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Data resource profile: the allergic disease database of the Korean National Health Insurance Service
Sunyong Yoo, Dong-Wook Kim, Young-Eun Kim, Jong Heon Park, Yeon-Yong Kim, Kyu-dong Cho, Mi-Ji Gwon, Jae-In Shin, Eun-Joo Lee
Epidemiol Health. 2021;43:e2021010.   Published online January 21, 2021
DOI: https://doi.org/10.4178/epih.e2021010
  • 15,130 View
  • 433 Download
  • 3 Web of Science
  • 3 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
Researchers have been interested in probing how the environmental factors associated with allergic diseases affect the use of medical services. Considering this demand, we have constructed a database, named the Allergic Disease Database, based on the National Health Insurance Database (NHID). The NHID contains information on demographic and medical service utilization for approximately 99% of the Korean population. This study targeted 3 major allergic diseases, including allergic rhinitis, atopic dermatitis, and asthma. For the target diseases, our database provides daily medical service information, including the number of daily visits from 2013 and 2017, categorized by patients’ characteristics such as address, sex, age, and duration of residence. We provide additional information, including yearly population, a number of patients, and averaged geocoding coordinates by <i>eup, myeon</i>, and <i>dong</i> district code (the smallest-scale administrative units in Korea). This information enables researchers to analyze how daily changes in the environmental factors of allergic diseases (e.g., particulate matter, sulfur dioxide, and ozone) in certain regions would influence patients’ behavioral patterns of medical service utilization. Moreover, researchers can analyze long-term trends in allergic diseases and the health effects caused by environmental factors such as daily climate and pollution data. The advantages of this database are easy access to data, additional levels of geographic detail, time-efficient data-refining and processing, and a de-identification process that minimizes the exposure of identifiable personal information. All datasets included in the Allergic Disease Database can be downloaded by accessing the National Health Insurance Service data sharing webpage (https://nhiss.nhis.or.kr).
Summary
Korean summary
알레르기질환DB는 환경적 변화와 의료이용 연관성 연구를 지원하기 위해 만들어진 누구나 다운로드 가능한 공개용DB이다. 알레르기질환DB는 한국 전국민의 사회인구학적 특성 및 의료이용 정보가 구축되어 있는 국민건강보험공단의 국민건강정보DB를 활용하여 구축되었다. 알레르기질환DB는 2013년~2017년 알레르기성 비염, 아토피, 천식 상병코드로 청구된 의료이용 정보를 제공하고 있으며, 이를 활용하여 특정 지역에 다양한 환경적 변화와 의료이용과의 연관성 연구 등에 활발히 활용될 것으로 기대된다.
Key Message
The Allergic Disease Database based on the National Health Insurance Data is constructed for analyzing how environmental factors affect the use of medical services. The database provides most Korean medical service information of allergic diseases, such as allergic rhinitis, atopic dermatitis, and asthma from 2013 and 2017. This information enables researchers to study how daily changes of environmental factors in certain regions would influence patients’ behavioral patterns of medical service utilization. Moreover, researchers can analyze the long-term trend of allergic diseases, and health effects caused by environmental factors such as daily climate and pollution data.

