AbstractAbstract PDF
Abstract
OBJECTIVES
Little is known about the life expectancy of individuals with human immunodeficiency virus (HIV) in Iran. This study therefore aimed to estimate the life expectancy of HIV-positive patients in Iran.
METHODS
In this retrospective cohort study, we extracted data from the Center for Disease Control and Prevention of the Ministry of Health and Medical Education and the Death Registration System. We included patients aged 20 years and older who had a specified date of diagnosis. We estimated life expectancy and its 95% confidence intervals (CIs) using Chiang’s methodology.
RESULTS
The overall life expectancy at the national level was 23.1 years (95% CI, 22.6 to 23.5). Life expectancy was 21.6 years (95% CI, 21.1 to 22.0) for men and 32.7 years (95% CI, 31.4 to 34.0) for women. The life expectancy of patients who did or did not receive antiretroviral therapy (ART) was 37.0 years (95% CI, 36.2 to 37.8) and 15.5 years (95% CI, 15.1 to 15.9), respectively. The life expectancy of patients with or without tuberculosis (TB) was 21.6 years (95% CI, 20.4 to 22.9) and 36.5 years (95% CI, 35.7 to 37.4), respectively.
CONCLUSIONS
The life expectancy of Iranian HIV-positive patients was found to be very low. To improve their longevity, improvements in ART coverage and the control and treatment of TB are advised.
Summary

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Ambient air quality and subjective stress level using Community Health Survey data in Korea
Myung-Jae Hwang, Hae-Kwan Cheong, Jong-Hun Kim, Youn Seo Koo, Hui-Young Yun
Epidemiol Health. 2018;40:e2018028.   Published online June 28, 2018
DOI: https://doi.org/10.4178/epih.e2018028
  • 23,745 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Air pollution causes various disease in exposed populations, and can lead to premorbid health effects manifested as both physical and psychological functional impairment. The present study investigated the subjective stress level in daily life in relation to the level of air pollution.
METHODS
Data from the Community Health Survey (2013), comprising 99,162 men, and 121,273 women residing in 253 healthcare administrative districts, were combined with air pollutant concentration modelling data from the Korean Air Quality Forecasting System, and were stratified by subjective stress levels into five strata for multiple logistic regression. Levels of exposure were divided into five quintiles according to the annual concentration of nitrogen dioxide (NO2), and were analyzed using a single-pollutant model using NO2 concentration only, and a multi-pollutant model adjusted for the concentration of particulate matter <10 μm in diameter.
RESULTS
Analysis of men and women in various age groups showed the highest odds ratio (OR) for subjective stress level at the highest NO2 concentration quintile in men and women aged 30–64 years (men: 2.91; 95% confidence interval [CI], 2.12 to 4.01; women: 1.82; 95% CI, 1.32 to 2.51). As the NO2 concentration quintile increased, the OR increased. Men showed higher ORs than women in all strata.
CONCLUSIONS
In the present study, annual NO2 concentrations were found to be associated with subjective stress levels. This association was especially clear among socioeconomically active men and women aged 30-64 years.
Summary
Korean summary
2013년 지역사회건강조사를 이용하여 253개 보건행정지역단위로 Korean Air Quality Forecasting System (KAQFS) 대기물질농도 모델링자료를 결합하여 주관적 스트레스 정도에 따라 5분위로 범주화하여 다항로지스틱회귀을 하였다. 본 연구에서는 연평균 NO2농도와 주관적 스트레스 정도가 관련이 있는 것으로 나타났다. 특히, 사회 경제적 활동이 활발한30세 이상 65세 미만의 남성과 여성에서 관련성이 뚜렷하게 나타났다.

