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Pau-Chung Chen 1 Article
Data resource profile: the National Health Insurance Research Database (NHIRD)
Liang-yu Lin, Charlotte Warren-Gash, Liam Smeeth, Pau-Chung Chen
Epidemiol Health. 2018;40:e2018062.   Published online December 27, 2018
DOI: https://doi.org/10.4178/epih.e2018062
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AbstractAbstract PDFSupplementary Material
Abstract
Electronic health records (EHRs) can provide researchers with extraordinary opportunities for population-based research. The National Health Insurance system of Taiwan was established in 1995 and covers more than 99.6% of the Taiwanese population; this system’s claims data are released as the National Health Insurance Research Database (NHIRD). All data from primary outpatient departments and inpatient hospital care settings after 2000 are included in this database. After a change and update in 2016, the NHIRD is maintained and regulated by the Data Science Centre of the Ministry of Health and Welfare of Taiwan. Datasets for approved research are released in three forms: sampling datasets comprising 2 million subjects, disease-specific databases, and full population datasets. These datasets are de-identified and contain basic demographic information, disease diagnoses, prescriptions, operations, and investigations. Data can be linked to government surveys or other research datasets. While only a small number of validation studies with small sample sizes have been undertaken, they have generally reported positive predictive values of over 70% for various diagnoses. Currently, patients cannot opt out of inclusion in the database, although this requirement is under review. In conclusion, the NHIRD is a large, powerful data source for biomedical research.
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    Clinical Epidemiology.2020; Volume 12: 185.     CrossRef
  • Preadmission Antihypertensive Drug Use and Sepsis Outcome: Impact of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin Receptor Blockers (ARBs)
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    International Journal of Environmental Research and Public Health.2020; 17(8): 2913.     CrossRef
  • Effect of early eradication therapy on systemic lupus erythematosus risk in patients with Helicobacter pylori infection: a nationwide population-based cohort study
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    Neuropsychiatric Disease and Treatment.2020; Volume 16: 1249.     CrossRef
  • Risk of ankylosing spondylitis following human papillomavirus infection: A nationwide, population-based, cohort study
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  • Creating the BELgian COngenital heart disease database combining administrative and clinical data (BELCODAC): Rationale, design and methodology
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