Citations

Citations to this article as recorded by  
  • Evaluation of the Regulatory Required Post-Authorization Safety Study for Propacetamol: Nested Case-Control and Case-Time-Control Studies
    Sungho Bea, Dongwon Yoon, Han Eol Jeong, Juhong Jung, Seung-Mok Park, Juhee Jeon, Young-Min Ye, Jae-Hyun Lee, Ju-Young Shin
    Yonsei Medical Journal.2024; 65(2): 120.     CrossRef
  • The relationship between exposure to environmental noise and risk of atopic dermatitis, asthma, and allergic rhinitis
    Yongho Lee, Seunghyun Lee, Seula Park, Seong-Kyu Kang, June-Hee Lee, Dong-Wook Lee, Won-Jun Choi, Wanhyung Lee
    Ecotoxicology and Environmental Safety.2023; 268: 115677.     CrossRef
  • Increased risk of cataract surgery in patients with allergic disease: a population based cohort study
    Ji-Sun Paik, Kyungdo Han, Gahee Nam, Sun-Kyoung Park, Ho Sik Hwang, Yoon Hong Chun, Kyung-Sun Na
    Scientific Reports.2022;[Epub]     CrossRef
Original Article
Estimating causal associations of atopic dermatitis with depression using the propensity score method: an analysis of Korea Community Health Survey data, 2010-2013
Hayon Michelle Choi, Dahye Kim, Whanhee Lee, Ho Kim
Epidemiol Health. 2018;40:e2018059.   Published online November 29, 2018
DOI: https://doi.org/10.4178/epih.e2018059
  • 14,583 View
  • 193 Download
  • 9 Web of Science
  • 7 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Numerous studies have reported associations between atopic dermatitis (AD) and depression, but the causal relationship between the 2 diseases has not been established. Therefore, this study used the propensity score method to investigate whether there was a positive causal effect of AD on depression in 16 regions (cities and provinces) in Korea.
METHODS
The study analyzed 16 regions (cities and provinces) in Korea, using data obtained from the Korea Community Health Survey for the years 2010-2013. Propensity score matching was used to estimate the causal influence of AD on depression in Korea.
RESULTS
After propensity score matching, the standardized difference for each covariate among the 16 regions (cities and provinces) was less than 1, indicating a balance between the case and control groups. At the national level, those diagnosed with AD had a 2.31 times higher risk for being diagnosed with depression than those who had not been diagnosed with AD. In particular, the risk was highest in North Jeolla Province (odds ratio [OR], 4.87; 95% confidence interval [CI], 2.28 to 10.43) and lowest in Gwangju (OR, 1.82; 95% CI, 0.87 to 3.79), and the OR for Seoul was 2.23 (95% CI, 1.66 to 2.99).
CONCLUSIONS
This study provides insights into how causal inferences can be derived from observational studies, through an analysis of Korea Community Health Survey data. Furthermore, the study results have implications for region-specific guidelines for preventive health policies targeting depression.
Summary
Korean summary
성향 점수 매칭을 이용하여 전국 및 16개 시/도 별 아토피 피부염과 우울증 사이의 인과성을 추정한 결과, 전국에서 아토피 피부염을 진단 받은 사람이 진단 받지 않은 사람들에 비해 우울증 위험도가 2.38배 높았다(CI: 1.29-4.38).

Citations

Citations to this article as recorded by  
  • Epidemiology of mental health comorbidity in patients with atopic dermatitis: An analysis of global trends from 1998 to 2022
    Xiao‐ce Cai, Si‐han Wang, Chun‐xiao Wang, Liu Liu, Jiao Wang, Yu‐hong Shen, Xin Li
    Journal of the European Academy of Dermatology and Venereology.2024; 38(3): 496.     CrossRef
  • Risk of depression in patients with atopic dermatitis: An updated systematic review and meta‐analysis of children, adolescent and adult groups
    Lihua Cao, Jiangwei Su, Fang Tian, Yang Zhou, Songchun Liu, Fanglu Lou
    Journal of Paediatrics and Child Health.2024; 60(11): 640.     CrossRef
  • Analysis of Quality of Life and Mental Health in Patients With Atopic Dermatitis, Asthma and Allergic Rhinitis Using a Nation-wide Database, KNHANES VII
    Gyu Na Lee, Ha Yeh Rin Koo, Kyungdo Han, Young Bok Lee
    Allergy, Asthma & Immunology Research.2022; 14(2): 273.     CrossRef
  • Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review
    Qing Long, Hongxia Jin, Xu You, Yilin Liu, Zhaowei Teng, Yatang Chen, Yun Zhu, Yong Zeng, Dong Keon Yon
    PLOS ONE.2022; 17(2): e0263334.     CrossRef
  • Impairment of Quality of Life and Mental Health Status in Adult-Onset Atopic Dermatitis
    Juhwan Yoo, Ha Yeh Rin Koo, Kyungdo Han, Young Bok Lee
    Annals of Dermatology.2022; 34(4): 278.     CrossRef
  • Combined Oral and Topical Application of Pumpkin (Cucurbita pepo L.) Alleviates Contact Dermatitis Associated With Depression Through Downregulation Pro-Inflammatory Cytokines
    Maha Jameal Balgoon, Maryam H. Al-Zahrani, Soad Al Jaouni, Nasra Ayuob
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Association of atopic dermatitis with suicide risk among 788,411 adolescents
    Yechan Kyung, Min Hwan Choi, Yoo Jung Jeon, Ju Suk Lee, Jun Hwa Lee, Seon Hui Jo, Sung Hoon Kim
    Annals of Allergy, Asthma & Immunology.2020; 125(1): 55.     CrossRef

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