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  • High-Resolution Daily PM2.5 Exposure Concentrations in South Korea Using CMAQ Data Assimilation with Surface Measurements and MAIAC AOD (2015–2021)
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Knowledge, attitudes, and behavioural risk factors regarding zoonotic infections among bushmeat hunters and traders in Nsukka, southeast Nigeria
Kingsley Uchenna Ozioko, Chris Ikem Okoye, Rose Nduka Obiezue, Raymond Awudu Agbu
Epidemiol Health. 2018;40:e2018025.   Published online June 16, 2018
DOI: https://doi.org/10.4178/epih.e2018025
  • 31,209 View
  • 283 Download
  • 17 Web of Science
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AbstractAbstract PDF
Abstract
OBJECTIVES
In light of the dramatic spread of Ebola virus in some parts of Africa and the 2014 outbreak in Nigeria, a study was conducted to evaluate bushmeat dealers’ knowledge and attitudes about zoonotic infections and the risk of transmission to humans.
METHODS
A cross-sectional survey was conducted in a community in Nsukka, southeast Nigeria. Hunters (n=34) and bushmeat traders (n=42) were interviewed. A semi-structured questionnaire was used to generate the data. The Fisher exact test was used to evaluate the significance of differences between these groups.
RESULTS
Only 11.8% of the hunters, as compared to 35.7% of the traders, had no knowledge of possible causes of zoonotic infections (p<0.05). However, 64.7% of the hunters, compared to 38.1% of the traders, were ignorant regarding the responsibility of public health personnel and veterinarians (p<0.05), and 76.5% of the hunters compared to 42.9% of the traders were ignorant regarding the existence of zoonoses in Nigeria (p<0.05). A statistically significant difference was also found between these groups regarding the risk of contracting an infection from ectoparasites (p<0.05). The attitudes of respondents towards zoonotic diseases did not differ significantly between the groups.
CONCLUSIONS
The level of awareness about zoonotic diseases was low in this area, underscoring the need for interventions.
Summary

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  • Knowledge, Attitude, and Practices to Foodborne Zoonotic Diseases and Their Associated Factors in and Around Debre Tabor City, Northwest Ethiopia
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Determinants of health-related quality of life in Iranian adults: evidence from a cross-sectional study
Satar Rezaei, Mohammad Hajizadeh, Ali Kazemi, Masoud Khosravipour, Farid Khosravi, Shahab Rezaeian
Epidemiol Health. 2017;39:e2017038.   Published online August 15, 2017
DOI: https://doi.org/10.4178/epih.e2017038
  • 25,969 View
  • 235 Download
  • 20 Web of Science
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AbstractAbstract PDF
Abstract
OBJECTIVES
This study aimed to measure the level and determinants of health-related quality of life (HRQoL) in adults in Kermanshah, a city in the western region of Iran.
METHODS
Convenience sampling was employed to obtain a sample of 998 adults aged 18 years and older (646 males and 352 females) in the city of Kermanshah. A 2-part self-administered questionnaire was used to collect data over the period between March 1 and May 30, 2017. The first part was designed to collect information on socio-demographic characteristics, socioeconomic status, and lifestyle factors (10 items). The second part consisted of the EuroQoL 5-dimensions (EQ-5D) EuroQoL-3-level and the EuroQoL visual analog scale (EQ-VAS) questions. A multiple linear regression model was used to determine the factors associated with the EQ-5D index and EQ-VAS score among study participants.
RESULTS
The mean values for the EQ-5D index and the EQ-VAS score were 0.74 (standard deviation [SD], 0.19) and 80.9 (SD, 16.5), respectively. The highest percentage of self-reported problems (‘some’ and ‘severe’ problems) across the 5 dimensions of the EQ-5D index were associated with the dimensions of anxiety/depression (35.3%) and pain/discomfort (32.9%). The percentage of self-reported problems for the dimensions of usual activities, mobility, and self-care were 19.0, 12.8, and 8.9%, respectively. Our regression analyses indicated that there were statistically significant positive associations between being physically active, monthly household income per capita, and post-secondary education and the EQ-5D index and EQ-VAS score. In contrast, negative associations were found between older age, being married, having a chronic disease, and smoking and the EQ-5D index and EQ-VAS score. A negative association was also found between being uninsured and the EQ-5D index.
CONCLUSIONS
Our findings suggest that interventions aiming to improve physical activity, to prevent chronic diseases, and to reduce the smoking rate among adults living in the city of Kermanshah may improve their HRQoL.
Summary

