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Original Article
- Analysis of survival data in thalassemia patients in Shiraz, Iran
- Abdolreza Rajaeefard, Mahmoud Hajipour, Hamid Reza Tabatabaee, Jafar Hassanzadeh, Shahab Rezaeian, Zahra Moradi, Mehdi Sharafi, Mohsen Shafiee, Ali Semati, Sanaz Safaei, Maryam Soltani
- Epidemiol Health. 2015;37:e2015031. Published online July 7, 2015
- DOI: https://doi.org/10.4178/epih/e2015031
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- 15 Web of Science
- 9 Crossref
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Abstract
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AbstractOBJECTIVES
The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.METHODSThis retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.RESULTSOverall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.CONCLUSIONSSociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate. -
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Citations
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- Atrial Fibrillation in β-Thalassemia: Overview of Mechanism, Significance and Clinical Management
Michele Malagù, Federico Marchini, Alessio Fiorio, Paolo Sirugo, Stefano Clò, Elisa Mari, Maria Rita Gamberini, Claudio Rapezzi, Matteo Bertini
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Orphanet Journal of Rare Diseases.2021;[Epub] CrossRef - Eradication of hepatitis C virus infection in thalassemia patients in Iran using various treatment strategies
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Journal of Virus Eradication.2020; 6(3): 100006. CrossRef - Changing patterns in the epidemiology of β‐thalassemia
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European Journal of Haematology.2020; 105(6): 692. CrossRef - Molecular characterization of β-thalassemia intermedia in the West Bank, Palestine
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BMC Hematology.2019;[Epub] CrossRef - The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran
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Epidemiology and Health.2018; 40: e2018048. CrossRef - The era of comparable life expectancy between thalassaemia major and intermedia: Is it time to revisit the major‐intermedia dichotomy?
Angela Vitrano, Giuseppina Calvaruso, Eliana Lai, Grazia Colletta, Alessandra Quota, Calogera Gerardi, Luciana Concetta Rigoli, Lorella Pitrolo, Liana Cuccia, Francesco Gagliardotto, Aldo Filosa, Vincenzo Caruso, Crocetta Argento, Saveria Campisi, Michele
British Journal of Haematology.2017; 176(1): 124. CrossRef - Poor quality of life as a predictor of survival among thalassemia patients in Iran
Shahab Rezaeian
Epidemiology and Health.2017; 39: e2017013. CrossRef - Trends in 5-, 10-, 20-, and 30-Year Survival Rates of Beta-Thalassemia Patients in Southern Iran, 1995-2016: A Retrospective Cohort Study
Jafar Hassanzadeh, Alireza Mirahmadizadeh, Mehran Karimi, Yousef Veisani, Shahab Rezaeian
Journal of Public Health Research.2017; 6(3): jphr.2017.1001. CrossRef
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