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Investigating SARS-CoV-2 infection and the health and psychosocial impact of the COVID-19 pandemic in the Canadian CHILD Cohort
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Rilwan Azeez, Larisa Lotoski, Aimée Dubeau, Natalie Rodriguez, Myrtha E. Reyna, Tyler Freitas, Stephanie Goguen, Maria Medeleanu, Geoffrey L. Winsor, Fiona S.L. Brinkman, Emily E. Cameron, Leslie Roos, Elinor Simons, Theo J. Moraes, Piush J. Mandhane, Stuart E. Turvey, Shelly Bolotin, Kim Wright, Deborah McNeil, David M. Patrick
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Epidemiol Health. 2023;e2023091. Published online October 13, 2023
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DOI: https://doi.org/10.4178/epih.e2023091
[Accepted]
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 Abstract
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Abstract
The COVID-19 pandemic has affected all Canadian families, with some impacted differently than others. Our study aims to: (1) determine the prevalence and transmission of SARS-CoV-2 infection among Canadian families, (2) identify predictors of infection susceptibility and (3) identify health and psychosocial impacts of the COVID-19 pandemic.
This study builds upon the CHILD Cohort Study, an ongoing multi-ethnic general population prospective cohort consisting of 3454 Canadian families with children born in Vancouver, Edmonton, Manitoba, and Toronto between 2009-12. During the pandemic, CHILD households were invited to participate in the CHILD COVID-19 Add-on Study involving: (1) brief biweekly surveys about COVID-19 symptoms and testing; (2) quarterly questionnaires assessing COVID-19 exposure and testing, vaccination status, physical and mental health, and pandemic-driven life changes; (3) in-home biological sampling kits to collect blood and stool.
1462 households (5378 participants) consented to the CHILD COVID-19 Add on study: 2803 children (mean age 9years; SD 2.7, range 0-17) and 2576 adults (mean age 43years; SD 6.5, range 18-85).
We will leverage pre-pandemic CHILD data to identify risk and resilience factors for susceptibility and severity to the direct and indirect pandemic effects. Our short-term findings will inform key stakeholders and knowledge users to shape current and future pandemic responses.
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Summary
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