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The impact of disease characteristics on multiple sclerosis patients’ quality of life
Aziz Rezapour, Abdollah Almasian Kia, Sahar Goodarzi, Mojtaba Hasoumi, Soraya Nouraei Motlagh, Sajad Vahedi
Epidemiol Health. 2017;39:e2017008.   Published online February 19, 2017
DOI: https://doi.org/10.4178/epih.e2017008
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AbstractAbstract PDF
Abstract
OBJECTIVES
The aim of this study was to assess the quality of life (QoL) of patients with multiple sclerosis (MS), and to investigate the effects of characteristics of MS such as disease course, severity, and relapses on patients’ QoL.
METHODS
This was a cross-sectional study, in which 171 patients were enrolled. Health-related QoL was assessed using the Persian version of the Multiple Sclerosis Quality of Life-54 questionnaire. To measure patients’ disability status, we used the Expanded Disability Status Scale. Other variables included in the study were disease course and relapses of the disease.
RESULTS
The average scores for patients’ physical and mental QoL were 60.9±22.3 and 59.5±21.4, respectively. In a bivariate analysis, disease course, severity of the disease, and relapses were significantly associated with the physical and mental health composite scores. In a hierarchal regression analysis, disease course, severity of the disease, and relapses were responsible for 38 and 16% of the variance in physical and mental QoL, respectively. It was also observed that relapses were a strong predictor of both physical and mental QoL.
CONCLUSIONS
Our results showed that disease characteristics significantly affected both dimensions of QoL. It is therefore suggested that health care providers should be aware of these characteristics of MS to more successfully improve MS patients’ QoL.
Summary

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Associations between a health-promoting lifestyle and quality of life among adults with beta-thalassemia major
Aghbabak Maheri, Roya Sadeghi, Davoud Shojaeizadeh, Azar Tol, Mehdi Yaseri, Mojtaba Ebrahimi
Epidemiol Health. 2016;38:e2016050.   Published online November 15, 2016
DOI: https://doi.org/10.4178/epih.e2016050
  • 28,343 View
  • 332 Download
  • 25 Web of Science
  • 22 Crossref
AbstractAbstract PDF
Abstract
OBJECTIVES
A health-promoting lifestyle (HPL) is a factor that affects the quality of life (QoL) in patients with beta-thalassemia (β-thalassemia). Due to the lack of studies of this issue, this study aimed to determine the association between HPL and QoL among adults with β-thalassemia.
METHODS
This cross-sectional (descriptive-analytic) study was conducted among 389 adult patients with β-thalassemia in Tehran, Iran. The research instrument included a questionnaire consisting of three parts: demographic items, the Short-Form Health Survey and the Health-Promoting Lifestyle Profile. The data were analyzed using SPSS version 23.0. The results were considered significant at the conventional p<0.05 level.
RESULTS
The mean age of the participants was 30.2±8.3 years. The mean score of the HPL dimensions was 127.28±21.53, and the mean score of the QoL domains was 61.44±23.38. The highest and the lowest mean scores of the HPL dimensions were found for spiritual growth (23.96±5.74) and physical activity (11.32±3.95), respectively. The QoL scores in all three domains (total, physical component summary score, and mental component summary score) were moderate. Health responsibility, physical activity, spiritual growth, and interpersonal relations were significant predictive factors of QoL in adults with β-thalassemia; these four dimensions explained 37.9% of the variance in QoL.
CONCLUSIONS
QoL and HPL were not at acceptable levels among patients with thalassemia. Therefore, educational interventions emphasizing spiritual growth, physical activity, and interpersonal relations are necessary for patients with thalassemia.
Summary

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Life and health satisfaction in the adult population of Iran
Rajabali Daroudi, Arash Rashidian, Hojjat Zeraati, Alireza Oliyaeemanesh, Ali Akbari Sari
Epidemiol Health. 2016;38:e2016047.   Published online November 3, 2016
DOI: https://doi.org/10.4178/epih.e2016047
  • 25,871 View
  • 190 Download
  • 11 Web of Science
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AbstractAbstract PDF
Abstract
OBJECTIVES
Increasing interest has emerged in the use of subjective well-being as a development indicator and for the evaluation of public policies. The aim of this study was to assess life and health satisfaction and their determinants in the adult population of Iran.
METHODS
We conducted a survey of a sample of 3,150 adults at least 18 years of age in Tehran, the capital of Iran. The subjects were selected using a stratified random sampling method, and they were interviewed face-to-face at their usual residence by trained interviewers. Life satisfaction was used as a measure of subjective well-being. We used ordinary least square regression models to assess the associations of life and health satisfaction with socio-demographic variables.
RESULTS
On a 0-10 scale, the mean (standard deviation) scores for life and health satisfaction were 6.93 (2.54) and 7.18 (1.97), respectively. The average score for life satisfaction in females was 0.52 points higher than in males. A U-shaped relationship was found between age and life satisfaction, with respondents 35 to 44 years of age having the lowest average level of life satisfaction. Satisfaction with life and health among divorced respondents was significantly lower than among never-married and married participants. The scores for life satisfaction in respondents who rated their health status as poor were 3.83 points lower than in those who rated their health status as excellent.
CONCLUSIONS
The majority of the population of Tehran was satisfied with their life and health. Self-rated health status had the greatest impact on life satisfaction.
Summary

