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Maryam Soltani 1 Article
Analysis of survival data in thalassemia patients in Shiraz, Iran
Abdolreza Rajaeefard, Mahmoud Hajipour, Hamid Reza Tabatabaee, Jafar Hassanzadeh, Shahab Rezaeian, Zahra Moradi, Mehdi Sharafi, Mohsen Shafiee, Ali Semati, Sanaz Safaei, Maryam Soltani
Epidemiol Health. 2015;37:e2015031.   Published online July 7, 2015
DOI: https://doi.org/10.4178/epih/e2015031
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Abstract
OBJECTIVES
The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.
METHODS
This retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.
RESULTS
Overall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.
CONCLUSIONS
Sociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate.
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  • Trends in 5-, 10-, 20-, and 30-Year Survival Rates of Beta-Thalassemia Patients in Southern Iran, 1995-2016: A Retrospective Cohort Study
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