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Self-reported health-related quality of life (HRQoL) and factors affecting HRQoL among individuals with health insurance in Iran
Ali Kazemi Karyani, Arash Rashidian, Sarar Emamgholipour Sefiddashti, Ali Akbari Sari
Epidemiol Health. 2016;38:e2016046.   Published online October 26, 2016
DOI: https://doi.org/10.4178/epih.e2016046
  • 26,119 View
  • 242 Download
  • 31 Web of Science
  • 32 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
The aim of this study was to measure the health-related quality of life (HRQoL) and to evaluate the factors affecting HRQoL in individuals with health insurance in Tehran, Iran.
METHODS
A cross-sectional analytical study was conducted using the 3-level EuroQol 5-dimensions (EQ-5D) questionnaire. In order to estimate the determinants of HRQoL, information about participants’ demographic, socioeconomic, and health status was gathered. The cluster sampling technique was used to collect data from May to June, 2016. The chi-square test and weighted least squares method were employed for data analysis. Data were analyzed using Stata version 11.0.
RESULTS
A total of 600 Iranians with insurance completed the study, of whom 327 (54.5%) were male and 273 (45.5%) were female. The mean age of the participants was 41.48 years (standard deviation [SD], 14.60 years). Meanwhile, the mean duration of education was 12.36 years (SD, 4.68 years). The mean EQ-5D score was 0.74 (SD, 0.16). The most common health problems in the participants were anxiety/depression (42.3%), followed by pain/discomfort (39.2%). Sex, age, years of schooling, income, chronic disease, and body mass index had a significant effect on HRQoL (p<0.05). Healthy insured individuals, on average, had a HRQoL score 0.119 higher than that of people with a chronic disease, all else being equal (p<0.001).
CONCLUSIONS
Among all determinants of HRQoL, chronic disease was found to be the highest priority for interventions to improve the health status of Iranians with insurance. This finding can help policymakers and health insurance organizations improve their planning to promote the HRQoL of individuals with insurance and society as a whole in Iran.
Summary
Korean summary
본 연구는 만 19세 이상의 한국 성인 동성애자와 양성애자를 대상으로 이들의 건강상태에 대한 설문조사를 시행하고, 수집한 자료를 분석하여 동성애자•양성애자의 건강불평등 실태를 파악하고자 하였다. 본 연구의 목적은 자가평가건강, 정신건강(우울, 자살생각 및 자살시도), 신체적 건강(근골격계 통증) 및 건강관련행동(흡연율, 위험음주율)을 포함하여 다양한 측면에서 한국 성인 동성애자•양성애자와 일반인구집단의 건강수준을 비교하는 것이다.

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Application of the World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF) to patients with cataract
Ali Gholami, Mahmood Tavakoli Araghi, Fatemeh Shamsabadi, Mahdiye Bayat, Fatemeh Dabirkhani, Farhad Moradpour, Kamyar Mansori, Yousef Moradi, Abdolhalim Rajabi
Epidemiol Health. 2016;38:e2016005.   Published online February 4, 2016
DOI: https://doi.org/10.4178/epih.e2016005
  • 36,661 View
  • 401 Download
  • 17 Web of Science
  • 17 Crossref
AbstractAbstract PDF
Abstract
OBJECTIVES
Cataract is a prevalent disease in the elderly, and negatively influences patients’ quality of life. This study was conducted to study the application of the World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF) to patients with cataract.
METHODS
In this cross-sectional study, 300 patients with cataract were studied in Neyshabur, Iran from July to October 2014. The Iranian version of the WHOQOL-BREF questionnaire was used to measure their quality of life. Cronbach’s alpha coefficient, Pearson’s correlation coefficient, the paired t-test, the independent t-test, and a linear regression model were used to analyze the data in SPSS version 16.0 (SPSS Inc., Chicago, IL, USA).
RESULTS
The mean age of the participants was 68.11±11.98 years, and most were female (53%). The overall observed Cronbach’s alpha coefficient for the WHOQOL-BREF was 0.889, ranging from 0.714 to 0.810 in its four domains. The total mean score of the respondents on the WHOQOL-BREF was 13.19. The highest and lowest mean scores were observed in the social relationship domain (14.11) and the physical health domain (12.29), respectively. A backward multiple linear regression model found that duration of disease and marital status were associated with total WHOQOL scores, while age, duration of disease, marital status, and income level were associated with domains one through four, respectively (p<0.05).
CONCLUSIONS
The reliability analysis conducted in this study indicated that the WHOQOL-BREF scale exhibited an acceptable degree of internal consistency in the measurement of the quality of life of patients with cataract. It was also found that the patients with cataract who were surveyed reported a relatively moderate quality of life.
Summary

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Epidemiological evaluation quality of life in patients suffering from early rheumatoid arthritis: a pragmatic, prospective, randomized, blind allocation controlled of a modular program group intervention
Hadi Yousefi, Arvind Chopra, Rez Farrokhseresht, Sanjeev Sarmukaddam, Fariba Asadi Noghabi, Nilima Bedekar, Abdolhosain Madani
Epidemiol Health. 2015;37:e2015048.   Published online November 5, 2015
DOI: https://doi.org/10.4178/epih/e2015048
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AbstractAbstract PDF
Abstract
OBJECTIVES
Epidemiology has taken on new roles in the management of health care services. In this study, we developed a non-pharmacological self-management modular program group intervention and evaluated its efficacy as an adjunct therapy in patients suffering from early rheumatoid arthritis (RA). METHODS: Patients were randomized to either participate in a non-equivalent intervention group along with the standard of care or only receive standard-of-care treatment at a community rheumatology center. The outcomes measured were a pain visual analog scale (VAS), patient general health (GH) on a VAS, and the Short Form-36 Version 2 (SF-36v2) scale measuring quality of life. These parameters were evaluated in the first week to obtain baseline values, and at 20, 32, 48, and 60 weeks to evaluate the efficacy of the intervention group. RESULTS: The patients were randomized, with 100 patients in the intervention group and 106 in the control group. The intervention and control groups were similar with regard to the percentage of women (86% vs. 89.6%), tobacco usage (25% vs. 19.8%), mean age (42.6±13.2 years vs. 46.6±10.9 years), and disease duration (15.3±6.7 months vs. 14.5±6.6 months). The mean outcomes were significantly different between the two groups, and post-hoc pairwise analysis demonstrated significant deterioration in the control group in contrast to improvement in the intervention group at the second, third, fourth, and fifth evaluations. Improvements were often seen as early as the 12-week and 24-week follow-up visits. CONCLUSIONS: Epidemiology contributes to the evaluation of how well specific therapies or other health interventions prevent or control health problems. The modular program group intervention implemented in this study appears to be a suitable and feasible method to facilitate much more comprehensive management of early RA in socioeconomically challenged communities.
Summary

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Methods
Value-based medicine: concepts and application
Jong-Myon Bae
Epidemiol Health. 2015;37:e2015014.   Published online March 4, 2015
DOI: https://doi.org/10.4178/epih/e2015014
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Global healthcare in the 21st century is characterized by evidence-based medicine (EBM), patient-centered care, and cost effectiveness. EBM involves clinical decisions being made by integrating patient preference with medical treatment evidence and physician experiences. The Center for Value-Based Medicine suggested value-based medicine (VBM) as the practice of medicine based upon the patient-perceived value conferred by an intervention. VBM starts with the best evidence-based data and converts it to patient value-based data, so that it allows clinicians to deliver higher quality patient care than EBM alone. The final goals of VBM are improving quality of healthcare and using healthcare resources efficiently. This paper introduces the concepts and application of VBM and suggests some strategies for promoting related research.
Summary
Korean summary
21세기 의학은 근거기반, 환자중심, 비용효과적인 의료를 지향하고 있다. 근거기반의학은 의사결정에 있어 최선의 의학적 근거를 기반으로 하려는 패러다임이다. 이런 근거기반의학에 더하여 환자의 가치를 치료 결정에 적극 반영하기 위하여 가치기반의학이 제기되었다. 가치기반의학은 최선의 근거에 따라 진료를 하면서도 의료자원을 효율적으로 사용하도록 만들어서, 궁극적으로 한 나라의 보건의료의 질적 향상을 도모하게 한다. 본 논문의 목적은 가치기반의학의 개념을 소개하고 관련 연구의 활성화를 위한 전략적 제언을 하는 것이다.

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Original Articles
Burden of Disease of Multiple Sclerosis in Korea
Soo-Eun Chung, Hae-Kwan Cheong, Jae-Hyun Park, Ho Jin Kim
Epidemiol Health. 2012;34:e2012008.   Published online November 30, 2012
DOI: https://doi.org/10.4178/epih/e2012008
  • 32,057 View
  • 161 Download
  • 22 Crossref
AbstractAbstract PDF
Abstract
<sec><title>OBJECTIVES</title><p>Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. There are few reports on the burden of disease of MS, worldwide. The authors aim to estimate burden of disease and estimate the epidemiologic indexes of MS in Korea using available epidemiologic data.</p></sec><sec><title>METHODS</title><p>Epidemiologic indexes were computed using DISMOD II software based on prevalence from nationwide survey, incidence estimated from extrapolation, mortality from National Statistics Office, and duration of disease from literature as input indexes. We calculated disability-adjusted life year (DALY) as a measure of premature mortality and disability, equivalent to years of healthy life lost due to a given condition.</p></sec><sec><title>RESULTS</title><p>The incidence of MS in Korea was 0.1 per 100,000, higher in female than in male. The highest incidence was estimated in the age group between 35 and 44 years in male and age group between 25 and 29 years in female. Total burden of disease of MS was 1,394 DALY, comprised of 292 (21%) years of life lost and 1,101 (79%) years lived with disability. The mean age at onset of MS was 33 years old in men and 32 years old in female. Estimated duration of disease was 35 years in men and 40 years in female. Most of the DALY of MS occurred in the adult population between 25 and 54 years of age.</p></sec><sec><title>CONCLUSION</title><p>Although MS is a rare disease in Korea, most of the DALY arises from young people, which results in a major financial burden on the patient, family, health system and society.</p></sec>
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The Burden of Premature Mortality in Hamadan Province in 2006 and 2010 Using Standard Expected Years of Potential Life Lost: A Population-based Study
Jalal Poorolajal, Nader Esmailnasab, Jamal Ahmadzadeh, Tahereh Azizi Motlagh
Epidemiol Health. 2012;34:e2012005.   Published online August 31, 2012
DOI: https://doi.org/10.4178/epih/e2012005
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AbstractAbstract PDF
Abstract
<sec><title>OBJECTIVES</title><p>Examining the premature death rate represents the first step in estimating the overall burden of disease, reflecting a full picture of how different causes affect population health and providing a way of monitoring and evaluating population health. The present study was conducted to assess the burden of premature mortality in Hamadan Province, Iran in 2006 and 2010.</p></sec><sec><title>METHODS</title><p>To calculate years of potential life lost (YPLL), the dataset was categorized into 5-year age groups based on each person's age at death. Then the age groups were subtracted from the relevant age-based life table produced by the World Health Organization in 2009. The YPLL for each individual were then added together to yield the total YPLL for all individuals in the population who died in a particular year. Finally, we calculated the YPLL for all sex-, age-, and cause-specific mortality rates and reported them as percentages.</p></sec><sec><title>RESULTS</title><p>We analyzed 18,786 deaths, 9,127 of which occurred in 2006 and 9,659 in 2010. Mortality rates were higher in men than women for all age groups both in 2006 and 2010. In addition, age-specific mortality rates in both genders for all age groups were higher in 2010 than in 2006. The percentage of YPLL from ischemic heart diseases, cerebrovascular diseases, transport accidents, and intentional self-harm were among the greatest sources of premature death.</p></sec><sec><title>CONCLUSION</title><p>The results of the present survey indicate that the eight major causes of premature death in both 2006 and 2010 were non-communicable diseases, especially ischemic heart diseases, cerebrovascular diseases, transport accidents, and intentional self-harm. Furthermore, our findings indicate a change in the role of non-communicable diseases in premature mortality in recent years.</p></sec>
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Association of Lifestyle and Hypertension in Rural Population.
Byung Mann Cho
Korean J Epidemiol. 1998;20(1):51-59.
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AbstractAbstract PDF
Abstract
To evaluate the association of individual health-related lifestyle and hypertension in rual population, data from a population sample of 633(257 men and 376 women) aged 40 years and older and residing in a rural area were analyxed cross-sectionally. The data had been collected by personal interview using structured questionnaire during August 1996. In multivariate analysis, adjusted prevalence rate ration of bypertension increased significantly with increasing amount of coffee drinkin(cups/day) in men(p=0.029) and body mass indes(kh/m2) in women(p=0.013). The level of perceiving his or her own health status was a positive correlate of hypertension in men(p=0.034) and women(p=0.107). Thus, in this population hypertension appears to be associated with coffee drinking in men, body mass index in women and the proportion of awareness of his or her own hypertension seems to be low.
Summary

Epidemiol Health : Epidemiology and Health
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